Faculty

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Clifton Gooch, MD

Chair, College Of Medicine Neurology

Professor and Chairman, Neurology, College of Medicine, USF

Director, USF Neuroscience Collaborative, Neurology, College of Medic, University of South

Contact Info 12901 Bruce B. Downs Blvd MDC 55
Tampa, FL 33612

Academic Email: cgooch@health.usf.edu

Academic Phone: (813) 974-3541

View My C.V.

Education

  • MD, Medicine, Baylor College Of Medicine, 1988
  • MD, Medicine, Baylor College of Medicine, 1988
  • BA, British Literature, Transylvania University, 1984

Interdisciplinary and Emerging Signature Programs

  • Neurodegenerative Disease
  • Neuroscience

Research Interests

  • Neuromuscular Disease: Clinical and Translational Research in Neuromuscular, Neurodegenerative and Neuroimmunological Disease, Human and Animal Electrophysiology, studies of motor axon and motor unit function.
  • Specific Areas: Neuropathy, Motor Neuron Diseases and ALS, Nerve Injury and Entrapment, Neuromuscular Junction Disorders, Primary Muscle Disease, Neuroimmunological Disorders

Memberships

  • American Neurologic Association (Chair, Public Committee, 2013 - Present)
  • American Association of Neuromuscular & Electrodiagnostic Medicine (Chair, Awards Committee, 2013 - Present)
  • United Council of Neurological Subspecialties (UCNS) (Accreditation Council Member (Delegate from the American Neurological Assn.), 2012 - Present)
  • American Neurologic Association (Strategic Planning Task Force, 2012 - Present)
  • American Association of Medical Colleges (Council of Academic Societies (Delegate from the AANEM), 2011 - Present)
  • American Academy of Neurology (AAN) (Course Chair, Annual Meeting (Neuromuscular Therapeutics), 2011 - Present)
  • American Academy of Neurology (AAN) (Fellow Member, 2008 - Present)
  • American Academy of Neurology (AAN) (Course Faculty, Annual Meeting (Advanced EMG Skills), 2007 - Present)
  • American Neurologic Association (Fellow Member (Induction by Invitation), 2004 - Present)
  • American Academy of Neurology (AAN) (Member, Neuromuscular Section and Clinical Neurophysiology Section, 2001 - Present)
  • American Board of Electrodiagnostic Medicine (Fellow, 1996 - Present)
  • American Association of Neuromuscular & Electrodiagnostic Medicine (Fellow Member, 1996 - Present)
  • Association of University Professors of Neurology (Department Chair Member, 2008 - 2013)
  • American Association of Neuromuscular & Electrodiagnostic Medicine (Chair, Motor Unit Number Estimation PIRP, 2004 - 2013)
  • American Board of Electrodiagnostic Medicine (Oral Board Examiner, 2009 - 2009)
  • American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) (Board of Directors, 2006 - 2009)
  • American Academy of Neurology (AAN) (Active Member, 1995 - 2008)
  • American Academy of Neurology (AAN) (Abstract Reviewer, Annual Meeting (Neuropathy), 2007 - 2007)
  • American Academy of Neurology (AAN) (Co-Chair, Scientific Platform Session (Advanced EMG Skills), 2007 - 2007)
  • American Academy of Immunotherapy (President, 2004 - 2006)
  • American Association of Neuromuscular & Electrodiagnostic Medicine (Chair, Marketing and Public Relations Committee, 2002 - 2006)
  • American Academy of Immunotherapy (Executive Board Member, 2003 - 2004)
  • American Association of Neuromuscular & Electrodiagnostic Medicine (Chair, National Training Program Committee, 1999 - 2002)
  • American Association of Neuromuscular & Electrodiagnostic Medicine (Chair, Single Fiber EMG Special Interest Group, 1999 - 2002)
  • Texas Neurological Society (Vice President, 1998 - 1999)
  • American Association of Neuromuscular & Electrodiagnostic Medicine (Chair, Motor Unit Physiology Special Interest Group, 1996 - 1999)

