Evidence-Based Medicine

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BenjaminDjulbegovic

Benjamin Djulbegovic, MD DSC

Distinguished Univ. Professor, College Of Medicine Internal Medicine

Professor, College Of Medicine Internal Medicine

Professor, Department Of Oncologic Sciences

College Of Medicine Internal Medicine

Director, Evidence-based Medicine Research Group, H. Lee Moffitt Cancer Center & Research Institute, University of South Florida

Director, USF Center for Evidence-based Medicine and Health Outcome Research, University of South Florida

Distinguished Professor, Internal Medicine, Morsani College of Medicine, University of South Florida

Professor, Medicine and Oncology, University of South Florida

Contact Info Division of Evidence Based Medicine
3515 East Fletcher Avenue, MDC 27
Tampa, FL 33612

Academic Email: bdjulbeg@health.usf.edu

Academic Phone: (813) 396-9178

View My C.V.

Education

  • DSC, University Of Sarajevo, 1987
  • M.Sc., Biophysics, University of Zagreb, 1980
  • MD, University Of Sarajevo, 1976

Research Interests

  • Benjamin Djulbegovic is a Distinguished Professor and Professor of Medicine and Oncology at the University of South Florida. His major academic research interest lies in the area of evidence-based medicine, decision-analysis, clinical reasoning, systematic reviews /meta-analysis and comparative effectiveness research, ethics and design of clinical trials, practice guidelines, outcomes research, impact of clinical trials and the role of uncertainty in medicine. He has extensively published and taught on these subjects. His work on regret in decision-making and the role of uncertainty in the conduct of clinical trials received national and international rewards and has received attention of the press all over the world. Dr. Djulbegovic’s research has been funded both by private entities and the NIH (he has been continuously awarded multiple R01 grants- the most prestigious and competitive federal grants- during last 10 years).

Memberships

  • American College of Physicians (Member, 2008 - Present)
  • American Society of Hematology (Member, 2008 - Present)
  • American Society of Clinical Oncology (Member, 2008 - Present)
  • American Medical Association (Member, 2008 - Present)
  • Society for Medical Decision Making (Member, 2008 - Present)
  • Jefferson County Medical Society (Member, 2008 - Present)
  • Florida Medical Association (Member, 2008 - Present)
  • American Association for the Advancement of Science (Member, 2008 - Present)

