BurtAnderson

Burt Anderson, Ph.D.

Professor, College Of Medicine Molecular Medicine

College Of Medicine Molecular Medicine

Professor, Molecular Medicine, USF

Contact Info 12901 Bruce B. Downs Blvd
MDC7
Tampa, FL 33612

Academic Email: banderso@health.usf.edu

Academic Phone: (813) 974-2608

View My C.V.

Education

  • PHD, Molecular Genetics, Georgia State University, 1988

Interdisciplinary and Emerging Signature Programs

  • Allergy, Immunology & Infectious Disease

Research Interests

  • The primary focus of our laboratory is how facultative intracellular bacteria control expression of genes required for virulence. We currently study how Bartonella henselae regulates expression of genes required to mediate the unique vascular proliferation that is observed in patients infected with this bacterium. In addition, we are studying gene regulatory circuits required for virulence in Francisella tularensis.

Memberships

  • Florida Center of Excellence Center for Biomolecular Identification and Targeted Therapeutics (Member, 2007 - Present)
  • SIPAIID (Member and Journal Club Coordinator, 2005 - Present)
  • H. Lee Moffitt Cancer Center and Research Institute (Member, 1997 - Present)
  • American Society for Microbiology (Member, 1986 - Present)
  • American Society of Rickettsiology (President, 2001 - 2003)