Recent Publications

  • Freeman, MJ.Rose, DZ.Myers, MA.Gooch, CL.Bozeman, AC.Burgin, WS. Ischemic stroke after use of the synthetic marijuana "spice". Neurology. 81(24) : 2090-3, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24212384
  • Kaufmann, P.McDermott, MP.Darras, BT.Finkel, RS.Sproule, DM.Kang, PB.Oskoui, M.Constantinescu, A.Gooch, CL.Foley, AR.Yang, ML.Tawil, R.Chung, WK.Martens, WB.Montes, J.Battista, V.O'Hagen, J.Dunaway, S.Flickinger, J.Quigley, J.Riley, S.Glanzman, AM.Benton, M.Ryan, PA.Punyanitya, M.Montgomery, MJ.Marra, J.Koo, B.De Vivo, DC. Prospective cohort study of spinal muscular atrophy types 2 and 3. Neurology. 79(18) : 1889-97, 2012. http://www.ncbi.nlm.nih.gov/pubmed/23077013
  • Gooch, CL.Doherty, TJ. The equations of life and death: tales told by motor unit number estimation. Neurology. 77(3) : 208-9, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21676912
  • Gooch, CL.Amato, AA. Are anti-ganglioside antibodies of clinical value in multifocal motor neuropathy? Neurology. 75(22) : 1950-1, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20962289
  • Ropper, AH.Gorson, KC.Gooch, CL.Weinberg, DH.Pieczek, A.Ware, JH.Kershen, J.Rogers, A.Simovic, D.Schratzberger, P.Kirchmair, R.Losordo, D. Vascular endothelial growth factor gene transfer for diabetic polyneuropathy: a randomized, double-blinded trial. Annals of neurology. 65(4) : 386-93, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19399887
  • Gooch, CL.Pullman, SL.Shungu, DC.Ulu─č, AM.Chane, S.Gordon, PH.Tang, MX.Mao, X.Rowland, LP.Mitsumoto, H. Motor unit number estimation (MUNE) in diseases of the motor neuron: utility and comparative analysis in a multimodal biomarker study. Supplements to Clinical neurophysiology. 60: 153-62, 2009. http://www.ncbi.nlm.nih.gov/pubmed/20715377
  • Zesiewicz, TA.Sullivan, KL.Gooch, CL.Lynch, DR. Subjective improvement in proprioception in 2 patients with atypical Friedreich ataxia treated with varenicline (Chantix). Journal of clinical neuromuscular disease. 10(4) : 191-3, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19494730
  • Zesiewicz, TA.Sullivan, KL.Gooch, CL. Red flags to spot the parkinsonian variant of multiple system atrophy. Nature clinical practice. Neurology. 4(11) : 596-7, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18695708
  • Gooch, C.Shy, M. Hereditary motor neuropathy and heat shock proteins: a shocking transformation. Neurology. 71(21) : 1656-7, 2008. http://www.ncbi.nlm.nih.gov/pubmed/19015482
  • Mitsumoto, H.Ulug, AM.Pullman, SL.Gooch, CL.Chan, S.Tang, MX.Mao, X.Hays, AP.Floyd, AG.Battista, V.Montes, J.Hayes, S.Dashnaw, S.Kaufmann, P.Gordon, PH.Hirsch, J.Levin, B.Rowland, LP.Shungu, DC. Quantitative objective markers for upper and lower motor neuron dysfunction in ALS. Neurology. 68(17) : 1402-10, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17452585
  • Gooch, CL.Weimer, LH. The electrodiagnosis of neuropathy: basic principles and common pitfalls. Neurologic clinics. 25(1) : 1-28, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17324718
  • Kaufmann, P.Pascual, JM.Anziska, Y.Gooch, CL.Engelstad, K.Jhung, S.DiMauro, S.De Vivo, DC. Nerve conduction abnormalities in patients with MELAS and the A3243G mutation. Archives of neurology. 63(5) : 746-8, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16682545
  • Lange, DJ.Weimer, LH.Trojaborg, W.Lovelace, RE.Gooch, CL.Rowland, LP. Multifocal motor neuropathy with conduction block: slow but not benign. Archives of neurology. 63(12) : 1778-81, 2006. http://www.ncbi.nlm.nih.gov/pubmed/17172619
  • Kaufmann, P.Engelstad, K.Wei, Y.Jhung, S.Sano, MC.Shungu, DC.Millar, WS.Hong, X.Gooch, CL.Mao, X.Pascual, JM.Hirano, M.Stacpoole, PW.DiMauro, S.De Vivo, DC. Dichloroacetate causes toxic neuropathy in MELAS: a randomized, controlled clinical trial. Neurology. 66(3) : 324-30, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16476929
  • Stubblefield, MD.Vahdat, LT.Balmaceda, CM.Troxel, AB.Hesdorffer, CS.Gooch, CL. Glutamine as a neuroprotective agent in high-dose paclitaxel-induced peripheral neuropathy: a clinical and electrophysiologic study. Clinical oncology (Royal College of Radiologists (Great Britain)). 17(4) : 271-6, 2005. http://www.ncbi.nlm.nih.gov/pubmed/15997923
  • Gooch, CL.Mitten, DJ. Treatment of carpal tunnel syndrome: is there a role for local corticosteroid injection? Neurology. 64(12) : 2006-7, 2005. http://www.ncbi.nlm.nih.gov/pubmed/15985566
  • Rong, LL.Gooch, C.Szabolcs, M.Herold, KC.Lalla, E.Hays, AP.Yan, SF.Yan, SS.Schmidt, AM. RAGE: a journey from the complications of diabetes to disorders of the nervous system - striking a fine balance between injury and repair. Restorative neurology and neuroscience. 23(5-6) : 355-65, 2005. http://www.ncbi.nlm.nih.gov/pubmed/16477098
  • Gooch, C.Podwall, D. The diabetic neuropathies. The neurologist. 10(6) : 311-22, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15518597
  • Rong, LL.Trojaborg, W.Qu, W.Kostov, K.Yan, SD.Gooch, C.Szabolcs, M.Hays, AP.Schmidt, AM. Antagonism of RAGE suppresses peripheral nerve regeneration. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 18(15) : 1812-7, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15576484