Recent Publications

  • Djulbegovic, B.Hozo, I.Ioannidis, JP. Improving the drug development process: more not less randomized trials. JAMA : the journal of the American Medical Association. 311(4) : 355-6, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24449311
  • Reljic, T.Mahony, H.Djulbegovic, B.Etchason, J.Paxton, H.Flores, M.Kumar, A. Value of repeat head computed tomography after traumatic brain injury: systematic review and meta-analysis. Journal of neurotrauma. 31(1) : 78-98, 2014. http://www.ncbi.nlm.nih.gov/pubmed/23914924
  • Chalmers, I.Bracken, MB.Djulbegovic, B.Garattini, S.Grant, J.Gülmezoglu, AM.Howells, DW.Ioannidis, JP.Oliver, S. How to increase value and reduce waste when research priorities are set. Lancet. 383(9912) : 156-65, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24411644
  • Alexander, PE.Bero, L.Montori, VM.Brito, JP.Stoltzfus, R.Djulbegovic, B.Neumann, I.Rave, S.Guyatt, G. World Health Organization recommendations are often strong based on low confidence in effect estimates. Journal of clinical epidemiology. , 2014. http://www.ncbi.nlm.nih.gov/pubmed/24388966
  • Mhaskar, RS.Reljic, T.Wao, H.Kumar, A.Miladinovic, B.Djulbegovic, B. Treatment-related harms: What was planned and what was reported? National Cancer Institute's Co-operative group phase III randomized controlled trials: a systematic review. Journal of clinical epidemiology. , 2013. http://www.ncbi.nlm.nih.gov/pubmed/24055164
  • Mhaskar, R.B Bercu, B.Djulbegovic, B. At what level of collective equipoise does a randomized clinical trial become ethical for the members of institutional review board/ethical committees? Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : časopis Društva za medicinsku informatiku BiH. 21(3) : 156-9, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24167382
  • Hernandez, JM.Tsalatsanis, A.Humphries, LA.Miladinovic, B.Djulbegovic, B.Velanovich, V. Defining Optimum Treatment of Patients With Pancreatic Adenocarcinoma Using Regret-Based Decision Curve Analysis. Annals of surgery. , 2013. http://www.ncbi.nlm.nih.gov/pubmed/24169177
  • Patel, J.Ho, M.Ho, V.Bello, C.Djulbegovic, B.Sokol, L.Wetzstein, G. Rapid infusion rituximab for maintenance therapy: is it feasible? Leukemia research and treatment. 2013: 629283, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24288618
  • Miladinovic, B.Mhaskar, R.Kumar, A.Kim, S.Schonwetter, R.Djulbegovic, B. External validation of a web-based prognostic tool for predicting survival for patients in hospice care. Journal of palliative care. 29(3) : 140-6, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24380212
  • Guyatt, GH.Oxman, AD.Santesso, N.Helfand, M.Vist, G.Kunz, R.Brozek, J.Norris, S.Meerpohl, J.Djulbegovic, B.Alonso-Coello, P.Post, PN.Busse, JW.Glasziou, P.Christensen, R.Schünemann, HJ. GRADE guidelines: 12. Preparing summary of findings tables-binary outcomes. Journal of clinical epidemiology. 66(2) : 158-72, 2013. http://www.ncbi.nlm.nih.gov/pubmed/22609141
  • Terasawa, T.Trikalinos, NA.Djulbegovic, B.Trikalinos, TA. Comparative efficacy of first-line therapies for advanced-stage chronic lymphocytic leukemia: a multiple-treatment meta-analysis. Cancer treatment reviews. 39(4) : 340-9, 2013. http://www.ncbi.nlm.nih.gov/pubmed/22703832
  • Miladinovic, B.Kumar, A.Hozo, I.Mahony, H.Djulbegovic, B. Trial sequential analysis may be insufficient to draw firm conclusions regarding statistically significant treatment differences using observed intervention effects: a case study of meta-analyses of multiple myeloma trials. Contemporary clinical trials. 34(2) : 257-61, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23274403
  • Djulbegovic, B.Norris, LB.Bennett, CL. Colony-stimulating factors for febrile neutropenia. The New England journal of medicine. 369(3) : 286, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23863062
  • Baz, R.Miladinovic, B.Patel, A.Ho, VQ.Shain, KH.Alsina, M.Nishihori, T.Ochoa-Bayona, JL.Sullivan, DM.Dalton, WS.Djulbegovic, B. Sequence of novel agents in multiple myeloma: an instrumental variable analysis. Leukemia research. 37(9) : 1077-82, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23809054
  • Ioannidis, JP.Hozo, I.Djulbegovic, B. Optimal type I and type II error pairs when the available sample size is fixed. Journal of clinical epidemiology. 66(8) : 903-910.e2, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23664493
  • El-Jurdi, N.Reljic, T.Kumar, A.Pidala, J.Bazarbachi, A.Djulbegovic, B.Kharfan-Dabaja, MA. Efficacy of adoptive immunotherapy with donor lymphocyte infusion in relapsed lymphoid malignancies. Immunotherapy. 5(5) : 457-66, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23638742
  • Andrews, JC.Schünemann, HJ.Oxman, AD.Pottie, K.Meerpohl, JJ.Coello, PA.Rind, D.Montori, VM.Brito, JP.Norris, S.Elbarbary, M.Post, P.Nasser, M.Shukla, V.Jaeschke, R.Brozek, J.Djulbegovic, B.Guyatt, G. GRADE guidelines: 15. Going from evidence to recommendation-determinants of a recommendation's direction and strength. Journal of clinical epidemiology. 66(7) : 726-35, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23570745
  • Djulbegovic, B.Kumar, A.Miladinovic, B.Reljic, T.Galeb, S.Mhaskar, A.Mhaskar, R.Hozo, I.Tu, D.Stanton, HA.Booth, CM.Meyer, RM. Treatment success in cancer: industry compared to publicly sponsored randomized controlled trials. PloS one. 8(3) : e58711, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23555593
  • Bennett, CL.Djulbegovic, B.Norris, LB.Armitage, JO. Colony-stimulating factors for febrile neutropenia during cancer therapy. The New England journal of medicine. 368(12) : 1131-9, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23514290
  • Wao, H.Mhaskar, R.Kumar, A.Miladinovic, B.Djulbegovic, B. Survival of patients with non-small cell lung cancer without treatment: a systematic review and meta-analysis. Systematic reviews. 2: 10, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23379753
  • Mann, H.Djulbegovic, B. Comparator bias: why comparisons must address genuine uncertainties. Journal of the Royal Society of Medicine. 106(1) : 30-3, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23358277
  • Anderson, KC.Alsina, M.Bensinger, W.Biermann, JS.Cohen, AD.Devine, S.Djulbegovic, B.Faber, EA.Gasparetto, C.Hernandez-Illizaliturri, F.Huff, CA.Kassim, A.Krishnan, AY.Liedtke, M.Meredith, R.Raje, N.Schriber, J.Singhal, S.Somlo, G.Stockerl-Goldstein, K.Treon, SP.Weber, D.Yahalom, J.Yunus, F.Shead, DA.Kumar, R. Multiple myeloma, version 1.2013. Journal of the National Comprehensive Cancer Network : JNCCN. 11(1) : 11-7, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23307977
  • Miladinovic, B.Mhaskar, R.Hozo, I.Kumar, A.Mahony, H.Djulbegovic, B. Optimal information size in trial sequential analysis of time-to-event outcomes reveals potentially inconclusive results because of the risk of random error. Journal of clinical epidemiology. 66(6) : 654-9, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23403248
  • Kharfan-Dabaja, MA.Hamadani, M.Reljic, T.Nishihori, T.Bensinger, W.Djulbegovic, B.Kumar, A. Comparative efficacy of tandem autologous versus autologous followed by allogeneic hematopoietic cell transplantation in patients with newly diagnosed multiple myeloma: a systematic review and meta-analysis of randomized controlled trials. Journal of hematology & oncology. 6: 2, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23289975
  • Djulbegovic, B.Kumar, A.Glasziou, P.Miladinovic, B.Chalmers, I. Medical research: Trial unpredictability yields predictable therapy gains. Nature. 500(7463) : 395-6, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23969443
  • Mhaskar, R.Alandikar, V.Emmanuel, P.Djulbegovic, B.Patel, S.Patel, A.Naik, E.Mohapatra, S.Kumar, A. Adherence to antiretroviral therapy in India: a systematic review and meta-analysis. Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine. 38(2) : 74-82, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23878418
  • Kharfan-Dabaja, MA.Hamadani, M.Reljic, T.Pyngolil, R.Komrokji, RS.Lancet, JE.Fernandez, HF.Djulbegovic, B.Kumar, A. Gemtuzumab ozogamicin for treatment of newly diagnosed acute myeloid leukaemia: a systematic review and meta-analysis. British journal of haematology. 163(3) : 315-25, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24033280
  • Veenstra, DL.Piper, M.Haddow, JE.Pauker, SG.Klein, R.Richards, CS.Tunis, SR.Djulbegovic, B.Marrone, M.Lin, JS.Berg, AO.Calonge, N. Improving the efficiency and relevance of evidence-based recommendations in the era of whole-genome sequencing: an EGAPP methods update. Genetics in medicine : official journal of the American College of Medical Genetics. 15(1) : 14-24, 2013. http://www.ncbi.nlm.nih.gov/pubmed/22955111
  • Ilic, D.Neuberger, MM.Djulbegovic, M.Dahm, P. Screening for prostate cancer. The Cochrane database of systematic reviews. 1: CD004720, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23440794
  • Gil-Herrera, E.Yalcin, A.Tsalatsanis, A.Barnes, LE.Djulbegovic, B. Towards a classification model to identify hospice candidates in terminally ill patients. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2012: 1278-81, 2012. http://www.ncbi.nlm.nih.gov/pubmed/23366132
  • Djulbegovic, M.Neuberger, MM.Dahm, P. Prostate-cancer mortality after PSA screening. The New England journal of medicine. 366(23) : 2228-9; author reply 2230-1, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22670914
  • Djulbegovic, B.Hozo, I.Beckstead, J.Tsalatsanis, A.Pauker, SG. Dual processing model of medical decision-making. BMC medical informatics and decision making. 12: 94, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22943520
  • Anderson, KC.Alsina, M.Bensinger, W.Biermann, JS.Cohen, AD.Devine, S.Djulbegovic, B.Faber, EA.Gasparetto, C.Hernandez-Ilizaliturri, F.Huff, CA.Kassim, A.Krishnan, AY.Medeiros, BC.Meredith, R.Raje, N.Schriber, J.Singhal, S.Somlo, G.Stockerl-Goldstein, K.Treon, SP.Tricot, G.Weber, DM.Yahalom, J.Yunus, F.Kumar, R.Shead, DA. Waldenström's macroglobulinemia/lymphoplasmacytic lymphoma, version 2.2013. Journal of the National Comprehensive Cancer Network : JNCCN. 10(10) : 1211-9, 2012. http://www.ncbi.nlm.nih.gov/pubmed/23054875
  • Miladinovic, B.Kumar, A.Mhaskar, R.Kim, S.Schonwetter, R.Djulbegovic, B. A flexible alternative to the Cox proportional hazards model for assessing the prognostic accuracy of hospice patient survival. PloS one. 7(10) : e47804, 2012. http://www.ncbi.nlm.nih.gov/pubmed/23082220
  • Djulbegovic, B.Kumar, A.Glasziou, PP.Perera, R.Reljic, T.Dent, L.Raftery, J.Johansen, M.Di Tanna, GL.Miladinovic, B.Soares, HP.Vist, GE.Chalmers, I. New treatments compared to established treatments in randomized trials. The Cochrane database of systematic reviews. 10: MR000024, 2012. http://www.ncbi.nlm.nih.gov/pubmed/23076962
  • Rodgers, GM.Becker, PS.Blinder, M.Cella, D.Chanan-Khan, A.Cleeland, C.Coccia, PF.Djulbegovic, B.Gilreath, JA.Kraut, EH.Matulonis, UA.Millenson, MM.Reinke, D.Rosenthal, J.Schwartz, RN.Soff, G.Stein, RS.Vlahovic, G.Weir, AB. Cancer- and chemotherapy-induced anemia. Journal of the National Comprehensive Cancer Network : JNCCN. 10(5) : 628-53, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22570293
  • Mhaskar, R.Redzepovic, J.Wheatley, K.Clark, OA.Miladinovic, B.Glasmacher, A.Kumar, A.Djulbegovic, B. Bisphosphonates in multiple myeloma: a network meta-analysis. The Cochrane database of systematic reviews. 5: CD003188, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22592688
  • Carson, JL.Grossman, BJ.Kleinman, S.Tinmouth, AT.Marques, MB.Fung, MK.Holcomb, JB.Illoh, O.Kaplan, LJ.Katz, LM.Rao, SV.Roback, JD.Shander, A.Tobian, AA.Weinstein, R.Swinton McLaughlin, LG.Djulbegovic, B. Red Blood Cell Transfusion: A Clinical Practice Guideline From the AABB. Annals of internal medicine. : E-429, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22711030
  • Djulbegovic, B.Hozo, I. When is it rational to participate in a clinical trial? A game theory approach incorporating trust, regret and guilt. BMC medical research methodology. 12: 85, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22726276
