Kersti Linask

Kersti Linask, PHD

Division Chief, College of Medicine Pediatrics

Professor, College of Medicine Molecular Medicine

Contact Info 140-7th Ave South
Children's Research Institute 2007
St. Petersburg FL 33701

Academic Email: klinask@health.usf.edu

View My C.V.

Education

  • PHD, University of Pennsylvania, 1986
  • MA, Developmental Biology, UCLA, 1968

Interdisciplinary and Emerging Signature Programs

  • Cardiovascular
  • Cardiovascular Sciences
  • Cellular and Molecular Biology
  • Environmental & Global Health
  • Women & Children's Health

Research Interests

  • My research interests focus on cellular and molecular mechanisms underlying early cardiac cell specification, differentiation, and heart organogenesis. Specifically, we target the cardiac precursor cell population. Currently, we are analyzing effects of alcohol inducing Fetal Alcohol Syndrome, of lithium and homocysteine, and the mechanism by which folate and with even greater efficacy, folate/myo-inositol combination prevents cardiac birth defects induced by these environmental factors. These studies have been extended into aspects of wound healing.

Recent Publications

  • Linask KK. The heart-placenta axis in the first month of pregnancy: induction and prevention of cardiovascular birth defects. Journal of pregnancy. 2013: 320413, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23691322
  • Garita B, Jenkins MW, Han M, Zhou C, Vanauker M, Rollins AM, Watanabe M, Fujimoto JG, Linask KK. Blood flow dynamics of one cardiac cycle and relationship to mechanotransduction and trabeculation during heart looping. American journal of physiology. Heart and circulatory physiology. 300(3) : H879-91, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21239637
  • Linask KK, Vanauker M. A role for the cytoskeleton in heart looping. TheScientificWorldJournal. 7: 280-98, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17334619
  • Manisastry SM, Han M, Linask KK. Early temporal-specific responses and differential sensitivity to lithium and Wnt-3A exposure during heart development. Developmental dynamics : an official publication of the American Association of Anatomists. 235(8) : 2160-74, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16804895
  • Linask KK, Manisastry S, Han M. Cross talk between cell-cell and cell-matrix adhesion signaling pathways during heart organogenesis: implications for cardiac birth defects. Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 11(3) : 200-8, 2005. http://www.ncbi.nlm.nih.gov/pubmed/16060972
  • Linask KK, Han M, Cai DH, Brauer PR, Maisastry SM. Cardiac morphogenesis: matrix metalloproteinase coordination of cellular mechanisms underlying heart tube formation and directionality of looping. Developmental dynamics : an official publication of the American Association of Anatomists. 233(3) : 739-53, 2005. http://www.ncbi.nlm.nih.gov/pubmed/15844197