Department of Pediatrics
USF Health · College of Medicine

Recent Lab Research News and Publication

Grants

National Institutes of Health (R01; Linask, Subcontract).
Title:Investigating Early Embryonic Murine Heart using Optical Coherence Tomography.
Collaboration with Dr. Andrew Rollins, Case Western Reserve Universty

Suncoast Cardiovascular Research and Education Foundation
Title:Validation of Folate Responsive Genes in Cardiac Development.
Funding was provided by the Suncoast Cardiovascular Research and Education Foundation, founded by Helen Harper Brown.

News

The Linask Lab presented a poster at the recent Weinstein 2011 meeting in Cincinnati. The authors and titles:

  • Lifeng Zhang, Mingda Han, and Kersti K. Linask. Modulation of Wnt/β-Catenin and Phosphatidylinositol Signaling by Lithium and Epigenetic-Related Effects.

  • Dr. Kersti K. Linask will present a talk at the upcoming 2011 Research Society on Alcoholism meeting in Atlanta, GA, June 25-29. She is part of the NIAAA sponsored symposium on "Gene-nutrient interactions in disease development in alcoholics: Folates and retinoids" to be held on Sunday, June 26th between 10:00 AM-12:00 Noon. Talk is entitled: Folate Protection Of Fetal Alcohol Syndrome Associated Cardiac Defects By Modulation Of Wnt/Β-Catenin Signaling.

    • Recent Publications

    Serrano, M., Brinez, P., Han, M., Lastra-Vicente, R., and K.K. Linask. 2010. Fetal Alcohol Syndrome: Cardiac birth defects and prevention with folate. Amer. J. Obst. Gyn. 203(1):75.e7-75.e15.
    The above article was reported in Science Daily.

    Linask, K.L. and Linask, K.K. 2010. Calcium channel blockade in embryonic cardiac progenitor cells disrupts normal cardiac cell differentiation. Stem Cells and Development. (doi:10.1089/scd.2010.0192)

    Linask, K.K. and J.C. Huhta. 2010. Folate protection of congenital heart defects associated with canonical Wnt signaling and epigenetic. Curr. Opin. in Pediatrics. 22:561-566.

    Garita, B. M.W. Jenkins, M. Han, C. Zhou, M. VanAuker, A. M. Rollins, M. Watanabe, J.G. Fujimoto, and K. K. Linask. 2011. Blood Flow Dynamics of One Cardiac Cycle and Relationship to Mechanotransduction and Trabeculation during Heart Looping. Am. J P. Heart Circulatory Physiol. 300(3):H879-891.
    This article was a featured article in the month of April on the online Oct News.

    Patent Pending

    An international Patent Application was filed by USF on March 5, 2010 in relation to Dr. Linask's folate research.