  • Rong, LL.Yan, SF.Wendt, T.Hans, D.Pachydaki, S.Bucciarelli, LG.Adebayo, A.Qu, W.Lu, Y.Kostov, K.Lalla, E.Yan, SD.Gooch, C.Szabolcs, M.Trojaborg, W.Hays, AP.Schmidt, AM. RAGE modulates peripheral nerve regeneration via recruitment of both inflammatory and axonal outgrowth pathways. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 18(15) : 1818-25, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15576485
  • Gooch, CL.Shefner, JM. ALS surrogate markers. MUNE. Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases. 5 Suppl 1: 104-7, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15512887
  • Podwall, D.Gooch, C. Diabetic neuropathy: clinical features, etiology, and therapy. Current neurology and neuroscience reports. 4(1) : 55-61, 2004. http://www.ncbi.nlm.nih.gov/pubmed/14683630
  • Alexianu, ME.Gooch, CL. Advances in neuromuscular disease 2003: the year in review. Journal of clinical neuromuscular disease. 5(4) : 169-75, 2004. http://www.ncbi.nlm.nih.gov/pubmed/19078738
  • Mitsumoto, H.Gordon, P.Kaufmann, P.Gooch, CL.Przedborski, S.Rowland, LP. Randomized control trials in ALS: lessons learned. Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases. 5 Suppl 1: 8-13, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15512861
  • Filosto, M.Mancuso, M.Nishigaki, Y.Pancrudo, J.Harati, Y.Gooch, C.Mankodi, A.Bayne, L.Bonilla, E.Shanske, S.Hirano, M.DiMauro, S. Clinical and genetic heterogeneity in progressive external ophthalmoplegia due to mutations in polymerase gamma. Archives of neurology. 60(9) : 1279-84, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12975295
  • Shefner, JM.Gooch, CL. Motor unit number estimation. Physical medicine and rehabilitation clinics of North America. 14(2) : 243-60, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12795515
  • Azrieli, Y.Weimer, L.Lovelace, R.Gooch, C. The utility of segmental nerve conduction studies in ulnar mononeuropathy at the elbow. Muscle & nerve. 27(1) : 46-50, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12508294
  • Trojaborg, W.Kaufmann, P.Gooch, CL. Motor Unit Estimate Number in the Anterior Tibial Muscle: Normative Data versus Findings in Critically Ill Patients in Intensive Care Units. Journal of clinical neuromuscular disease. 3(4) : 139-42, 2002. http://www.ncbi.nlm.nih.gov/pubmed/19078670
  • Shefner, JM.Gooch, CL. Motor unit number estimation in neurologic disease. Advances in neurology. 88: 33-52, 2002. http://www.ncbi.nlm.nih.gov/pubmed/11908235
  • Sacconi, S.Salviati, L.Gooch, C.Bonilla, E.Shanske, S.DiMauro, S. Complex neurologic syndrome associated with the G1606A mutation of mitochondrial DNA. Archives of neurology. 59(6) : 1013-5, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12056939
  • Weimer, LH.Yin, J.Lovelace, RE.Gooch, CL. Serial studies of carpal tunnel syndrome during and after pregnancy. Muscle & nerve. 25(6) : 914-7, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12115984
  • Gooch, CL. Motor unit number estimation: pro. Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases. 3 Suppl 1: S93-4, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12396821
  • Gordon, PH.Gooch, CL.Greene, PE. Extensor digitorum brevis test and resistance to botulinum toxin type A. Muscle & nerve. 26(6) : 828-31, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12451609
  • Gooch, CL.Mosier, DR. Stimulated single fiber electromyography in the mouse: techniques and normative data. Muscle & nerve. 24(7) : 941-5, 2001. http://www.ncbi.nlm.nih.gov/pubmed/11410922
  • Harati, Y.Gooch, C.Swenson, M.Edelman, SV.Greene, D.Raskin, P.Donofrio, P.Cornblath, D.Olson, WH.Kamin, M. Maintenance of the long-term effectiveness of tramadol in treatment of the pain of diabetic neuropathy. Journal of diabetes and its complications. 14(2) : 65-70, 2000. http://www.ncbi.nlm.nih.gov/pubmed/10959067
  • Gooch, CL.Harati, Y. Motor unit number estimation, ALS and clinical trials. Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases. 1(2) : 71-82, 2000. http://www.ncbi.nlm.nih.gov/pubmed/11467053
  • Nagamitsu, S.Matsuura, T.Khajavi, M.Armstrong, R.Gooch, C.Harati, Y.Ashizawa, T. A "dystrophic" variant of autosomal recessive myotonia congenita caused by novel mutations in the CLCN1 gene. Neurology. 55(11) : 1697-703, 2000. http://www.ncbi.nlm.nih.gov/pubmed/11113225
  • Daube, JR.Gooch, C.Shefner, J.Olney, R.Felice, K.Bromberg, M. Motor unit number estimation (MUNE) with nerve conduction studies. Supplements to Clinical neurophysiology. 53: 112-5, 2000. http://www.ncbi.nlm.nih.gov/pubmed/12740984
  • Gooch, CL. Repetitive axonal stimulation of the same single motor unit: a longitudinal tracking study. Muscle & nerve. 21(11) : 1537-9, 1998. http://www.ncbi.nlm.nih.gov/pubmed/9771682
  • Harati, Y.Gooch, C.Swenson, M.Edelman, S.Greene, D.Raskin, P.Donofrio, P.Cornblath, D.Sachdeo, R.Siu, CO.Kamin, M. Double-blind randomized trial of tramadol for the treatment of the pain of diabetic neuropathy. Neurology. 50(6) : 1842-6, 1998. http://www.ncbi.nlm.nih.gov/pubmed/9633738
  • Gooch, CL.Harati, Y. Longitudinal tracking of the same single motor unit in amyotrophic lateral sclerosis. Muscle & nerve. 20(4) : 511-3, 1997. http://www.ncbi.nlm.nih.gov/pubmed/9121513
  • Shaibani, A.Gooch, C.Harati, Y. Moving toes and myoclonus associated with hereditary neuropathy with liability to pressure palsy (HNPP). Muscle & nerve. 20(7) : 881-3, 1997. http://www.ncbi.nlm.nih.gov/pubmed/9179161