Recent Publications

  • Minnick, MF.Anderson, BE.Lima, A.Battisti, JM.Lawyer, PG.Birtles, RJ. Oroya fever and verruga peruana: bartonelloses unique to South America. PLoS neglected tropical diseases. 8(7) : e2919, 2014. http://www.ncbi.nlm.nih.gov/pubmed/25032975
  • Lima, A.Cha, BJ.Amin, J.Smith, LK.Anderson, B. Zebrafish Embryo Model of Bartonella henselae Infection. Zebrafish. 11(5) : 434-46, 2014. http://www.ncbi.nlm.nih.gov/pubmed/25026365
  • Cormier, R.Burda, WN.Harrington, L.Edlinger, J.Kodigepalli, KM.Thomas, J.Kapolka, R.Roma, G.Anderson, BE.Turos, E.Shaw, LN. Studies on the antimicrobial properties of N-acylated ciprofloxacins. Bioorganic & medicinal chemistry letters. 22(20) : 6513-20, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22995622
  • Ramaraju, P.Gergeres, D.Turos, E.Dickey, S.Lim, DV.Thomas, J.Anderson, B. Synthesis and antimicrobial activities of structurally novel S,S'-bis(heterosubstituted) disulfides. Bioorganic & medicinal chemistry letters. 22(11) : 3623-31, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22560472
  • Gillaspie, D.Perkins, I.Larsen, K.McCord, A.Pangonis, S.Sweger, D.Seleem, MN.Sriranganathan, N.Anderson, BE. Plasmid-based system for high-level gene expression and antisense gene knockdown in Bartonella henselae. Applied and environmental microbiology. 75(16) : 5434-6, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19542333
  • Sammons-Jackson, WL.McClelland, K.Manch-Citron, JN.Metzger, DW.Bakshi, CS.Garcia, E.Rasley, A.Anderson, BE. Generation and characterization of an attenuated mutant in a response regulator gene of Francisella tularensis live vaccine strain (LVS). DNA and cell biology. 27(7) : 387-403, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18613792
  • McCord, AM.Cuevas, J.Anderson, BE. Bartonella-induced endothelial cell proliferation is mediated by release of calcium from intracellular stores. DNA and cell biology. 26(9) : 657-63, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17678436
  • Dabo, SM.Confer, AW.Saliki, JT.Anderson, BE. Binding of Bartonella henselae to extracellular molecules: identification of potential adhesins. Microbial pathogenesis. 41(1) : 10-20, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16725305
  • Dabo, SM.Confer, AW.Anderson, BE.Gupta, S. Bartonella henselae Pap31, an extracellular matrix adhesin, binds the fibronectin repeat III13 module. Infection and immunity. 74(5) : 2513-21, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16622186
  • McCord, AM.Resto-Ruiz, SI.Anderson, BE. Autocrine role for interleukin-8 in Bartonella henselae-induced angiogenesis. Infection and immunity. 74(9) : 5185-5190, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16926411
  • McCord, AM.Burgess, AW.Whaley, MJ.Anderson, BE. Interaction of Bartonella henselae with endothelial cells promotes monocyte/macrophage chemoattractant protein 1 gene expression and protein production and triggers monocyte migration. Infection and immunity. 73(9) : 5735-5742, 2005. http://www.ncbi.nlm.nih.gov/pubmed/16113290
  • Riess, T.Anderson, B.Fackelmayer, A.Autenrieth, IB.Kempf, VA. Rapid and efficient transposon mutagenesis of Bartonella henselae by transposome technology. Gene. 313: 103-109, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12957381
  • Resto-Ruiz, S.Burgess, A.Anderson, BE. The role of the host immune response in pathogenesis of Bartonella henselae. DNA and cell biology. 22(6) : 431-440, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12906736
  • Ayoub, EM.McBride, J.Schmiederer, M.Anderson, B. Role of Bartonella henselae in the etiology of Henoch-Schönlein purpura. The Pediatric infectious disease journal. 21(1) : 28-31, 2002. http://www.ncbi.nlm.nih.gov/pubmed/11791094
  • Resto-Ruiz, SI.Schmiederer, M.Sweger, D.Newton, C.Klein, TW.Friedman, H.Anderson, BE. Induction of a potential paracrine angiogenic loop between human THP-1 macrophages and human microvascular endothelial cells during Bartonella henselae infection. Infection and immunity. 70(8) : 4564-4570, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12117969
  • Minnick, MF.Anderson, BE. Bartonella interactions with host cells. Sub-cellular biochemistry. 33: 97-123, 2000. http://www.ncbi.nlm.nih.gov/pubmed/10804853
  • Burgess, AW.Paquet, JY.Letesson, JJ.Anderson, BE. Isolation, sequencing and expression of Bartonella henselae omp43 and predicted membrane topology of the deduced protein. Microbial pathogenesis. 29(2) : 73-80, 2000. http://www.ncbi.nlm.nih.gov/pubmed/10906262
  • Wang, Q.Vasey, FB.Mahfood, JP.Valeriano, J.Kanik, KS.Anderson, BE.Bridgeford, PH. V2 regions of 16S ribosomal RNA used as a molecular marker for the species identification of streptococci in peripheral blood and synovial fluid from patients with psoriatic arthritis. Arthritis and rheumatism. 42(10) : 2055-9, 1999. http://www.ncbi.nlm.nih.gov/pubmed/10524676
  • Burgess, AW.Anderson, BE. Outer membrane proteins of Bartonella henselae and their interaction with human endothelial cells. Microbial pathogenesis. 25(3) : 157-64, 1998. http://www.ncbi.nlm.nih.gov/pubmed/9790875
