Evidence-Based Medicine

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Ambuj Kumar, MD MPH

Assistant Professor, College Of Medicine Internal Medicine

Assoc Professor, College Of Medicine Internal Medicine

College Of Medicine Internal Medicine

Contact Info Division of Evidence Based Medicine
3515 East Fletcher Avenue, MDC 27
Tampa, FL 33612

Academic Email: akumar1@health.usf.edu

Academic Phone: (813) 396-9194

View My C.V.

Education

  • MPH, Maternal & Child Health, University Of South Florida, 2001
  • MD, Medicine, Tver State Medical Institute, 1998

Recent Publications

  • Djulbegovic, B.Elqayam, S.Reljic, T.Hozo, I.Miladinovic, B.Tsalatsanis, A.Kumar, A.Beckstead, J.Taylor, S.Cannon-Bowers, J. How do physicians decide to treat: an empirical evaluation of the threshold model. BMC medical informatics and decision making. 14(1) : 47, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24903517
  • Abu-Dalle, I.Reljic, T.Nishihori, T.Antar, A.Bazarbachi, A.Djulbegovic, B.Kumar, A.Kharfan-Dabaja, MA. Extracorporeal photopheresis in steroid-refractory acute or chronic graft-versus-host disease: results of a systematic review of prospective studies. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. , 2014. http://www.ncbi.nlm.nih.gov/pubmed/24867779
  • Muhammad, A.Lamendola, O.Daas, A.Kumar, A.Vidyarthi, G. Association between colonic diverticulosis and prevalence of colorectal polyps. International journal of colorectal disease. , 2014. http://www.ncbi.nlm.nih.gov/pubmed/24866344
  • Reljic, T.Mahony, H.Djulbegovic, B.Etchason, J.Paxton, H.Flores, M.Kumar, A. Value of repeat head computed tomography after traumatic brain injury: systematic review and meta-analysis. Journal of neurotrauma. 31(1) : 78-98, 2014. http://www.ncbi.nlm.nih.gov/pubmed/23914924
  • Koskan, A.Klasko, L.Davis, SN.Gwede, CK.Wells, KJ.Kumar, A.Lopez, N.Meade, CD. Use and Taxonomy of Social Media in Cancer-Related Research: A Systematic Review. American journal of public health. 104(7) : e20-e37, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24832403
  • Djulbegovic, B.Beckstead, JW.Elqayam, S.Reljic, T.Hozo, I.Kumar, A.Cannon-Bowers, J.Taylor, S.Tsalatsanis, A.Turner, B.Paidas, C. Evaluation of Physicians' Cognitive Styles. Medical decision making : an international journal of the Society for Medical Decision Making. , 2014. http://www.ncbi.nlm.nih.gov/pubmed/24722474
  • Mhaskar, RS.Reljic, T.Wao, H.Kumar, A.Miladinovic, B.Djulbegovic, B. Treatment-related harms: what was planned and what was reported? National Cancer Institute's Co-operative group phase III randomized controlled trials: a systematic review. Journal of clinical epidemiology. 67(3) : 354-6, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24055164
  • Wao, H.Mhaskar, R.Kumar, A.Miladinovic, B.Djulbegovic, B. Survival of patients with non-small cell lung cancer without treatment: a systematic review and meta-analysis. Systematic reviews. 2: 10, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23379753
  • Kharfan-Dabaja, MA.Hamadani, M.Reljic, T.Nishihori, T.Bensinger, W.Djulbegovic, B.Kumar, A. Comparative efficacy of tandem autologous versus autologous followed by allogeneic hematopoietic cell transplantation in patients with newly diagnosed multiple myeloma: a systematic review and meta-analysis of randomized controlled trials. Journal of hematology & oncology. 6: 2, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23289975
  • Miladinovic, B.Mhaskar, R.Hozo, I.Kumar, A.Mahony, H.Djulbegovic, B. Optimal information size in trial sequential analysis of time-to-event outcomes reveals potentially inconclusive results because of the risk of random error. Journal of clinical epidemiology. 66(6) : 654-9, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23403248
  • Djulbegovic, B.Kumar, A.Miladinovic, B.Reljic, T.Galeb, S.Mhaskar, A.Mhaskar, R.Hozo, I.Tu, D.Stanton, HA.Booth, CM.Meyer, RM. Treatment success in cancer: industry compared to publicly sponsored randomized controlled trials. PloS one. 8(3) : e58711, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23555593
  • Mhaskar, R.Alandikar, V.Emmanuel, P.Djulbegovic, B.Patel, S.Patel, A.Naik, E.Mohapatra, S.Kumar, A. Adherence to antiretroviral therapy in India: a systematic review and meta-analysis. Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine. 38(2) : 74-82, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23878418
  • Muhammad, A.Dhamija, M.Vidyarthi, G.Amodeo, D.Boyd, W.Miladinovic, B.Kumar, A. Comparative effectiveness of traditional chemoembolization with or without sorafenib for hepatocellular carcinoma. World journal of hepatology. 5(7) : 364-71, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23898369
  • Djulbegovic, B.Kumar, A.Glasziou, P.Miladinovic, B.Chalmers, I. Medical research: Trial unpredictability yields predictable therapy gains. Nature. 500(7463) : 395-6, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23969443
  • Duong, VH.Lin, K.Reljic, T.Kumar, A.Al Ali, NH.Lancet, JE.List, AF.Komrokji, RS. Poor outcome of patients with myelodysplastic syndrome after azacitidine treatment failure. Clinical lymphoma, myeloma & leukemia. 13(6) : 711-5, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24054159
