Department of Pediatrics
USF Health · College of Medicine

Hye-Seung Lee, PhD, MS

Dr. Lee is a native of Seoul, South Korea, where she earned her BS and MS degrees.  At Korea University she was a researcher on projects involving statistical methods for identification using DNA, including paternity testing and criminal identification.  She was awarded a biostatistics fellowship at Columbia University in NY, where she earned her PhD degree.  At Columbia University, she worked at the Neurological Institute as a statistician on the Northern Manhattan Stroke Study and at the Sergievsky Center where she was an analyst for a project investigating gene identification in Alzheimer disease and memory decline.  She also completed a certificate program in Advanced Gene Mapping and Linkage at Rockefeller University in 2004. 

Dr. Lee joined the USF faculty in 2006 as an Assistant Professor at the Pediatrics Epidemiology Center.  Her research interest is the development of statistical methods for gene mapping of complex diseases.  She is an author on nearly 30 publications and frequently speaks at national and international research conferences. Dr. Lee is currently an investigator for the Rare Disease Clinical Research Network and the Environmental Determinants of Diabetes in the Young. 

Education & Training

 

BS Ewha Womans University, Seoul, South Korea; Statistics, 1995
MS Korea University, Seoul, South Korea; Statistics, 1998
PhD Columbia University, NY, NY; Biostatistics, 2006

 

Scholarly Interests

  • Linkage analyses for quantitative traits
  • Regression modeling for correlations
  • Longitudinal data analysis
  • Family studies

Selected Publications

  • Lee H-S and Lee JW. Statistical methods in criminal inference using DNA fingerprints. Computational Statistics and Data Anal 1999; 32: 47-67.

  • Lee H-S Lee JW, Han GR and Hwang JJ. Motherless case in paternity testing. Forensic Sci Int 2000; 114: 57-65.

  • Sacco RL, Anand K, Lee H-S, B-A B, Stabler SP, Allen RH and Paik MC. Homocysteine and the risk of ischemic stroke in a tri-ethnic cohort: The Northern Manhattan Study. Stroke 2004; 35: 2263-2269.

  • Shibata N, Kawarai T, Lee JH, Lee H-S, Shibata E, Sato C, Liang Y, Duara R, Mayeux RP, St George-Hyslop PH and Rogaeva E. Association studies of cholesterol metabolism genes (CH25H, ABCA1 and CH24H) in Alzheimer’s disease. Neurosci Lett 2006; 391(3): 142-146.

  • Lee, H-S. Canonical correlation analysis using small number of samples. Communications in Statistics: Simulation and Computation 2007; 36(5): 973-985.

  • Lee H-S, Paik MC and Lee JH. Genotype adjusted familial correlation analysis using three generalized estimating equations. Stat Med 2008; 27(26), 5471-5483.

  • Lee H-S, Paik MC and Lee JH. Estimating a multivariate familial correlation using Joint models for canonical correlations: Application to memory score analysis from familial Hispanic Alzheimer's disease study. Biometrics 2009; 65; 463-469.