  • Carson, JL.Grossman, BJ.Kleinman, S.Tinmouth, AT.Marques, MB.Fung, MK.Holcomb, JB.Illoh, O.Kaplan, LJ.Katz, LM.Rao, SV.Roback, JD.Shander, A.Tobian, AA.Weinstein, R.Swinton McLaughlin, LG.Djulbegovic, B. Red blood cell transfusion: a clinical practice guideline from the AABB*. Annals of internal medicine. 157(1) : 49-58, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22751760
  • Mhaskar, R.Djulbegovic, B.Magazin, A.Soares, HP.Kumar, A. Published methodological quality of randomized controlled trials does not reflect the actual quality assessed in protocols. Journal of clinical epidemiology. 65(6) : 602-9, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22424985
  • Kharfan-Dabaja, MA.Pidala, J.Kumar, A.Terasawa, T.Djulbegovic, B. Comparing efficacy of reduced-toxicity allogeneic hematopoietic cell transplantation with conventional chemo-(immuno) therapy in patients with relapsed or refractory CLL: a Markov decision analysis. Bone marrow transplantation. 47(9) : 1164-70, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22562081
  • Carson, JL.Grossman, BJ.Kleinman, S.Tinmouth, AT.Marques, MB.Fung, MK.Holcomb, JB.Illoh, O.Kaplan, LJ.Katz, LM.Rao, SV.Roback, JD.Shander, A.Tobian, AA.Weinstein, R.Swinton McLaughlin, LG.Djulbegovic, B. Red Blood Cell Transfusion: A Clinical Practice Guideline From the AABB. Annals of internal medicine. , 2012. http://www.ncbi.nlm.nih.gov/pubmed/22454395
  • La Caze, A.Djulbegovic, B.Senn, S. What does randomisation achieve? Evidence-based medicine. 17(1) : 1-2, 2012. http://www.ncbi.nlm.nih.gov/pubmed/21693455
  • Schroen, AT.Petroni, GR.Wang, H.Thielen, MJ.Gray, R.Benedetti, J.Wang, XF.Sargent, DJ.Wickerham, DL.Cronin, W.Djulbegovic, B.Slingluff, CL. Achieving sufficient accrual to address the primary endpoint in phase III clinical trials from U.S. Cooperative Oncology Groups. Clinical cancer research : an official journal of the American Association for Cancer Research. 18(1) : 256-62, 2012. http://www.ncbi.nlm.nih.gov/pubmed/21976533
  • Kumar, A.Mhaskar, AR.Reljic, T.Mhaskar, RS.Kharfan-Dabaja, MA.Anasetti, C.Mohty, M.Djulbegovic, B. Antithymocyte globulin for acute-graft-versus-host-disease prophylaxis in patients undergoing allogeneic hematopoietic cell transplantation: a systematic review. Leukemia. 26(4) : 582-8, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22182922
  • Djulbegovic, M.Djulbegovic, B. Implications of the principle of question propagation for comparative-effectiveness and "data mining" research. JAMA : the journal of the American Medical Association. 305(3) : 298-9, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21245185
  • Kumar, A.Hozo, I.Wheatley, K.Djulbegovic, B. Thalidomide versus bortezomib based regimens as first-line therapy for patients with multiple myeloma: a systematic review. American journal of hematology. 86(1) : 18-24, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21120867
  • Anderson, KC.Alsina, M.Bensinger, W.Biermann, JS.Chanan-Khan, A.Cohen, AD.Devine, S.Djulbegovic, B.Faber, EA.Gasparetto, C.Huff, CA.Kassim, A.Medeiros, BC.Meredith, R.Raje, N.Schriber, J.Singhal, S.Somlo, G.Stockerl-Goldstein, K.Treon, SP.Tricot, G.Weber, DM.Yahalom, J.Yunus, F. Multiple myeloma. Journal of the National Comprehensive Cancer Network : JNCCN. 9(10) : 1146-83, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21975914
  • Pidala, J.Djulbegovic, B.Anasetti, C.Kharfan-Dabaja, M.Kumar, A. Allogeneic hematopoietic cell transplantation for adult acute lymphoblastic leukemia (ALL) in first complete remission. Cochrane database of systematic reviews (Online). (10) : CD008818, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21975786
  • Schroen, AT.Petroni, GR.Wang, H.Thielen, MJ.Sargent, D.Benedetti, JK.Cronin, WM.Wickerham, DL.Wang, XF.Gray, R.Cohn, WF.Slingluff, CL.Djulbegovic, B. Challenges to accrual predictions to phase III cancer clinical trials: a survey of study chairs and lead statisticians of 248 NCI-sponsored trials. Clinical trials (London, England). 8(5) : 591-600, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21878447
  • Djulbegovic, B. Uncertainty and equipoise: at interplay between epistemology, decision making and ethics. The American journal of the medical sciences. 342(4) : 282-9, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21817885
  • Guyatt, GH.Oxman, AD.Montori, V.Vist, G.Kunz, R.Brozek, J.Alonso-Coello, P.Djulbegovic, B.Atkins, D.Falck-Ytter, Y.Williams, JW.Meerpohl, J.Norris, SL.Akl, EA.Schünemann, HJ. GRADE guidelines: 5. Rating the quality of evidence--publication bias. Journal of clinical epidemiology. 64(12) : 1277-82, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21802904
  • Kumar, A.Galeb, S.Djulbegovic, B. Treatment of patients with multiple myeloma: an overview of systematic reviews. Acta haematologica. 125(1-2) : 8-22, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21150183
  • Djulbegovic, B.Paul, A. From efficacy to effectiveness in the face of uncertainty: indication creep and prevention creep. JAMA : the journal of the American Medical Association. 305(19) : 2005-6, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21586716
  • Miladinovic, B.Kumar, A.Hozo, I.Djulbegovic, B. Instrumental variable meta-analysis of individual patient data: application to adjust for treatment non-compliance. BMC medical research methodology. 11: 55, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21510899
  • Tsalatsanis, A.Barnes, L.Hozo, I.Skvoretz, J.Djulbegovic, B. A social network analysis of treatment discoveries in cancer. PloS one. 6(3) : e18060, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21464896
  • Dahm, P.Djulbegovic, B. The Australian 'FORM' approach to guideline development: the quest for the perfect system. BMC medical research methodology. 11: 17, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21324126
  • Guyatt, GH.Oxman, AD.Vist, G.Kunz, R.Brozek, J.Alonso-Coello, P.Montori, V.Akl, EA.Djulbegovic, B.Falck-Ytter, Y.Norris, SL.Williams, JW.Atkins, D.Meerpohl, J.Schünemann, HJ. GRADE guidelines: 4. Rating the quality of evidence--study limitations (risk of bias). Journal of clinical epidemiology. 64(4) : 407-15, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21247734
  • Tsalatsanis, A.Barnes, LE.Hozo, I.Djulbegovic, B. Extensions to Regret-based Decision Curve Analysis: An application to hospice referral for terminal patients. BMC medical informatics and decision making. 11(1) : 77, 2011. http://www.ncbi.nlm.nih.gov/pubmed/22196308
  • Tsalatsanis, A.Gil-Herrera, E.Yalcin, A.Djulbegovic, B.Barnes, L. Designing patient-centric applications for chronic disease management. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2011: 3146-9, 2011. http://www.ncbi.nlm.nih.gov/pubmed/22255007
  • Gil-Herrera, E.Yalcin, A.Tsalatsanis, A.Barnes, LE.Djulbegovic, B. Rough Set Theory based prognostication of life expectancy for terminally ill patients. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2011: 6438-41, 2011. http://www.ncbi.nlm.nih.gov/pubmed/22255812
  • Djulbegovic, B.Kumar, A.Magazin, A.Schroen, AT.Soares, H.Hozo, I.Clarke, M.Sargent, D.Schell, MJ. Optimism bias leads to inconclusive results-an empirical study. Journal of clinical epidemiology. 64(6) : 583-93, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21163620
  • Herold, CI.Djulbegovic, B.Hozo, I.Lyman, GH. Reliable data on 5- and 10-year survival provide accurate estimates of 15-year survival in estrogen receptor-positive early-stage breast cancer. Breast cancer research and treatment. 121(3) : 771-6, 2010. http://www.ncbi.nlm.nih.gov/pubmed/19806449
  • Wager, E.Mhaskar, R.Warburton, S.Djulbegovic, B. JAMA published fewer industry-funded studies after introducing a requirement for independent statistical analysis. PloS one. 5(10) : e13591, 2010. http://www.ncbi.nlm.nih.gov/pubmed/21042585
  • Tsalatsanis, A.Hozo, I.Vickers, A.Djulbegovic, B. A regret theory approach to decision curve analysis: a novel method for eliciting decision makers' preferences and decision-making. BMC medical informatics and decision making. 10: 51, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20846413
  • Djulbegovic, M.Beyth, RJ.Neuberger, MM.Stoffs, TL.Vieweg, J.Djulbegovic, B.Dahm, P. Screening for prostate cancer: systematic review and meta-analysis of randomised controlled trials. BMJ (Clinical research ed.). 341: c4543, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20843937
  • Schroen, AT.Petroni, GR.Wang, H.Gray, R.Wang, XF.Cronin, W.Sargent, DJ.Benedetti, J.Wickerham, DL.Djulbegovic, B.Slingluff, CL. Preliminary evaluation of factors associated with premature trial closure and feasibility of accrual benchmarks in phase III oncology trials. Clinical trials (London, England). 7(4) : 312-21, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20595245
  • Djulbegovic, B. Management of venous Thromboembolism in cancer: a brief review of risk-benefit approaches and guidelines' recommendations. The journal of supportive oncology. 8(2) : 84-91, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20464888
  • Mhaskar, AR.Quinn, G.Vadaparampil, S.Djulbegovic, B.Gwede, CK.Kumar, A. Timing of first-line cancer treatments - early versus late - a systematic review of phase III randomized trials. Cancer treatment reviews. 36(8) : 621-8, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20444550
  • Roback, JD.Caldwell, S.Carson, J.Davenport, R.Drew, MJ.Eder, A.Fung, M.Hamilton, M.Hess, JR.Luban, N.Perkins, JG.Sachais, BS.Shander, A.Silverman, T.Snyder, E.Tormey, C.Waters, J.Djulbegovic, B. Evidence-based practice guidelines for plasma transfusion. Transfusion. 50(6) : 1227-39, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20345562
  • Bassler, D.Briel, M.Montori, VM.Lane, M.Glasziou, P.Zhou, Q.Heels-Ansdell, D.Walter, SD.Guyatt, GH.Flynn, DN.Elamin, MB.Murad, MH.Abu Elnour, NO.Lampropulos, JF.Sood, A.Mullan, RJ.Erwin, PJ.Bankhead, CR.Perera, R.Ruiz Culebro, C.You, JJ.Mulla, SM.Kaur, J.Nerenberg, KA.Schünemann, H.Cook, DJ.Lutz, K.Ribic, CM.Vale, N.Malaga, G.Akl, EA.Ferreira-Gonzalez, I.Alonso-Coello, P.Urrutia, G.Kunz, R.Bucher, HC.Nordmann, AJ.Raatz, H.da Silva, SA.Tuche, F.Strahm, B.Djulbegovic, B.Adhikari, NK.Mills, EJ.Gwadry-Sridhar, F.Kirpalani, H.Soares, HP.Karanicolas, PJ.Burns, KE.Vandvik, PO.Coto-Yglesias, F.Chrispim, PP.Ramsay, T. Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis. JAMA : the journal of the American Medical Association. 303(12) : 1180-7, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20332404
  • Mhaskar, R.Redzepovic, J.Wheatley, K.Clark, OA.Miladinovic, B.Glasmacher, A.Kumar, A.Djulbegovic, B. Bisphosphonates in multiple myeloma. Cochrane database of systematic reviews (Online). (3) : CD003188, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20238320
  • Kumar, A.List, AF.Hozo, I.Komrokji, R.Djulbegovic, B. Decitabine versus 5-azacitidine for the treatment of myelodysplastic syndrome: adjusted indirect meta-analysis. Haematologica. 95(2) : 340-2; author reply 343-4, 2010. http://www.ncbi.nlm.nih.gov/pubmed/19850902
  • Djulbegovic, B. Risk prediction versus diagnosis: preserving clinical nuance in a binary world. Annals of internal medicine. 150(3) : 223; author reply 224, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19189922
  • Bohlius, J.Schmidlin, K.Brillant, C.Schwarzer, G.Trelle, S.Seidenfeld, J.Zwahlen, M.Clarke, M.Weingart, O.Kluge, S.Piper, M.Rades, D.Steensma, DP.Djulbegovic, B.Fey, MF.Ray-Coquard, I.Machtay, M.Moebus, V.Thomas, G.Untch, M.Schumacher, M.Egger, M.Engert, A. Recombinant human erythropoiesis-stimulating agents and mortality in patients with cancer: a meta-analysis of randomised trials. Lancet. 373(9674) : 1532-42, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19410717
  • Pidala, J.Anasetti, C.Kharfan-Dabaja, MA.Cutler, C.Sheldon, A.Djulbegovic, B. Decision analysis of peripheral blood versus bone marrow hematopoietic stem cells for allogeneic hematopoietic cell transplantation. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 15(11) : 1415-21, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19822301
