ArdeshirHakam

Ardeshir Hakam, MD MBA

Professor, College Of Medicine Pathology & Cell Biology

Professor, Department Of Oncologic Sciences

Department Of Oncologic Sciences

Director of Oncologic Surgical Pathology Fellowship Program, Pathology, University of South Florida

Director of Surgical Pathology, Anatomic Pathology, Moffitt Cancer Center

Contact Info 12902 Magnolia Drive
MCC 2071 J
Tampa, FL 33612

Academic Email: ahakam@health.usf.edu

Education

  • Fellowship, Genitourinary and Gastrointestinal Pathology, University of Pittsburgh Medical Center, 2011
  • Fellowship, Cytopathology, University of South Florida, 1999
  • Fellowship, Oncologic Surgical Pathology, Universith of South Florida, 1998
  • Pathology Residency, Pathology, University of Hawaii, 1992
  • Internship, Pathology, Vaasa Central Hospital, 1986
  • MD, Medicine, Universidad Eugenio Maria De Hostos*, 1985
  • MBA, Management & International Business, Xavier University, 1981

Interdisciplinary and Emerging Signature Programs

  • Women & Children's Health

Research Interests

  • Gynecological and Urological neoplasms.
  • Cytopathology

Recent Publications

  • Nasir, A.Boulware, D.Kaiser, HE.Lancaster, JM.Coppola, D.Smith, PV.Hakam, A.Siegel, SE.Bodey, B. Cyclooxygenase-2 (COX-2) expression in human endometrial carcinoma and precursor lesions and its possible use in cancer chemoprevention and therapy. In vivo (Athens, Greece). 21(1) : 35-43http://www.ncbi.nlm.nih.gov/pubmed/17354612
  • Hakam, A.Nasir, A.Raghuwanshi, R.Smith, PV.Crawley, S.Kaiser, HE.Grendys, E.Fiorica, JF. Value of multilevel sectioning for improved detection of micrometastases in sentinel lymph nodes in invasive squamous cell carcinoma of the vulva. Anticancer research. 24(2C) : 1281-6http://www.ncbi.nlm.nih.gov/pubmed/15154661
  • Nasir, A.Helm, J.Turner, L.Chen, DT.Strosberg, J.Hafez, N.Henderson-Jackson, EB.Hodul, P.Bui, MM.Nasir, NA.Hakam, A.Malafa, MP.Yeatman, TJ.Coppola, D.Kvols, LK. RUNX1T1: a novel predictor of liver metastasis in primary pancreatic endocrine neoplasms. Pancreas. 40(4) : 627-33, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21499216
  • Morgan, RJ.Alvarez, RD.Armstrong, DK.Boston, B.Burger, RA.Chen, LM.Copeland, L.Crispens, MA.Gershenson, D.Gray, HJ.Grigsby, PW.Hakam, A.Havrilesky, LJ.Johnston, C.Lele, S.Matulonis, UA.O'Malley, DM.Penson, RT.Remmenga, SW.Sabbatini, P.Schilder, RJ.Schink, JC.Teng, N.Werner, TL. Epithelial ovarian cancer. Journal of the National Comprehensive Cancer Network : JNCCN. 9(1) : 82-113, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21233246
  • Henderson-Jackson, EB.Helm, J.Ghayouri, M.Hakam, A.Nasir, A.Leon, M.Bui, M.Yeatman, T.Coppola, D. Correlation between Mcl-1 and pAKT protein expression in colorectal cancer. International journal of clinical and experimental pathology. 3(8) : 768-74, 2010. http://www.ncbi.nlm.nih.gov/pubmed/21151390
  • Riddle, ND.Gorden, L.Rojiani, MV.Hakam, A.Rojiani, AM. CD44 and p53 immunoexpression patterns in NF1 neoplasms - indicators of malignancy and infiltration. International journal of clinical and experimental pathology. 3(5) : 515-21, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20606732
  • Indermaur, MD.Xiong, Y.Kamath, SG.Boren, T.Hakam, A.Wenham, RM.Apte, SM.Lancaster, JM. Genomic-directed targeted therapy increases endometrial cancer cell sensitivity to doxorubicin. American journal of obstetrics and gynecology. 203(2) : 158.e1-40, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20444440
  • Allam-Nandyala, P.Bui, MM.Caracciolo, JT.Hakam, A. Squamous cell carcinoma and osteosarcoma arising from a dermoid cyst--a case report and review of literature. International journal of clinical and experimental pathology. 3(3) : 313-8, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20224730
  • Henderson-Jackson, E.Nasir, NA.Hakam, A.Nasir, A.Coppola, D. Primary mixed lymphoepithelioma-like carcinoma and intra-hepatic cholangiocarcinoma: a case report and review of literature. International journal of clinical and experimental pathology. 3(7) : 736-41, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20830246
