Image of Pythagoras Brain

Courtesy of Zenografia, Inc

To Participate: interested participants please contact Kelly Elliott at the HDSA Center of Excellence (813) 974-6022

ENROLL-HD: A Prospective Registry Study in a Global HD Cohort

  • Purpose of the study is to build a database of information about people affected with HD
  • The registry will include a repository of biological samples that will allow researchers and clinicians to better understand the progression of the disease.
  • Each patient's individual data will be de-identified so that all private health information will be secure.

2CARE: Coenzyme CoQ10 in Huntington's Disease

  • Purpose is to assess the effect of high doses of CoQ10 on slowing the worsening of HD symptoms.
  • Assess safety and acceptability of CoQ10 in long term use.
  • Individuals diagnosed with early to moderate HD
  • Randomly assigned CoQ10 or placebo
  • 5 year study
  • Active, call regarding enrollment

CREST-E: Creatine Safety, Tolerability & Efficacy in Huntington's Disease

  • Purpose is to assess whether high doses of creatine can slow down the worsening of HD symptoms that occur over time.
  • Assess creatine's safety in long-term use and look at how it affects the body and brain.
  • Individuals diagnosed with early to moderate HD
  • Randomly assigned creatine or placebo
  • 3 year study
  • Active, call regarding enrollment

Clinical Trials: 

2 CARE “Enrollment Closed” 
OMS824-HDT-002 (Omeros) - Contact center for enrollment criteria