  • Kharfan-Dabaja, MA.Mhaskar, AR.Djulbegovic, B.Cutler, C.Mohty, M.Kumar, A. Efficacy of rituximab in the setting of steroid-refractory chronic graft-versus-host disease: a systematic review and meta-analysis. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 15(9) : 1005-13, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19660713
  • Djulbegovic, B.Trikalinos, TA.Roback, J.Chen, R.Guyatt, G. Impact of quality of evidence on the strength of recommendations: an empirical study. BMC health services research. 9: 120, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19622148
  • Goy, A.Bernstein, SH.Kahl, BS.Djulbegovic, B.Robertson, MJ.de Vos, S.Epner, E.Krishnan, A.Leonard, JP.Lonial, S.Nasta, S.O'Connor, OA.Shi, H.Boral, AL.Fisher, RI. Bortezomib in patients with relapsed or refractory mantle cell lymphoma: updated time-to-event analyses of the multicenter phase 2 PINNACLE study. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 20(3) : 520-5, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19074748
  • Djulbegovic, B. The paradox of equipoise: the principle that drives and limits therapeutic discoveries in clinical research. Cancer control : journal of the Moffitt Cancer Center. 16(4) : 342-7, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19910921
  • Anderson, KC.Alsina, M.Bensinger, W.Biermann, JS.Chanan-Khan, A.Cohen, AD.Devine, S.Djulbegovic, B.Gasparetto, C.Huff, CA.Jagasia, M.Medeiros, BC.Meredith, R.Raje, N.Schriber, J.Singhal, S.Somlo, G.Stockerl-Goldstein, K.Tricot, G.Vose, JM.Weber, D.Yahalom, J.Yunus, F. NCCN clinical practice guidelines in oncology: multiple myeloma. Journal of the National Comprehensive Cancer Network : JNCCN. 7(9) : 908-42, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19878637
  • Freedman A, Neelapu S, Nichols C, Robertson M, Djulbegovic B, et.al. A Placebo-Controlled Phase III Trial of Patient-Specific Immunotherapy with Mitumprotimut-T and GM-CSF Following Rituximab in Patients with Follicular Lymphoma. J Clin Oncol. : In Press, 2009.
  • Djulbegovic B, Guyatt G, Ashcroft R. Epistemological Inquiries in Evidence Based Medicine. Cancer Control. : In Press, 2009.
  • Kumar, A.Kharfan-Dabaja, MA.Glasmacher, A.Djulbegovic, B. Tandem versus single autologous hematopoietic cell transplantation for the treatment of multiple myeloma: a systematic review and meta-analysis. Journal of the National Cancer Institute. 101(2) : 100-6, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19141779
  • Mhaskar, R.Kumar, A.Behera, M.Kharfan-Dabaja, MA.Djulbegovic, B. Role of high-dose chemotherapy and autologous hematopoietic cell transplantation in primary systemic amyloidosis: a systematic review. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 15(8) : 893-902, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19589478
  • Bohlius, J.Schmidlin, K.Brillant, C.Schwarzer, G.Trelle, S.Seidenfeld, J.Zwahlen, M.Clarke, MJ.Weingart, O.Kluge, S.Piper, M.Napoli, M.Rades, D.Steensma, D.Djulbegovic, B.Fey, MF.Ray-Coquard, I.Moebus, V.Thomas, G.Untch, M.Schumacher, M.Egger, M.Engert, A. Erythropoietin or Darbepoetin for patients with cancer--meta-analysis based on individual patient data. Cochrane database of systematic reviews (Online). (3) : CD007303, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19588423
  • Briel, M.Lane, M.Montori, VM.Bassler, D.Glasziou, P.Malaga, G.Akl, EA.Ferreira-Gonzalez, I.Alonso-Coello, P.Urrutia, G.Kunz, R.Culebro, CR.da Silva, SA.Flynn, DN.Elamin, MB.Strahm, B.Murad, MH.Djulbegovic, B.Adhikari, NK.Mills, EJ.Gwadry-Sridhar, F.Kirpalani, H.Soares, HP.Abu Elnour, NO.You, JJ.Karanicolas, PJ.Bucher, HC.Lampropulos, JF.Nordmann, AJ.Burns, KE.Mulla, SM.Raatz, H.Sood, A.Kaur, J.Bankhead, CR.Mullan, RJ.Nerenberg, KA.Vandvik, PO.Coto-Yglesias, F.Schünemann, H.Tuche, F.Chrispim, PP.Cook, DJ.Lutz, K.Ribic, CM.Vale, N.Erwin, PJ.Perera, R.Zhou, Q.Heels-Ansdell, D.Ramsay, T.Walter, SD.Guyatt, GH. Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2). Trials. 10: 49, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19580665
  • Koreth, J.Schlenk, R.Kopecky, KJ.Honda, S.Sierra, J.Djulbegovic, BJ.Wadleigh, M.DeAngelo, DJ.Stone, RM.Sakamaki, H.Appelbaum, FR.Döhner, H.Antin, JH.Soiffer, RJ.Cutler, C. Allogeneic stem cell transplantation for acute myeloid leukemia in first complete remission: systematic review and meta-analysis of prospective clinical trials. JAMA : the journal of the American Medical Association. 301(22) : 2349-61, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19509382
  • Dorr, DA.Burdon, R.West, DP.Lagman, J.Georgopoulos, C.Belknap, SM.McKoy, JM.Djulbegovic, B.Edwards, BJ.Weitzman, SA.Boyle, S.Tallman, MS.Talpaz, M.Sartor, O.Bennett, CL. Quality of reporting of serious adverse drug events to an institutional review board: a case study with the novel cancer agent, imatinib mesylate. Clinical cancer research : an official journal of the American Association for Cancer Research. 15(11) : 3850-5, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19458059
  • Freedman, A.Neelapu, SS.Nichols, C.Robertson, MJ.Djulbegovic, B.Winter, JN.Bender, JF.Gold, DP.Ghalie, RG.Stewart, ME.Esquibel, V.Hamlin, P. Placebo-controlled phase III trial of patient-specific immunotherapy with mitumprotimut-T and granulocyte-macrophage colony-stimulating factor after rituximab in patients with follicular lymphoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 27(18) : 3036-43, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19414675
  • Djulbegovic, B.Guyatt, GH.Ashcroft, RE. Epistemologic inquiries in evidence-based medicine. Cancer control : journal of the Moffitt Cancer Center. 16(2) : 158-68, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19337202
  • Rizzo JD, Somerfield MR, Hagerty KL,Seidenfeld J, Bohlius J, Bennett CL, Cella DF, Djulbegovic B, Goode M, Jakubowski AA, Rarick MU, Regan DH, Lichtin AE. American Society of Clinical Oncology/American Society Of Hematology 2007 Clinical Practice Guideline Update on the Use of Epoetin And Darbepoetin. J Clin Oncol. 26: 132-149, 2008.
  • Djulbegovic B, Kumar A, , Bepler G, Clarke M, Soares HP, Hozo I, Bennett CL. Treatment success in cancer-reply. Arch Intern Med. 168: 2173-2174, 2008.
  • Djulbegovic, B. Evidence-Based Medicine: In Its Place. Medical decision making : an international journal of the Society for Medical Decision Making. , 2008. http://www.ncbi.nlm.nih.gov/pubmed/18270305
  • Rizzo, JD.Somerfield, MR.Hagerty, KL.Seidenfeld, J.Bohlius, J.Bennett, CL.Cella, DF.Djulbegovic, B.Goode, MJ.Jakubowski, AA.Rarick, MU.Regan, DH.Lichtin, AE. Use of epoetin and darbepoetin in patients with cancer: 2007 American Society of Hematology/American Society of Clinical Oncology clinical practice guideline update. Blood. 111(1) : 25-41, 2008. http://www.ncbi.nlm.nih.gov/pubmed/17954703
  • Rizzo, JD.Somerfield, MR.Hagerty, KL.Seidenfeld, J.Bohlius, J.Bennett, CL.Cella, DF.Djulbegovic, B.Goode, MJ.Jakubowski, AA.Rarick, MU.Regan, DH.Lichtin, AE. Use of epoetin and darbepoetin in patients with cancer: 2007 American Society of Clinical Oncology/American Society of Hematology clinical practice guideline update. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 26(1) : 132-49, 2008. http://www.ncbi.nlm.nih.gov/pubmed/17954713
  • Wilcox, RA.Djulbegovic, B.Moffitt, HL.Guyatt, GH.Montori, VM. Randomized trials in oncology stopped early for benefit. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 26(1) : 18-9, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18165635
  • Fletcher, JW.Djulbegovic, B.Soares, HP.Siegel, BA.Lowe, VJ.Lyman, GH.Coleman, RE.Wahl, R.Paschold, JC.Avril, N.Einhorn, LH.Suh, WW.Samson, D.Delbeke, D.Gorman, M.Shields, AF. Recommendations on the use of 18F-FDG PET in oncology. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 49(3) : 480-508, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18287273
  • Bennett, CL.Silver, SM.Djulbegovic, B.Samaras, AT.Blau, CA.Gleason, KJ.Barnato, SE.Elverman, KM.Courtney, DM.McKoy, JM.Edwards, BJ.Tigue, CC.Raisch, DW.Yarnold, PR.Dorr, DA.Kuzel, TM.Tallman, MS.Trifilio, SM.West, DP.Lai, SY.Henke, M. Venous thromboembolism and mortality associated with recombinant erythropoietin and darbepoetin administration for the treatment of cancer-associated anemia. JAMA : the journal of the American Medical Association. 299(8) : 914-24, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18314434
  • Djulbegovic, B.Kumar, A.Soares, HP.Hozo, I.Bepler, G.Clarke, M.Bennett, CL. Treatment success in cancer: new cancer treatment successes identified in phase 3 randomized controlled trials conducted by the National Cancer Institute-sponsored cooperative oncology groups, 1955 to 2006. Archives of internal medicine. 168(6) : 632-42, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18362256
  • Hozo, I.Djulbegovic, B. When is diagnostic testing inappropriate or irrational? Acceptable regret approach. Medical decision making : an international journal of the Society for Medical Decision Making. 28(4) : 540-53, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18480041
  • Djulbegovic, B.Kumar, A. Multiple myeloma: detecting the effects of new treatments. Lancet. 371(9625) : 1642-4, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18486726
  • Hozo, I.Schell, MJ.Djulbegovic, B. Decision-making when data and inferences are not conclusive: risk-benefit and acceptable regret approach. Seminars in hematology. 45(3) : 150-9, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18582621
  • Kunz, R.Djulbegovic, B.Schunemann, HJ.Stanulla, M.Muti, P.Guyatt, G. Misconceptions, challenges, uncertainty, and progress in guideline recommendations. Seminars in hematology. 45(3) : 167-75, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18582623
  • Rodgers, GM.Becker, PS.Bennett, CL.Cella, D.Chanan-Khan, A.Chesney, C.Cleeland, C.Coccia, PF.Djulbegovic, B.Garst, JL.Gilreath, JA.Kraut, EH.Lin, WC.Matulonis, U.Millenson, M.Reinke, D.Rosenthal, J.Sabbatini, P.Schwartz, RN.Stein, RS.Vij, R. Cancer- and chemotherapy-induced anemia. Journal of the National Comprehensive Cancer Network : JNCCN. 6(6) : 536-64, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18597709
  • Hoppe, RT.Advani, RH.Ambinder, RF.Bierman, PJ.Bloomfield, CD.Blum, K.Dabaja, B.Djulbegovic, B.Forero, A.Gordon, LI.Hernandez-Ilizaliturri, FJ.Hudson, MM.Kaminski, MS.Love, G.Maloney, DG.Mansur, D.Mauch, PM.Moore, JO.Schilder, RJ.Weiss, LM.Winter, JN.Yahalom, J.Zelenetz, AD. Hodgkin disease/lymphoma. Journal of the National Comprehensive Cancer Network : JNCCN. 6(6) : 594-622, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18597713
  • Soares, HP.Kumar, A.Djulbegovic, B. Evidence profiles for breast cancer: benefit/harms data based on the totality of randomized evidence. Cancer treatment reviews. 33(1) : 87-9, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17081695
  • Tanvetyanon, T.Soares, HP.Djulbegovic, B.Jacobsen, PB.Bepler, G. A systematic review of quality of life associated with standard chemotherapy regimens for advanced non-small cell lung cancer. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2(12) : 1091-7, 2007. http://www.ncbi.nlm.nih.gov/pubmed/18090580
  • Koreth, J.Cutler, CS.Djulbegovic, B.Behl, R.Schlossman, RL.Munshi, NC.Richardson, PG.Anderson, KC.Soiffer, RJ.Alyea, EP. High-dose therapy with single autologous transplantation versus chemotherapy for newly diagnosed multiple myeloma: A systematic review and meta-analysis of randomized controlled trials. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 13(2) : 183-96, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17241924
  • Djulbegovic, B.Hozo, I. When should potentially false research findings be considered acceptable? PLoS medicine. 4(2) : e26, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17326703
  • Anderson, KC.Alsina, M.Bensinger, W.Biermann, JS.Chanan-Khan, A.Comenzo, RL.De Castro, CM.Djulbegovic, B.Farag, S.Huff, CA.Meredith, R.Schriber, J.Shrieve, D.Singhal, S.Smith, MR.Stockerl-Goldstein, K.Vose, JM.Weber, D.Yahalom, J.Yunus, F. Multiple myeloma. Clinical practice guidelines in oncology. Journal of the National Comprehensive Cancer Network : JNCCN. 5(2) : 118-47, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17335683