  • Shackelford, RE.Bui, MM.Coppola, D.Hakam, A. Over-expression of nicotinamide phosphoribosyltransferase in ovarian cancers. International journal of clinical and experimental pathology. 3(5) : 522-7, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20606733
  • Bui, MM.Purohit, CN.Hakam, A. Fine needle aspiration biopsy of an osteoclast-rich undifferentiated urothelial carcinoma: A cytology case report and review of the literature. CytoJournal. 7: 18, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20976205
  • Boren, T.Xiong, Y.Hakam, A.Wenham, R.Apte, S.Chan, G.Kamath, SG.Chen, DT.Dressman, H.Lancaster, JM. MicroRNAs and their target messenger RNAs associated with ovarian cancer response to chemotherapy. Gynecologic oncology. 113(2) : 249-55, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19237188
  • Hoffman, MS.Williams, V.Salihu, HM.Gunasekaran, S.Sayer, RA.Hakam, A.Roberts, WS. The vascular portion of the cardinal ligament: surgical significance during radical hysterectomy for cervical cancer. American journal of obstetrics and gynecology. 199(2) : 191.e1-7; discussion 191.e7, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18554569
  • Boren, T.Xiong, Y.Hakam, A.Wenham, R.Apte, S.Wei, Z.Kamath, S.Chen, DT.Dressman, H.Lancaster, JM. MicroRNAs and their target messenger RNAs associated with endometrial carcinogenesis. Gynecologic oncology. 110(2) : 206-15, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18499237
  • Cox, C.Centeno, B.Dickson, D.Clark, J.Nicosia, S.Dupont, E.Greenberg, H.Stowell, N.White, L.Patel, J.Furman, B.Cantor, A.Hakam, A.Ahmad, N.Diaz, N.King, J. Accuracy of intraoperative imprint cytology for sentinel lymph node evaluation in the treatment of breast carcinoma. Cancer. 105(1) : 13-20, 2005. http://www.ncbi.nlm.nih.gov/pubmed/15605359
  • Hakam, A.Khin, NN. Intraoperative imprint cytology in assessment of sentinel lymph nodes and lumpectomy surgical margins. Clinics in laboratory medicine. 25(4) : 795-807, viii, 2005. http://www.ncbi.nlm.nih.gov/pubmed/16308093
  • Reed, J.Hakam, A.Nicosia, SV.Coppola, D. Significance of Fas receptor protein expression in epithelial ovarian cancer. Human pathology. 36(9) : 971-6, 2005. http://www.ncbi.nlm.nih.gov/pubmed/16153459
  • Nasir, A.Kaiser, HE.Boulware, D.Hakam, A.Zhao, H.Yeatman, T.Barthel, J.Coppola, D. Cyclooxygenase-2 expression in right- and left-sided colon cancer: a rationale for optimization of cyclooxygenase-2 inhibitor therapy. Clinical colorectal cancer. 3(4) : 243-7, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15025797
  • Weinberg, ES.Dickson, D.White, L.Ahmad, N.Patel, J.Hakam, A.Nicosia, S.Dupont, E.Furman, B.Centeno, B.Cox, C. Cytokeratin staining for intraoperative evaluation of sentinel lymph nodes in patients with invasive lobular carcinoma. American journal of surgery. 188(4) : 419-22, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15474439
  • Hakam, A.Fang, Q.Karl, R.Coppola, D. Coexpression of IGF-1R and c-Src proteins in human pancreatic ductal adenocarcinoma. Digestive diseases and sciences. 48(10) : 1972-8, 2003. http://www.ncbi.nlm.nih.gov/pubmed/14627343
  • Cardosi, RJ.Speights, A.Fiorica, JV.Grendys, EC.Hakam, A.Hoffman, MS. Bartholin's gland carcinoma: a 15-year experience. Gynecologic oncology. 82(2) : 247-51, 2001. http://www.ncbi.nlm.nih.gov/pubmed/11531274
  • Diaz, JI.Mora, LB.Hakam, A. The Mainz Classification of Renal Cell Tumors. Cancer control : journal of the Moffitt Cancer Center. 6(6) : 571-579, 1999. http://www.ncbi.nlm.nih.gov/pubmed/10756388
  • Hakam, A.Yeatman, TJ.Lu, L.Mora, L.Marcet, G.Nicosia, SV.Karl, RC.Coppola, D. Expression of insulin-like growth factor-1 receptor in human colorectal cancer. Human pathology. 30(10) : 1128-33, 1999. http://www.ncbi.nlm.nih.gov/pubmed/10534157
  • Getzenberg, RH.Konety, BR.Oeler, TA.Quigley, MM.Hakam, A.Becich, MJ.Bahnson, RR. Bladder cancer-associated nuclear matrix proteins. Cancer research. 56(7) : 1690-4, 1996. http://www.ncbi.nlm.nih.gov/pubmed/8603421

Awards/Honors

  • Teacher of the Year (USF Pathology Residents - 2010)
  • Teacher of the year (USF Pathology Residents - 2000)