Cesario Borlongan, MA, PHD




Contact Info MDC 78
12901 Bruce B Downs Blvd
Tampa, FL 33612

Academic Email: cborlong@health.usf.edu

Academic Phone: (813) 974-3988

View My C.V.


  • PHD, Psychology, Keio University, 1994

Interdisciplinary and Emerging Signature Programs

  • Allergy, Immunology & Infectious Disease
  • Biomedical Engineering & Nanomedicine
  • Cancer Biology
  • Cardiovascular
  • Cardiovascular Sciences
  • Cellular and Molecular Biology
  • Metabolic Regulation and Disorders
  • Neurodegenerative Disease
  • Neuroscience
  • Oxygen Toxicity
  • Women & Children's Health

Research Interests

  • CESAR V. BORLONGAN, Ph.D. is a world leader in stem cell therapy for stroke. His translational bench to clinic research has led to 5 FDA-approved clinical trials of cell transplantation, including the world’s first cell therapy in stroke patients. He served as an NIH Staff Fellow for 5 years, joined the academe in 2002, becoming a Professor in the Department of Neurology at the Medical College of Georgia, with continuous multiple federal funding from VA, DoD, and NIH. He is an author of more than 310 peer-reviewed publications, lead editor of 2 books, and serves as editor of many scientific journals, including Stem Cells, Stroke, JCBFM, PLoS One, and Brain Research. He is a regular study section member of NIH, VA, DOD,and AHA, chairs the State of Maryland Stem Cell Research Funds. He is an AAAS Fellow, serves as President of the American Society for Neural Therapy and Repair, and the International Placenta Stem Cell Society. He was featured in The Lancet Neurology “Lifeline” of 2008.

Recent Publications

  • Acosta SA, Tajiri N, Hoover J, Kaneko Y, Borlongan CV. Intravenous Bone Marrow Stem Cell Grafts Preferentially Migrate to Spleen and Abrogate Chronic Inflammation in Stroke. Stroke; a journal of cerebral circulation. 46(9) : 2616-27, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26219646
  • Kaneko Y, Sullivan R, Dailey T, Vale FL, Tajiri N, Borlongan CV. Kainic acid-induced golgi complex fragmentation/dispersal shifts the proteolysis of reelin in primary rat neuronal cells: an in vitro model of early stage epilepsy Molecular Neurobiology. : In press, 2015. http://www.ncbi.nlm.nih.gov/pubmed/23077646
  • dela Peña IC, Yoo A, Tajiri N, Acosta SA, Ji X, Kaneko Y, Borlongan CV. Granulocyte colony-stimulating factor attenuates delayed tPA-induced hemorrhagic transformation in ischemic stroke rats by enhancing angiogenesis and vasculogenesis. Journal of Cerebral Blood Flow & Metabolism. 35(2) : 338-46, 2015. http://www.ncbi.nlm.nih.gov/pubmed/22734824
  • Acosta SA, Tajiri N, de la Pena I, Bastawrous M, Sanberg PR, Kaneko Y, Borlongan CV. Alpha-synuclein as a pathological link between chronic traumatic brain injury and Parkinson's disease. Journal of cellular physiology. 230(5) : 1024-32, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25251017
  • Diamandis T, Borlongan CV. One, two, three steps toward cell therapy for stroke. Stroke; a journal of cerebral circulation. 46(2) : 588-91, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25503552
  • Poulos SG, Richie WD, Bailey RK, Lee A, Dela Peña I, Sanberg PR, Borlongan CV. The potential of neural stem cell transplantation for the treatment of fetal alcohol spectrum disorder. Progress in neuro-psychopharmacology & biological psychiatry. 54: 149-56, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24943998
  • Kaneko Y, Shojo H, Burns J, Staples M, Tajiri N, Borlongan CV. DJ-1 ameliorates ischemic cell death in vitro possibly via mitochondrial pathway. Neurobiology of disease. 62: 56-61, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24060818
  • Acosta SA, Tajiri N, Shinozuka K, Ishikawa H, Sanberg PR, Sanchez-Ramos J, Song S, Kaneko Y, Borlongan CV. Combination therapy of human umbilical cord blood cells and granulocyte colony stimulating factor reduces histopathological and motor impairments in an experimental model of chronic traumatic brain injury. PloS one. 9(3) : e90953, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24621603
  • Tajiri N, Kaneko Y, Shinozuka K, Ishikawa H, Yankee E, McGrogan M, Case C, Borlongan CV. Stem cell recruitment of newly formed host cells via a successful seduction? Filling the gap between neurogenic niche and injured brain site. PloS one. 8(9) : e74857, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24023965
  • Tajiri N, Kellogg SL, Shimizu T, Arendash GW, Borlongan CV. Traumatic brain injury precipitates cognitive impairment and extracellular Aβ aggregation in Alzheimer's disease transgenic mice. PloS one. 8(11) : e78851, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24223856
  • Ishikawa H, Tajiri N, Shinozuka K, Vasconcellos J, Kaneko Y, Lee HJ, Mimura O, Dezawa M, Kim SU, Borlongan CV. Vasculogenesis in experimental stroke after human cerebral endothelial cell transplantation. Stroke; a journal of cerebral circulation. 44(12) : 3473-81, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24130140
  • Ishikawa H, Tajiri N, Vasconcellos J, Kaneko Y, Mimura O, Dezawa M, Borlongan CV. Ischemic stroke brain sends indirect cell death signals to the heart. Stroke; a journal of cerebral circulation. 44(11) : 3175-82, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24008571
  • Acosta SA, Tajiri N, Shinozuka K, Ishikawa H, Grimmig B, Diamond DM, Diamond D, Sanberg PR, Bickford PC, Kaneko Y, Borlongan CV. Long-term upregulation of inflammation and suppression of cell proliferation in the brain of adult rats exposed to traumatic brain injury using the controlled cortical impact model. PloS one. 8(1) : e53376, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23301065
  • Borlongan CV, Glover LE, Tajiri N, Kaneko Y, Freeman TB. The great migration of bone marrow-derived stem cells toward the ischemic brain: therapeutic implications for stroke and other neurological disorders. Progress in neurobiology. 95(2) : 213-28, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21903148
  • Borlongan CV. Bone marrow stem cell mobilization in stroke: a 'bonehead' may be good after all! Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 25(11) : 1674-86, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21727900