  • Behera, M.Kumar, A.Soares, HP.Sokol, L.Djulbegovic, B. Evidence-based medicine for rare diseases: implications for data interpretation and clinical trial design. Cancer control : journal of the Moffitt Cancer Center. 14(2) : 160-6, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17387301
  • Djulbegovic, B.Hozo, I.Lyman, GH. Estimating net benefits and harms of screening mammography in women age 40 to 49 years. Annals of internal medicine. 147(12) : 882, 2007. http://www.ncbi.nlm.nih.gov/pubmed/18087062
  • Scheetz, MH.McKoy, JM.Parada, JP.Djulbegovic, B.Raisch, DW.Yarnold, PR.Zagory, J.Trifilio, S.Jakiche, R.Palella, F.Kahn, A.Chandler, K.Bennett, CL. Systematic review of piperacillin-induced neutropenia. Drug safety : an international journal of medical toxicology and drug experience. 30(4) : 295-306, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17408306
  • Djulbegovic, B. Articulating and responding to uncertainties in clinical research. The Journal of medicine and philosophy. 32(2) : 79-98, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17454416
  • Bennett, CL.Nebeker, JR.Yarnold, PR.Tigue, CC.Dorr, DA.McKoy, JM.Edwards, BJ.Hurdle, JF.West, DP.Lau, DT.Angelotta, C.Weitzman, SA.Belknap, SM.Djulbegovic, B.Tallman, MS.Kuzel, TM.Benson, AB.Evens, A.Trifilio, SM.Courtney, DM.Raisch, DW. Evaluation of serious adverse drug reactions: a proactive pharmacovigilance program (RADAR) vs safety activities conducted by the Food and Drug Administration and pharmaceutical manufacturers. Archives of internal medicine. 167(10) : 1041-9, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17533207
  • Djulbegovic, B.Angelotta, C.Knox, KE.Bennett, CL. The sound and the fury: financial conflicts of interest in oncology. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 25(24) : 3567-9, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17704401
  • Kharfan-Dabaja, MA.Kumar, A.Behera, M.Djulbegovic, B. Systematic review of high dose chemotherapy and autologous haematopoietic stem cell transplantation for chronic lymphocytic leukaemia: what is the published evidence? British journal of haematology. 139(2) : 234-42, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17897299
  • Kumar, A.Soares, HP.Balducci, L.Djulbegovic, B. Treatment tolerance and efficacy in geriatric oncology: a systematic review of phase III randomized trials conducted by five National Cancer Institute-sponsored cooperative groups. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 25(10) : 1272-6, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17401017
  • Kumar, A.Djulbegovic, B. Myeloma (multiple). Clinical evidence. (15) : 1-29, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16973003
  • Fisher, RI.Bernstein, SH.Kahl, BS.Djulbegovic, B.Robertson, MJ.de Vos, S.Epner, E.Krishnan, A.Leonard, JP.Lonial, S.Stadtmauer, EA.O'Connor, OA.Shi, H.Boral, AL.Goy, A. Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 24(30) : 4867-74, 2006. http://www.ncbi.nlm.nih.gov/pubmed/17001068
  • Stem Cell Trialists Group (Principal Investigator: Djulbegovic B). Individual patient data meta-analysis of allogeneic peripheral blood stem cell transplant vs. bone marrow transplant in the management of hematological malignancies: indirect assessment of the effect of day 11 methotrexate administration. Bone Marrow Transplant. 38: 539-546, 2006.
  • Kumar, A.Soares, HP.Djulbegovic, B. Evidence profiles for colo-rectal cancer: benefit/harms data based on the totality of randomized evidence. Cancer treatment reviews. 32(7) : 577-80, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16919883
  • Djulbegovic, B.Soares, HP.Kumar, A. What kind of evidence do patients and practitioners need: evidence profiles based on 5 key evidence-based principles to summarize data on benefits and harms. Cancer treatment reviews. 32(7) : 572-6, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16914268
  • Bohlius, J.Wilson, J.Seidenfeld, J.Piper, M.Schwarzer, G.Sandercock, J.Trelle, S.Weingart, O.Bayliss, S.Brunskill, S.Djulbegovic, B.Benett, CL.Langensiepen, S.Hyde, C.Engert, E. Erythropoietin or darbepoetin for patients with cancer. Cochrane database of systematic reviews (Online). 3: CD003407, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16856007
  • Glasziou, P.Djulbegovic, B.Burls, A. Are systematic reviews more cost-effective than randomised trials? Lancet. 367(9528) : 2057-8, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16798380
  • Djulbegovic, B. Evidence and decision making. Commentary on M.R. Tonelli (2006), Integrating evidence into clinical practice: an alternative approach to evidence-based approaches. Journal of Evaluation in Clinical Practice 12, 248-256. Journal of evaluation in clinical practice. 12(3) : 257-9, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16722903
  • Pavlidis, N.Stahel, R.Clarke, M.Djulbegovic, B. Cancer treatment reviews welcomes submission of the Cochrane Reviews. Cancer treatment reviews. 32(4) : 243-4, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16713102
  • Djulbegovic, B.Bickerdike, L. High-quality evidence in oncology from 3 November to 24 November, 2005: a summary. Cancer treatment reviews. 32(3) : 239-41, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16624491
  • Djulbegovic, B.Bickerdike, L. High-quality evidence in oncology from 16 June to 18 August 2005: a summary. Cancer treatment reviews. 32(1) : 59-64, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16434143
  • Djulbegovic, B.Bickerdike, L. High-quality evidence in oncology from 25 August to 27 October 2005: A summary. Cancer treatment reviews. 32(2) : 149-55, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16520003
  • Soares, HP.Kumar, A.Djulbegovic, B. Evidence profiles for lung cancer: benefit/harms data based on the totality of randomized evidence. Cancer treatment reviews. 32(8) : 652-5, 2006. http://www.ncbi.nlm.nih.gov/pubmed/17008011
  • Hoppe RT. Advani RH. Bierman PJ. Bloomfield CD. Buadi F, Djulbegovic B. Forero A. Gordon LI. Hernandez-Ilizaliturri FJ. Kaminski MS. Love G. Maloney DG. Mauch PM. Moore JO. Schilder RJ. Weiss L. Winter JN. Yahalom J. Zelenetz AD. Hodgkin disease/lymphoma. Clinical practice guidelines in oncology. Journal of the National Comprehensive Cancer Network.. 3: 210-230, 2006.
  • Prentice, AG.Glasmacher, A.Djulbegovic, B. In meta-analysis itraconazole is superior to fluconazole for prophylaxis of systemic fungal infection in the treatment of haematological malignancy. British journal of haematology. 132(5) : 656-8; author reply 658-9, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16445845
  • Bohlius, J.Wilson, J.Seidenfeld, J.Piper, M.Schwarzer, G.Sandercock, J.Trelle, S.Weingart, O.Bayliss, S.Djulbegovic, B.Bennett, CL.Langensiepen, S.Hyde, C.Engert, A. Recombinant human erythropoietins and cancer patients: updated meta-analysis of 57 studies including 9353 patients. Journal of the National Cancer Institute. 98(10) : 708-14, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16705125
  • Djulbegovic, B.Lyman, GH. Screening mammography at 40-49 years: regret or no regret? Lancet. 368(9552) : 2035-7, 2006. http://www.ncbi.nlm.nih.gov/pubmed/17161713
  • Djulbegovic, B.Frohlich, A.Bennett, CL. Acting on imperfect evidence: How much regret are we ready to accept? Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 23(28) : 6822-5, 2005. http://www.ncbi.nlm.nih.gov/pubmed/16145058
  • Vincent, S.Djulbegovic, B. Oncology treatment recommendations can be supported only by 1-2% of high-quality published evidence. Cancer treatment reviews. 31(4) : 319-22, 2005. http://www.ncbi.nlm.nih.gov/pubmed/16006047
  • Clark, OA.Lyman, GH.Castro, AA.Clark, LG.Djulbegovic, B. Colony-stimulating factors for chemotherapy-induced febrile neutropenia: a meta-analysis of randomized controlled trials. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 23(18) : 4198-214, 2005. http://www.ncbi.nlm.nih.gov/pubmed/15961767
  • Hozo, I.Djulbegovic, B.Clark, O.Lyman, GH. Use of re-randomized data in meta-analysis. BMC medical research methodology. 5: 17, 2005. http://www.ncbi.nlm.nih.gov/pubmed/15882470
  • Djulbegovic, B.Bickerdike, L. High-quality evidence in oncology from 1st September to 14th October 2004: a summary. Cancer treatment reviews. 31(2) : 155-7, 2005. http://www.ncbi.nlm.nih.gov/pubmed/15847985
  • Hozo, SP.Djulbegovic, B.Hozo, I. Estimating the mean and variance from the median, range, and the size of a sample. BMC medical research methodology. 5: 13, 2005. http://www.ncbi.nlm.nih.gov/pubmed/15840177
  • Soares, HP.Kumar, A.Daniels, S.Swann, S.Cantor, A.Hozo, I.Clark, M.Serdarevic, F.Gwede, C.Trotti, A.Djulbegovic, B. Evaluation of new treatments in radiation oncology: are they better than standard treatments? JAMA : the journal of the American Medical Association. 293(8) : 970-8, 2005. http://www.ncbi.nlm.nih.gov/pubmed/15728168
  • Djulbegovic, B.Bickerdike, L. High-quality evidence in oncology from 22nd June to 26th August 2004: a summary. Cancer treatment reviews. 31(1) : 63-7, 2005. http://www.ncbi.nlm.nih.gov/pubmed/15707707
  • Djulbegovic, B. Erythropoietin use in oncology: a summary of the evidence and practice guidelines comparing efforts of the Cochrane Review group and Blue Cross/Blue Shield to set up the ASCO/ASH guidelines. Best practice & research. Clinical haematology. 18(3) : 455-66, 2005. http://www.ncbi.nlm.nih.gov/pubmed/15792920
  • Stem cell Trialists Collaborative Group (PI: Djulbegovic B). Allogeneic Peripheral Blood Stem Cell Versus Bone Marrow Transplantation in the Management of Hematological Malignancies: An Individual Patient Data Meta-Analysis of 9 Randomized Trials and 1,111 Patients. J Clin Oncol. 23: 5074-5087, 2005.
  • Rodgers, GM.Cella, D.Chanan-Khan, A.Chesney, C.Cleeland, C.Coccia, PF.Demetri, GD.Djulbegovic, B.Garst, JL.Gore, M.Kraut, EH.Lin, WC.Millenson, M.Mock, V.Reinke, D.Rosenthal, J.Sabbatini, P. Cancer- and treatment-related anemia. Journal of the National Comprehensive Cancer Network : JNCCN. 3(6) : 772-89, 2005. http://www.ncbi.nlm.nih.gov/pubmed/16316613
  • Kumar, A.Soares, H.Wells, R.Clarke, M.Hozo, I.Bleyer, A.Reaman, G.Chalmers, I.Djulbegovic, B. Are experimental treatments for cancer in children superior to established treatments? Observational study of randomised controlled trials by the Children's Oncology Group. BMJ (Clinical research ed.). 331(7528) : 1295, 2005. http://www.ncbi.nlm.nih.gov/pubmed/16299015
  • Djulbegovic, B.Bickerdike, L. High-quality evidence in oncology from 19 May to 9 June 2005: a summary. Cancer treatment reviews. 31(8) : 653-6, 2005. http://www.ncbi.nlm.nih.gov/pubmed/16298072
  • Bickerdike, L.Djulbegovic, B. High-quality evidence in oncology from 14 April to 12 May 2005: a summary. Cancer treatment reviews. 31(7) : 587-9, 2005. http://www.ncbi.nlm.nih.gov/pubmed/16243438
  • Lyman, GH.Djulbegovic, B. The challenge of systematic reviews of diagnostic and staging studies in cancer. Cancer treatment reviews. 31(8) : 628-39, 2005. http://www.ncbi.nlm.nih.gov/pubmed/16225994
  • Mann H, Djulbegovic B. Biases due to differences in the treatments selected for comparison (comparator bias). James Lind Library. www.jameslindlibrary.org, 2004.
  • Djulbegovic B. Commentary on "Perceptions of equipoise are crucial to trial participation". Cochrane Collaboration Method Groups Newsletter. 8: 19-20, 2004.
  • Djulbegovic, B. Where is the evidence? European journal of cancer (Oxford, England : 1990). 40(18) : 2637, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15648121
  • Djulbegovic, B. Lifting the fog of uncertainty from the practice of medicine. BMJ (Clinical research ed.). 329(7480) : 1419-20, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15604164
  • Djulbegovic, B.Vincent, S. High-quality evidence in oncology from 18th May to 15th June 2004: a summary. Cancer treatment reviews. 30(8) : 721-3, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15541583
  • Djulbegovic, B.Vincent, S. High-quality evidence in oncology from 20th April to 11th May 2004: a summary. Cancer treatment reviews. 30(7) : 665-7, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15531400