Positions Held

  • Chief Medical Officer (USF Byrd Alzheimer's Institute (Interim), University of South Florida 2008 - 2009)
  • Director, Neuromuscular Physiology Laboratory (Neurology, Columbia University 1999 - 2008)
  • Director, Columbia Neuropathy Research Center (Neurology, Columbia University 2005 - 2008)
  • Professor (Neurology, Columbia University 2006 - 2008)
  • Associate Professor (Neurology, Columbia University 1999 - 2004)
  • Assistant Professor (Neurology, Baylor College of Medicine 1993 - 1999)
  • Fellow (Neuromuscular Medicine, Duke University 1992 - 1993)
  • Resident (Neurology, Baylor College of Medicine 1988 - 1992)

Awards/Honors

  • Top Doctor 2013 (U.S. News and World Report and Castle Connolly - 2013)
  • Top Doctor 2012 (U.S. News and World Report and Castle Connolly - 2012)
  • Stanley H. Appel Distinguished Lecturer, 2009 (The Methodist Neurological Institute - 2009)
  • National Institute of Health (NIH)-National Institute on Aging (NIA) ASTRA Pearls Lecture (NIH and Johns Hopkins - 2004)
  • Distinguished Achievement Award (Transylvania University - 2001)
  • Outstanding Faculty Leadership Award (Baylor College of Medicine, Dept. of Neurology - 1999)
  • Outstanding Faculty Leadership Award (Baylor College of Medicine Neurology - 1999)