Carmelina Gemma, Ph.D.
Department of Neurosurgery and Brain Repair MDC 78University of South Florida College of Medicine
12901 Bruce B. Downs Blvd
Tampa, FL 33612
Neuroinflammation and Neurodegenerative Diseases
|Research Description||My laboratory is geared towards unraveling the potential of hippocampus as a therapeutic target site for stimulating endogenous neurogenesis in aging and age-related disorders, such as Parkinson's disease. To this end, I am interested in demonstrating the key role of hippocampal neurogenesis in regenerative medicine following stem cell therapy, anti-inflammatory drugs, and other cell-based treatments (i.e., nutrition and herbal medicine) in relevant animal models.|
|Recent Publications||Bachstetter AD, Morganti JM, Jernberg J, Schlunk A, Mitchell SH, Brewster KW, Hudson CE, Cole MJ, Harrison JK, Bickford PC, Gemma C. Fractalkine and CX(3)CR1 regulate hippocampal neurogenesis in adult and aged rats. Neurobiol Aging. 2009 Dec 15.
Park DH, Eve DJ, Sanberg PR, Musso Iii J, Bachstetter AD, Wolfson A, Schlunk A, Baradez MO, Sinden JD, Bickford PC, Gemma C. Increased neuronal proliferation in the dentate gyrus of aged rats following neural stem cell implantation. Stem Cells Dev. 2009 Jul 1
Bachstetter AD, Pabon MM, Cole MJ, Hudson CE, Sanberg PR, Willing AE, Bickford PC, Gemma C. Peripheral injection of human umbilical cord blood stimulates neurogenesis in the aged rat brain. BMC Neurosci. 2008 Feb 14;9:22.