  • Djulbegovic, B. Well informed uncertainties about the effects of treatment: paradox exists in dealing with uncertainty. BMJ (Clinical research ed.). 328(7446) : 1018, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15105342
  • Alsina, M.Fonseca, R.Wilson, EF.Belle, AN.Gerbino, E.Price-Troska, T.Overton, RM.Ahmann, G.Bruzek, LM.Adjei, AA.Kaufmann, SH.Wright, JJ.Sullivan, D.Djulbegovic, B.Cantor, AB.Greipp, PR.Dalton, WS.Sebti, SM. Farnesyltransferase inhibitor tipifarnib is well tolerated, induces stabilization of disease, and inhibits farnesylation and oncogenic/tumor survival pathways in patients with advanced multiple myeloma. Blood. 103(9) : 3271-7, 2004. http://www.ncbi.nlm.nih.gov/pubmed/14726402
  • Soares, HP.Daniels, S.Kumar, A.Clarke, M.Scott, C.Swann, S.Djulbegovic, B. Bad reporting does not mean bad methods for randomised trials: observational study of randomised controlled trials performed by the Radiation Therapy Oncology Group. BMJ (Clinical research ed.). 328(7430) : 22-4, 2004. http://www.ncbi.nlm.nih.gov/pubmed/14703540
  • Clark, OA.Lyman, G.Castro, AA.Clark, LG.Djulbegovic, B. Colony stimulating factors for chemotherapy induced febrile neutropenia. Cochrane database of systematic reviews (Online). (3) : CD003039, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12917942
  • Djulbegovic, B.Coleman, R.Stahel, R.Singh, D.Lyman, G. Evidence-based oncology in cancer treatment reviews. Cancer treatment reviews. 29(1) : 45-50, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12633579
  • Durie, BG.Kyle, RA.Belch, A.Bensinger, W.Blade, J.Boccadoro, M.Child, JA.Comenzo, R.Djulbegovic, B.Fantl, D.Gahrton, G.Harousseau, JL.Hungria, V.Joshua, D.Ludwig, H.Mehta, J.Morales, AR.Morgan, G.Nouel, A.Oken, M.Powles, R.Roodman, D.San Miguel, J.Shimizu, K.Singhal, S.Sirohi, B.Sonneveld, P.Tricot, G.Van Ness, B. Myeloma management guidelines: a consensus report from the Scientific Advisors of the International Myeloma Foundation. The hematology journal : the official journal of the European Haematology Association / EHA. 4(6) : 379-98, 2003. http://www.ncbi.nlm.nih.gov/pubmed/14671610
  • Glasmacher, A.Prentice, A.Gorschlüter, M.Engelhart, S.Hahn, C.Djulbegovic, B.Schmidt-Wolf, IG. Itraconazole prevents invasive fungal infections in neutropenic patients treated for hematologic malignancies: evidence from a meta-analysis of 3,597 patients. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 21(24) : 4615-26, 2003. http://www.ncbi.nlm.nih.gov/pubmed/14673051
  • Mann, H.Djulbegovic, B. Clinical equipoise and the therapeutic misconception. The Hastings Center report. 33(5) : 4; author reply 4-5, 2003. http://www.ncbi.nlm.nih.gov/pubmed/14696270
  • Djulbegovic, B.Cantor, A.Clarke, M. The importance of preservation of the ethical principle of equipoise in the design of clinical trials: relative impact of the methodological quality domains on the treatment effect in randomized controlled trials. Accountability in research. 10(4) : 301-15, 2003. http://www.ncbi.nlm.nih.gov/pubmed/14989285
  • Bepler, G.Goodridge Carney, D.Djulbegovic, B.Clark, RA.Tockman, M. A systematic review and lessons learned from early lung cancer detection trials using low-dose computed tomography of the chest. Cancer control : journal of the Moffitt Cancer Center. 10(4) : 306-14, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12915809
  • Lexchin, J.Bero, LA.Djulbegovic, B.Clark, O. Pharmaceutical industry sponsorship and research outcome and quality: systematic review. BMJ (Clinical research ed.). 326(7400) : 1167-70, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12775614
  • Mann, H.Djulbegovic, B.Gold, P. Failure of equipoise to resolve the ethical tension in a randomized clinical trial. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics. 31(1) : 5-6, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12762098
  • Kumar, A.Loughran, T.Alsina, M.Durie, BG.Djulbegovic, B. Management of multiple myeloma: a systematic review and critical appraisal of published studies. The lancet oncology. 4(5) : 293-304, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12732167
  • Mann, H.Djulbegovic, B. Choosing a control intervention for a randomised clinical trial. BMC medical research methodology. 3: 7, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12709266
  • Mann, H.Djulbegovic, B. Off-study availability of investigational treatments. Lancet. 361(9365) : 1302, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12699986
  • Strehl, J.Mey, U.Glasmacher, A.Djulbegovic, B.Mayr, C.Gorschlüter, M.Ziske, C.Schmidt-Wolf, IG. High-dose chemotherapy followed by autologous stem cell transplantation as first-line therapy in aggressive non-Hodgkin's lymphoma: a meta-analysis. Haematologica. 88(11) : 1304-15, 2003. http://www.ncbi.nlm.nih.gov/pubmed/14607760
  • Djulbegovic, B.Seidenfeld, J.Bonnell, C.Kumar, A. Nonmyeloablative allogeneic stem-cell transplantation for hematologic malignancies: a systematic review. Cancer control : journal of the Moffitt Cancer Center. 10(1) : 17-41, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12598853
  • He, Y.Wheatley, K.Clark, O.Glasmacher, A.Ross, H.Djulbegovic, B. Early versus deferred treatment for early stage multiple myeloma. Cochrane database of systematic reviews (Online). (1) : CD004023, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12535504
  • 96. The International Myeloma Working Group. Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group. Br J Haematol. 121: 749-757, 2003.
  • Djulbegovic, B.Singh, D. Evidence-based oncology section - aims and scope. Cancer treatment reviews. 29(1) : 51-3, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12633580
  • Djulbegovic B, Seidenfeld J, Bonnel C, Kumar A. Nonmyeloablative allogeneic stem cell transplantation for hematologic malignancies: a systematic review. Cancer Control. 10: 17-41, 2003.
  • Singh, D.Djulbegovic, B. Evidence-based Oncology section--policies and scope. Cancer treatment reviews. 29(2) : 121-2, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12670454
  • Bottomley, A.Thomas, R.Van Steen, K.Flechtner, H.Djulbegovic, B. Erythropoietin improves quality of life--a response. The lancet oncology. 3(9) : 527, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12217788
  • Clark O, Clark L, Cutler C, Wheatley K, Djulbegovic B. Allogeneic peripheral blood stem cells vs. bone marrow transplant for hematological malignancies (Protocol for the Cochrane Review). In: The Cochrane Library. (4) , 2002.
  • Djulbegovic, B.Wheatley, K.Ross, J.Clark, O.Bos, G.Goldschmidt, H.Cremer, F.Alsina, M.Glasmacher, A. Bisphosphonates in multiple myeloma. Cochrane database of systematic reviews (Online). (3) : CD003188, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12137679
  • Wheatley, K.Djulbegovic, B.Glasmacher, A. Priority-setting decisions for new cancer drugs. Lancet. 359(9316) : 1525, 2002. http://www.ncbi.nlm.nih.gov/pubmed/11988282
  • Lyman, GH.Kuderer, NM.Djulbegovic, B. Prophylactic granulocyte colony-stimulating factor in patients receiving dose-intensive cancer chemotherapy: a meta-analysis. The American journal of medicine. 112(5) : 406-11, 2002. http://www.ncbi.nlm.nih.gov/pubmed/11904116
  • Bottomley, A.Thomas, R.van Steen, K.Flechtner, H.Djulbegovic, B. Human recombinant erythropoietin and quality of life: a wonder drug or something to wonder about? The lancet oncology. 3(3) : 145-53, 2002. http://www.ncbi.nlm.nih.gov/pubmed/11902500
  • Cruse, H.Winiarek, M.Marshburn, J.Clark, O.Djulbegovic, B. Quality and methods of developing practice guidelines. BMC health services research. 2: 1, 2002. http://www.ncbi.nlm.nih.gov/pubmed/11825346
  • Kumar, A.Djulbegovic, B. Why evidence based oncology management. The Journal of oncology management : the official journal of the American College of Oncology Administrators. 11(6) : 13-6, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12502287
  • Rizzo, JD.Lichtin, AE.Woolf, SH.Seidenfeld, J.Bennett, CL.Cella, D.Djulbegovic, B.Goode, MJ.Jakubowski, AA.Lee, SJ.Miller, CB.Rarick, MU.Regan, DH.Browman, GP.Gordon, MS. Use of epoetin in patients with cancer: evidence-based clinical practice guidelines of the American Society of Clinical Oncology and the American Society of Hematology. Blood. 100(7) : 2303-20, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12239138
  • Clark, O.Adams, JR.Bennett, CL.Djulbegovic, B. Erythropoietin, uncertainty principle and cancer related anaemia. BMC cancer. 2: 23, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12270068
  • Djulbegovic B. Denominator problem needs to be addressed. BMJ. 325: 1420, 2002.
  • Djulbegovic, B. Association between competing interests and conclusions. Denominator problem needs to be addressed. BMJ (Clinical research ed.). 325(7377) : 1420; author reply 1420, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12480865
  • Adams JR, Lyman GH, Djubegovic B, Feinglass J, Bennett CL. G-CSF as prophylaxis of febrile neutropenia in SCLC. Expert Opin Pharmacother.. 3: 1273-81, 2002.
  • Rizzo, JD.Lichtin, AE.Woolf, SH.Seidenfeld, J.Bennett, CL.Cella, D.Djulbegovic, B.Goode, MJ.Jakubowski, AA.Lee, SJ.Miller, CB.Rarick, MU.Regan, DH.Browman, GP.Gordon, MS. Use of epoetin in patients with cancer: evidence-based clinical practice guidelines of the American Society of Clinical Oncology and the American Society of Hematology. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 20(19) : 4083-107, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12351606
  • Djulbegovic, B.Hozo, I. At what degree of belief in a research hypothesis is a trial in humans justified? Journal of evaluation in clinical practice. 8(2) : 269-76, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12180373
  • Lilford, RJ.Djulbegovic, B. Declaration of Helsinki should be strengthened. Equipoise is essential principle of human experimentation. BMJ (Clinical research ed.). 322(7281) : 299-300, 2001. http://www.ncbi.nlm.nih.gov/pubmed/11157551
  • Djulbegovic, B.Clarke, M. Scientific and ethical issues in equivalence trials. JAMA : the journal of the American Medical Association. 285(9) : 1206-8, 2001. http://www.ncbi.nlm.nih.gov/pubmed/11231752
  • Lilford, RJ.Djulbegovic, B. Uncertainty about clinical equipoise. Equipose and uncertainty principle are not mutually exclusive. BMJ (Clinical research ed.). 322(7289) : 795, 2001. http://www.ncbi.nlm.nih.gov/pubmed/11322146
  • Djulbegovic, B. Placebo-controlled trials. Annals of internal medicine. 135(1) : 62-4, 2001. http://www.ncbi.nlm.nih.gov/pubmed/11434740
  • Djulbegovic, B.Clarke, M. Ethical issues in the reporting of clinical trials. JAMA : the journal of the American Medical Association. 286(13) : 1577-8, 2001. http://www.ncbi.nlm.nih.gov/pubmed/11585477
  • Djulbegovic, B.Cohen, Y. The natural history of refractory idiopathic thrombocytopenic purpura. Blood. 98(7) : 2282-3, 2001. http://www.ncbi.nlm.nih.gov/pubmed/11592263
  • Djulbegovic, B.Wheatley, K.Ross, J.Clark, O.Bos, G.Goldschmidt, H.Cremer, F.Alsina, M.Glasmacher, A. Bisphosphonates in multiple myeloma. Cochrane database of systematic reviews (Online). (4) : CD003188, 2001. http://www.ncbi.nlm.nih.gov/pubmed/11687178
  • Clark, O.Clark, L.Djulbegovic, B. Is clinical research still too haphazard? Lancet. 358(9293) : 1648, 2001. http://www.ncbi.nlm.nih.gov/pubmed/11716926
  • Djulbegovic, B.Adams, JR.Lyman, GH.Lacevic, M.Hozo, I.Greenwich, M.Bennett, CL. Evaluation and appraisal of randomized controlled trials in myeloma. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 12(11) : 1611-7, 2001. http://www.ncbi.nlm.nih.gov/pubmed/11822763
  • Kantardzic M, Hamdan H, Djulbegovic B. Artificial Neural Networks Approach in Diagnostics of Polycythemia Vera. Internat J Computers and Their Applications.. 8: 74-79, 2001.
  • Djulbegovic B. Commentary to the CONSORT Statement: revised recommendations for improving the quality of reports of parallel group randomized trials. Cochrane Collaboration Methods Groups Newsletter. 5: 11-12, 2001.
  • Djulbegovic B, Clarke M. Informing patients about uncertainty in clinical trials. JAMA. 285: 2713-2714, 2001.
  • Lyman GH, Djulbegovic B. Understanding economic analyses. Evidence-based Oncology. 2: 2-5, 2001.