  • Anderson, BE.Neuman, MA. Bartonella spp. as emerging human pathogens. Clinical microbiology reviews. 10(2) : 203-19, 1997. http://www.ncbi.nlm.nih.gov/pubmed/9105751
  • Arraga-Alvarado, C.Montero-Ojeda, M.Bernardoni, A.Anderson, BE.Parra, O. [Human ehrlichiosis: report of the 1st case in Venezuela] Investigación clínica. 37(1) : 35-49, 1996. http://www.ncbi.nlm.nih.gov/pubmed/8920030
  • McDade, JE.Anderson, BE. Molecular epidemiology: applications of nucleic acid amplification and sequence analysis. Epidemiologic reviews. 18(1) : 90-7, 1996. http://www.ncbi.nlm.nih.gov/pubmed/8877333
  • Holmes, AH.Greenough, TC.Balady, GJ.Regnery, RL.Anderson, BE.O'Keane, JC.Fonger, JD.McCrone, EL. Bartonella henselae endocarditis in an immunocompetent adult. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 21(4) : 1004-7, 1995. http://www.ncbi.nlm.nih.gov/pubmed/8645787
  • Demers, DM.Bass, JW.Vincent, JM.Person, DA.Noyes, DK.Staege, CM.Samlaska, CP.Lockwood, NH.Regnery, RL.Anderson, BE. Cat-scratch disease in Hawaii: etiology and seroepidemiology. The Journal of pediatrics. 127(1) : 23-6, 1995. http://www.ncbi.nlm.nih.gov/pubmed/7608806
  • Sumner, JW.Sims, KG.Jones, DC.Anderson, BE. Protection of guinea-pigs from experimental Rocky Mountain spotted fever by immunization with baculovirus-expressed Rickettsia rickettsii rOmpA protein. Vaccine. 13(1) : 29-35, 1995. http://www.ncbi.nlm.nih.gov/pubmed/7762273
  • Waldvogel, K.Regnery, RL.Anderson, BE.Caduff, R.Caduff, J.Nadal, D. Disseminated cat-scratch disease: detection of Rochalimaea henselae in affected tissue. European journal of pediatrics. 153(1) : 23-7, 1994. http://www.ncbi.nlm.nih.gov/pubmed/8313920
  • Kakoma, I.Hansen, RD.Anderson, BE.Hanley, TA.Sims, KG.Liu, L.Bellamy, C.Long, MT.Baek, BK. Cultural, molecular, and immunological characterization of the etiologic agent for atypical canine ehrlichiosis. Journal of clinical microbiology. 32(1) : 170-5, 1994. http://www.ncbi.nlm.nih.gov/pubmed/8126175
  • Sumner, JW.Sims, KG.Jones, DC.Anderson, BE. Ehrlichia chaffeensis expresses an immunoreactive protein homologous to the Escherichia coli GroEL protein. Infection and immunity. 61(8) : 3536-9, 1993. http://www.ncbi.nlm.nih.gov/pubmed/8101510
  • Anderson, BE.Sims, KG.Olson, JG.Childs, JE.Piesman, JF.Happ, CM.Maupin, GO.Johnson, BJ. Amblyomma americanum: a potential vector of human ehrlichiosis. The American journal of tropical medicine and hygiene. 49(2) : 239-44, 1993. http://www.ncbi.nlm.nih.gov/pubmed/8357086
  • Anderson, BE.Sumner, JW.Dawson, JE.Tzianabos, T.Greene, CR.Olson, JG.Fishbein, DB.Olsen-Rasmussen, M.Holloway, BP.George, EH. Detection of the etiologic agent of human ehrlichiosis by polymerase chain reaction. Journal of clinical microbiology. 30(4) : 775-80, 1992. http://www.ncbi.nlm.nih.gov/pubmed/1374076
  • Regnery, RL.Anderson, BE.Clarridge, JE.Rodriguez-Barradas, MC.Jones, DC.Carr, JH. Characterization of a novel Rochalimaea species, R. henselae sp. nov., isolated from blood of a febrile, human immunodeficiency virus-positive patient. Journal of clinical microbiology. 30(2) : 265-74, 1992. http://www.ncbi.nlm.nih.gov/pubmed/1371515
  • Anderson, BE.Greene, CE.Jones, DC.Dawson, JE. Ehrlichia ewingii sp. nov., the etiologic agent of canine granulocytic ehrlichiosis. International journal of systematic bacteriology. 42(2) : 299-302, 1992. http://www.ncbi.nlm.nih.gov/pubmed/1581189
  • Anderson, BE.Dawson, JE.Jones, DC.Wilson, KH. Ehrlichia chaffeensis, a new species associated with human ehrlichiosis. Journal of clinical microbiology. 29(12) : 2838-42, 1991. http://www.ncbi.nlm.nih.gov/pubmed/1757557
  • Dawson, JE.Anderson, BE.Fishbein, DB.Sanchez, JL.Goldsmith, CS.Wilson, KH.Duntley, CW. Isolation and characterization of an Ehrlichia sp. from a patient diagnosed with human ehrlichiosis. Journal of clinical microbiology. 29(12) : 2741-5, 1991. http://www.ncbi.nlm.nih.gov/pubmed/1757543
  • Anderson, BE.McDonald, GA.Jones, DC.Regnery, RL. A protective protein antigen of Rickettsia rickettsii has tandemly repeated, near-identical sequences. Infection and immunity. 58(9) : 2760-9, 1990. http://www.ncbi.nlm.nih.gov/pubmed/2117568

Positions Held

  • Infectious Disease Researcher VA Medical Center 1994 - 2008)
  • Associate Professor (Department of Medical Microbiology and Immunology, College of Medicine 1999 - 2004)
  • Assistant Professor (Department of Medical Microbiology and Immunology, College of Medicine 1994 - 1999)
  • Adjunct Assistant Professor (Dept. of Biology, Georgia State University 1992 - 1994)
  • Supervisory Research Microbiologist (Viral and Rickettsial Zoonoses Branch, Centers for Disease Control 1984 - 1994)
  • Microbiologist (Staphylococcus and Streptococcus Unit and Sexually Transmitted Diseases Lab Program, Centers for Disease Control 1980 - 1984)

Awards/Honors

  • BACP (Bacterial Pathogenesis) Study Section (NIH - 2014)
  • BACP (Bacterial Pathogenesis) Study Section (NIH - 2013)
  • BACP (Bacterial Pathogenesis) Study Section (NIH - 2012)
  • President's Award for Faculty Excellence (USF - 2003)