John P. Cannon, PhD
Dr. Cannon is originally from St. Petersburg, Florida. He obtained his PhD in 1997 from Baylor College of Medicine, studying the development of hematopoietic cells in the mouse embryo. In 2000, he joined Dr. Gary Litman’s laboratory at the University of South Florida Department of Pediatrics as a Postdoctoral Fellow and since 2005 has been a Research Assistant Professor.
Dr. Cannon’s major research interests are focused on the function of various families of immunoglobulin superfamily receptors in innate immune recognition and the regulation of the early immune response.
Education & Training
| B.S. | University of Miami, Florida, 1990 |
| Ph.D | Baylor College of Medicine, Houston, Texas, 1997 |
Scholarly Activity
Current funding
- All Children’s Hospital Foundation Institutional Research Grant, CD300 function in innate immune surveillance and response, 9/08-8/11
Rsearch focus
- Comparative studies of orthologs of mammalian immune receptors in alternative vertebrate systems
- The role of CD300 and TREM/TLT molecules in establishment and regulation of the innate immune response
- Interplay of innate and adaptive immune responses during the emergence of nascent malignancies
Selected Publications
Cannon JP, Haire RN, Litman GW. Identification of diversified genes that contain immunoglobulin-like variable regions in a protochordate. Nature Immunology, 2002, 3, 1200-1207.
Cannon JP, Haire RN, Schnitker N, Mueller MG, Litman GW. Individual protochordates possess unique immune-type receptor repertoires. Current Biology, 2004, 14, R465-466.
Litman GW, Cannon JP, Dishaw LJ. Reconstructing immune phylogeny: new perspectives. Nature Reviews Immunology, 2005, 5, 866-879.
Hernández Prada JA, Haire RN, Allaire M, Jakoncic J, Stojanoff V, Cannon JP, Litman GW, Ostrov DA. Ancient evolutionary origin of diversified variable regions revealed by crystal structures of an amphioxus VCBP. Nature Immunology, 2006, 7, 875-882.
Cannon JP, Haire RN, Magis AT, Eason DD, Winfrey KN, Hernandez Prada JA, Bailey KM, Jakoncic J, Litman GW, Ostrov DA. A bony fish immunological receptor of the NITR multigene family mediates allogeneic recognition. Immunity, 2008, 29, 228-237.