  • Djulbegovic B. Placebo-controlled trials. Ann Intern Med. 135: 62-63, 2001.
  • Djulbegovic B. Commentary on "Clinical score for cancer patients with febrile neutropenia. ACP J Club. 134: 76, 2001.
  • Djulbegovic, B. Acknowledgment of uncertainty: a fundamental means to ensure scientific and ethical validity in clinical research. Current oncology reports. 3(5) : 389-95, 2001. http://www.ncbi.nlm.nih.gov/pubmed/11489238
  • Djulbegovic, B.Hozo, I.Lyman, GH. Linking evidence-based medicine therapeutic summary measures to clinical decision analysis. MedGenMed : Medscape general medicine. 2(1) : E6, 2000. http://www.ncbi.nlm.nih.gov/pubmed/11104452
  • Cohen, YC.Djulbegovic, B.Shamai-Lubovitz, O.Mozes, B. The bleeding risk and natural history of idiopathic thrombocytopenic purpura in patients with persistent low platelet counts. Archives of internal medicine. 160(11) : 1630-8, 2000. http://www.ncbi.nlm.nih.gov/pubmed/10847256
  • Djulbegovic, B. Acquired anaemias and polycythaemia. Lancet. 356(9229) : 596, 2000. http://www.ncbi.nlm.nih.gov/pubmed/10950261
  • Djulbegovic, B.Lacevic, M.Cantor, A.Fields, KK.Bennett, CL.Adams, JR.Kuderer, NM.Lyman, GH. The uncertainty principle and industry-sponsored research. Lancet. 356(9230) : 635-8, 2000. http://www.ncbi.nlm.nih.gov/pubmed/10968436
  • Djulbegovic, B.Morris, L.Lyman, GH. Evidentiary challenges to evidence-based medicine. Journal of evaluation in clinical practice. 6(2) : 99-109, 2000. http://www.ncbi.nlm.nih.gov/pubmed/10970004
  • Knox, KS.Adams, JR.Djulbegovic, B.Stinson, TJ.Tomor, C.Bennet, CL. Reporting and dissemination of industry versus non-profit sponsored economic analyses of six novel drugs used in oncology. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 11(12) : 1591-5, 2000. http://www.ncbi.nlm.nih.gov/pubmed/11205468
  • Djulbegovic, B.Lyman, GH.Hozo, I. Talking about treatment. Annals of internal medicine. 132(1) : 94, 2000. http://www.ncbi.nlm.nih.gov/pubmed/10627263
  • Knox KS, Adams JR, Djulbegovic B, Stinson TJ, Bennett CL. Quality and Dissemination of Industry Sponsored Economic Analyses of Six Novel Drugs Used in Oncology. Ann Oncology. 11: 1591-1595, 2000.
  • Djulbegovic B, Cantor A, Lyman GH, Ruckdeschel JC. Understanding treatment benefits and harms. Evidence-based Oncology. 1: 66-68, 2000.
  • Lilford RJ, Djulbegovic B. Equipoise is essential principle of human experimentation. BMJ. 322: 299-300, 2000.
  • Djulbegovic B. Thalidomide is active drug against myeloma that failed transplant. In: Evidence-based Oncology. 1: 16-17, 2000.
  • Djulbegovic B, Lyman GH, Ruckdeschel J. Why Evidence-based Oncology. Evidence-based Oncology. , 2000.
  • Djulbegovic B, Bennett CL, Adams JR, Lyman GH. Industry-sponsored research. Lancet. 356: 2194, 2000.
  • Djulbegovic, B.Hozo, I. Computer program for the diagnosis and treatment of polycythemia rubra vera. M.D. computing : computers in medical practice. 16(1) : 83-9, 1999. http://www.ncbi.nlm.nih.gov/pubmed/10202430
  • Djulbegovic, B.Loughran, TP.Hornung, CA.Kloecker, G.Efthimiadis, EN.Hadley, TJ.Englert, J.Hoskins, M.Goldsmith, GH. The quality of medical evidence in hematology-oncology. The American journal of medicine. 106(2) : 198-205, 1999. http://www.ncbi.nlm.nih.gov/pubmed/10230750
  • Hozo, I.Djulbegovic, B. Using the Internet to calculate clinical action thresholds. Computers and biomedical research, an international journal. 32(2) : 168-85, 1999. http://www.ncbi.nlm.nih.gov/pubmed/10337498
  • Djulbegovic, B.Hozo, I.Schwartz, A.McMasters, KM. Acceptable regret in medical decision making. Medical hypotheses. 53(3) : 253-9, 1999. http://www.ncbi.nlm.nih.gov/pubmed/10580533
  • Djulbegovic, B.Hendler, FJ.Pavletic, S. Reasoning by Identifying Goals of Treatment. Cancer control : journal of the Moffitt Cancer Center. 6(4) : 377-384, 1999. http://www.ncbi.nlm.nih.gov/pubmed/10758570
  • Djulbegovic B. Two systematic reviews-two different answers. BMJ. , 1999.
  • Hozo, I.Djulbegovic, B. Calculating confidence intervals for threshold and post-test probabilities. M.D. computing : computers in medical practice. 15(2) : 110-5, 1998. http://www.ncbi.nlm.nih.gov/pubmed/9540324
  • Djulbegovic, B.Hozo, I.Fields, KK.Sullivan, D. High-Dose Chemotherapy in the Adjuvant Treatment of Breast Cancer: Benefit/Risk Analysis. Cancer control : journal of the Moffitt Cancer Center. 5(5) : 394-405, 1998. http://www.ncbi.nlm.nih.gov/pubmed/10761089
  • Djulbegovic B and Hozo I. Acting on evidence can only be done within the context of decision analysis. BMJ. , 1998.
  • Djulbegovic B The Chief Knowledge Officer vs. Improvement in Science of Information Dissemination? BMJ. , 1998.
  • Djulbegovic, B.Hadley, T. Evaluating the quality of clinical guidelines. Linking decisions to medical evidence. Oncology (Williston Park, N.Y.). 12(11A) : 310-4, 1998. http://www.ncbi.nlm.nih.gov/pubmed/10028514
  • Djulbegovic B, Goldsmith G, Vaughn D, Birkimer J, Marasa M, Joseph G, Huang A, and Hadley T. Comparison of the quality of life between HIV positive hemophilia patients and HIV negative hemophilia patients. Haemophilia. 2: 166-172, 1996.
  • Djulbegovic, B.Desoky, AH. Equation and nomogram for calculation of testing and treatment thresholds. Medical decision making : an international journal of the Society for Medical Decision Making. 16(2) : 198-9, 1996. http://www.ncbi.nlm.nih.gov/pubmed/8778540
  • Djulbegovic, B.Marasa, M.Pesto, A.Kushner, GM.Hadley, T.Joseph, G.Goldsmith, G. Safety and efficacy of purified factor IX concentrate and antifibrinolytic agents for dental extractions in hemophilia B. American journal of hematology. 51(2) : 168-70, 1996. http://www.ncbi.nlm.nih.gov/pubmed/8579061
  • Djulbegovic, B.Hannan, MM.Bergman, GE. Concomitant treatment with factor IX concentrates and antifibrinolytics in hemophilia B. Acta haematologica. 94 Suppl 1: 43-7; discussion 48, 1995. http://www.ncbi.nlm.nih.gov/pubmed/7571994
  • Djulbegovic, B. Lack of prophylactic anticoagulant therapy is not associated with clinical thrombotic complications in patients with hemophilia who undergo orthopedic surgical procedures. American journal of hematology. 50(3) : 229-30, 1995. http://www.ncbi.nlm.nih.gov/pubmed/7485094
  • Djulbegovic, B. Clinical problem-solving: still hazy after all these years. The New England journal of medicine. 332(5) : 333, 1995. http://www.ncbi.nlm.nih.gov/pubmed/7816074
  • Djulbegovic, B.Hozo, I.Abdomerovic, I.Hozo, S. Diagnostic entropy as a function of therapeutic benefit/risk ratio. Medical hypotheses. 45(5) : 503-9, 1995. http://www.ncbi.nlm.nih.gov/pubmed/8748096
  • Djulbegovic, B.Goldsmith, GH. Guidelines for management of hemophilia A and B. Blood. 85(2) : 598-9, 1995. http://www.ncbi.nlm.nih.gov/pubmed/7812015
  • Joseph, G.Smith, KJ.Hadley, TJ.Djulbegovic, B.Troup, GM.Oldfather, J.Barker, RL. HLA-DR53 protects against thrombotic thrombocytopenic purpura/adult hemolytic uremic syndrome. American journal of hematology. 47(3) : 189-93, 1994. http://www.ncbi.nlm.nih.gov/pubmed/7942782
  • Joseph, G.Hadley, T.Djulbegovic, B.Hamm, J.Seeger, J.Blumenreich, M.Woodcock, T. High-dose chlorambucil and dexamethasone for relapsed non-Hodgkin's lymphomas. American journal of clinical oncology. 16(4) : 319-22, 1993. http://www.ncbi.nlm.nih.gov/pubmed/8328409
  • Djulbegovic, B. An estimation of life expectancy: the method is a message. Medical decision making : an international journal of the Society for Medical Decision Making. 13(3) : 245-6, 1993. http://www.ncbi.nlm.nih.gov/pubmed/8412554
  • Djulbegovic, B.Woodcock, TM. Mathematical modeling or waiting decades for an empirical answer? Medical decision making : an international journal of the Society for Medical Decision Making. 12(1) : 77, 1992. http://www.ncbi.nlm.nih.gov/pubmed/1538636
  • Djulbegovic, B.Hendler, FJ.Hamm, J.Hadley, T.Woodcock, TM. Residual mediastinal mass after treatment of Hodgkin's disease: a decision analysis. Medical hypotheses. 38(2) : 166-75, 1992. http://www.ncbi.nlm.nih.gov/pubmed/1528159
  • Djulbegovic, B.Blumenreich, M.Hadley, T.Joseph, G. Meta-analysis of chemotherapy in multiple myeloma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 10(8) : 1366-7, 1992. http://www.ncbi.nlm.nih.gov/pubmed/1386103
  • Hadley, T.Djulbegovic, B. Disseminated intravascular coagulation after factor IX complex resolved using purified factor IX concentrate. Annals of internal medicine. 115(8) : 621-2, 1991. http://www.ncbi.nlm.nih.gov/pubmed/1892334
  • Djulbegovic, B.Hadley, T.Joseph, G. A new algorithm for the diagnosis of polycythemia. American family physician. 44(1) : 113-20, 1991. http://www.ncbi.nlm.nih.gov/pubmed/2058526
  • Djulbegović, B.Hadley, T.Yen, F. Occurrence of high-grade T-cell lymphoma in a patient with Philadelphia chromosome-negative chronic myelogenous leukemia with breakpoint cluster region rearrangement: case report and review of the literature. American journal of hematology. 36(1) : 63-4, 1991. http://www.ncbi.nlm.nih.gov/pubmed/1984685
  • Djulbegovic, B.Hollenberg, J.Woodcock, TM.Herzig, R. Comparison of different treatment strategies for diffuse large-cell lymphomas: a decision analysis. Medical decision making : an international journal of the Society for Medical Decision Making. 11(1) : 1-8, 1991. http://www.ncbi.nlm.nih.gov/pubmed/1709713
  • Pasic R, Djulbegovic B, Softic Dz, Wittliff JL. Steroid receptors and breast cancer. Med Pregl. 1-2: 48-51, 1991.
  • Pasic, R.Djulbegovic, B.Wittliff, JL. Comparison of sex steroid receptor determinations in human breast cancer by enzyme immunoassay and radioligand binding. Journal of clinical laboratory analysis. 4(6) : 430-6, 1990. http://www.ncbi.nlm.nih.gov/pubmed/2283562
  • Djulbegoviĉ, B.Hadley, T.Paŝiĉ, R. A new algorithm for diagnosis of anemia. Postgraduate medicine. 85(5) : 119-22, 127-30, 1989. http://www.ncbi.nlm.nih.gov/pubmed/2648368
  • Pasic, R.Djulbegovic, B.Wittliff, JL. Influence of O.C.T. embedding compound on determinations of estrogen and progestin receptors in breast cancer. Clinical chemistry. 35(12) : 2317-9, 1989. http://www.ncbi.nlm.nih.gov/pubmed/2591050
  • Denic S, Djulbegovic B, Ridzanovic Z. Optimal timing of bone marrow transplantation in chronic myelogenous leukemia. Period Biol. 91: 391-396, 1989.
  • Ridzanovic Z, Djulbegovic B. Reasons and practice of poor diagnostic testing. Lijec Vjesn. 110: 395-401, 1988.
  • Scepanovic D, Djulbegovic B. Some genetic considerations on Buerger's disease. In: Proceedings of I Yugoslav Congress of Angiology.. : 381-392, 1988.
  • Djulbegović, B.Christmas, SE.Moore, M. Differentiated HL-60 promyelocytic leukaemia cells produce a factor inducing differentiation. Leukemia research. 11(3) : 259-64, 1987. http://www.ncbi.nlm.nih.gov/pubmed/3470575
  • Djulbegovic B, Secerbegovic S. Diagnosis of acute ischaemic heart disease with an aid of a personal computer. Lijec Vjesn. 108: 380-383, 1986.
  • Djulbegović, B.Christmas, SE.Evans, G.Moore, M. Studies of the effect of 1,25-dihydroxycholecalciferol on the proliferation and differentiation of the human promyelocytic leukaemia cell line HL-60. Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie. 40(10) : 407-16, 1986. http://www.ncbi.nlm.nih.gov/pubmed/3472610
  • Djulbegović, B.Svetina, S. Mathematical model of acute myeloblastic leukaemia: an investigation of the relevant kinetic parameters. Cell and tissue kinetics. 18(3) : 307-19, 1985. http://www.ncbi.nlm.nih.gov/pubmed/3857125
  • Kusec Lj, Djulbegovic B, Obradov S et al. Prognostic factors in multiple myeloma. Med Arh. 38: 203-211, 1984.
  • Djulbegovic B, Konjicija A. Mathematical basis of clinical judgement. Med Arh. 38: 245-258, 1984.
  • Serdarevic Dz, Djulbegovic B, Mulabegovic N. Drug effects on laboratory tests. Med Arh. 33: 379-385, 1979.
  • Djulbegovic B, Filipovic S. Studies of lactate dehydrogenase isoenzymes in human tissues. Med pod. 28: 47-52, 1976.
  • Djulbegovic B. Analysis of lactate dehydrogenase isoenzymes in fundus and pyloric stomach mucosa in healthy people and patients suffering from chronic gastritis. Glas Medic. 16: 177-185, 1976.
  • Djulbegovic B, Filipovic S. Electrophoretic analysis of lactate isoenzymes in human tissues. Glas Medic. 15: 12-18, 1975.

Positions Held

  • co-Director (USF Clinical Translational Science Institute, University of South Florida 2008 - 2013)
  • Medical Director (Cancer Registry, H. Lee Moffitt Cancer Center & Research Institute 2005 - 2008)
  • Director (Section on Evidence-based Medicine and Decision Sciences, H. Lee Moffitt Cancer Center & Research Institute 2007 - 2008)
  • Director (Clinical Research, Hematology-Oncology Program, H. Lee Moffitt Cancer Center & Research Institute, University of South Florida 2003 - 2005)
  • Associate Professor (with tenure) (Medicine and Oncology, University of South Florida 1998 - 2003)
  • Director (Fellowship Program in Division of Blood and Bone Marrow Transplant, H. Lee Moffitt Cancer Center & Research Institute, University of South Florida 1999 - 2001)
  • Director (Hemophilia Program, Kentucky Program for Handicapped Children 1994 - 1998)
  • Associate Professor (with tenure) (College of Medicine, University of Louisville 1996 - 1998)
  • Assistant Professor (College of Medicine, University of Louisville 1990 - 1996)

Awards/Honors

  • Editorial Board of the 2013 IMIA selection: BMC Med Inform Decis Mak 2012;12(94):239-47 (The International Medical Informatics Association: Yearbook of Medical Informatics - 2013)
  • BMJ's Minerva's lead story: Nature 2013;500:395-396 (BMJ - 2013)
  • Faculty Outstanding Research Achievement Award (University of South Florida - 2013)
  • New treatments compared to established treatments in randomized trials (Published in The Cochrane Library - 2012)
  • Selected in 1% of top US doctors (US News & World Report - 2012)
  • The Thomas C. Chalmers Award (senior author) (19th Annual Cochrane Colloquium, Madrid - 2011)
  • Selected in 1% of top US doctors (US News & World Report - 2011)
  • Publication Award to the scientist with publication with highest average impact factor (H. Lee Moffitt Cancer Center & Research Institute - 2007)
  • Elected as Fellow (Fellow of the American College of Physicians (FACP) - 2005)
  • The Thomas C. Chalmers Award (VII Cochrane Colloquium: The Best Evidence for Health Care - 1999)
  • First place for the poster "Regret in Clinical Decision Making" (Second Annual Medical Research Competition Research!Louisville - 1997)
  • Best Books in 1993 (for the book by Djulbegovic B. : Reasoning and Decision making in Hematology) (Journal National Cancer Institute - 1994)