  • Kharfan-Dabaja, MA.Hamadani, M.Reljic, T.Pyngolil, R.Komrokji, RS.Lancet, JE.Fernandez, HF.Djulbegovic, B.Kumar, A. Gemtuzumab ozogamicin for treatment of newly diagnosed acute myeloid leukaemia: a systematic review and meta-analysis. British journal of haematology. 163(3) : 315-25, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24033280
  • Miladinovic, B.Kumar, A.Hozo, I.Mahony, H.Djulbegovic, B. Trial sequential analysis may be insufficient to draw firm conclusions regarding statistically significant treatment differences using observed intervention effects: a case study of meta-analyses of multiple myeloma trials. Contemporary clinical trials. 34(2) : 257-61, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23274403
  • Miladinovic, B.Mhaskar, R.Kumar, A.Kim, S.Schonwetter, R.Djulbegovic, B. External validation of a web-based prognostic tool for predicting survival for patients in hospice care. Journal of palliative care. 29(3) : 140-6, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24380212
  • Djulbegovic, B.Kumar, A.Glasziou, PP.Perera, R.Reljic, T.Dent, L.Raftery, J.Johansen, M.Di Tanna, GL.Miladinovic, B.Soares, HP.Vist, GE.Chalmers, I. New treatments compared to established treatments in randomized trials. The Cochrane database of systematic reviews. 10: MR000024, 2012. http://www.ncbi.nlm.nih.gov/pubmed/23076962
  • Miladinovic, B.Kumar, A.Mhaskar, R.Kim, S.Schonwetter, R.Djulbegovic, B. A flexible alternative to the Cox proportional hazards model for assessing the prognostic accuracy of hospice patient survival. PloS one. 7(10) : e47804, 2012. http://www.ncbi.nlm.nih.gov/pubmed/23082220
  • Quinn, GP.Pal, T.Murphy, D.Vadaparampil, ST.Kumar, A. High-risk consumers' perceptions of preimplantation genetic diagnosis for hereditary cancers: a systematic review and meta-analysis. Genetics in medicine : official journal of the American College of Medical Genetics. 14(2) : 191-200, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22261755
  • Kumar, A.Mhaskar, AR.Reljic, T.Mhaskar, RS.Kharfan-Dabaja, MA.Anasetti, C.Mohty, M.Djulbegovic, B. Antithymocyte globulin for acute-graft-versus-host-disease prophylaxis in patients undergoing allogeneic hematopoietic cell transplantation: a systematic review. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 26(4) : 582-8, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22182922
  • Mhaskar, R.Djulbegovic, B.Magazin, A.Soares, HP.Kumar, A. Published methodological quality of randomized controlled trials does not reflect the actual quality assessed in protocols. Journal of clinical epidemiology. 65(6) : 602-9, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22424985
  • Aslam, S.Georgiev, H.Mehta, K.Kumar, A. Matching research design to clinical research questions. Indian journal of sexually transmitted diseases. 33(1) : 49-53, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22529457
  • Mhaskar, R.Redzepovic, J.Wheatley, K.Clark, OA.Miladinovic, B.Glasmacher, A.Kumar, A.Djulbegovic, B. Bisphosphonates in multiple myeloma: a network meta-analysis. The Cochrane database of systematic reviews. 5: CD003188, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22592688
  • Wells, KJ.Luque, JS.Miladinovic, B.Vargas, N.Asvat, Y.Roetzheim, RG.Kumar, A. Do community health worker interventions improve rates of screening mammography in the United States? A systematic review. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 20(8) : 1580-98, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21653645
  • Kumar, A.Hozo, I.Wheatley, K.Djulbegovic, B. Thalidomide versus bortezomib based regimens as first-line therapy for patients with multiple myeloma: a systematic review. American journal of hematology. 86(1) : 18-24, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21120867
  • Lu, B.Kumar, A.Castellsague, X.Giuliano, AR. Efficacy and Safety of Prophylactic Vaccines against Cervical HPV Infection and Diseases among Women: A Systematic Review & Meta-Analysis. BMC infectious diseases. 11(1) : 13, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21226933
  • Pidala, J.Djulbegovic, B.Anasetti, C.Kharfan-Dabaja, M.Kumar, A. Allogeneic hematopoietic cell transplantation for adult acute lymphoblastic leukemia (ALL) in first complete remission. Cochrane database of systematic reviews (Online). (10) : CD008818, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21975786
  • Miladinovic, B.Kumar, A.Hozo, I.Djulbegovic, B. Instrumental variable meta-analysis of individual patient data: application to adjust for treatment non-compliance. BMC medical research methodology. 11: 55, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21510899
  • Kumar, A.Galeb, S.Djulbegovic, B. Treatment of patients with multiple myeloma: an overview of systematic reviews. Acta haematologica. 125(1-2) : 8-22, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21150183
  • Quinn, GP.Pal, T.Murphy, D.Vadaparampil, ST.Kumar, A. High-risk consumers' perceptions of preimplantation genetic diagnosis for hereditary cancers: A systematic review and meta-analysis. Genetics in medicine : official journal of the American College of Medical Genetics. , 2011. http://www.ncbi.nlm.nih.gov/pubmed/21918462
  • Djulbegovic, B.Kumar, A.Magazin, A.Schroen, AT.Soares, H.Hozo, I.Clarke, M.Sargent, D.Schell, MJ. Optimism bias leads to inconclusive results-an empirical study. Journal of clinical epidemiology. , 2010. http://www.ncbi.nlm.nih.gov/pubmed/21163620
  • Mhaskar, R.Redzepovic, J.Wheatley, K.Clark, OA.Miladinovic, B.Glasmacher, A.Kumar, A.Djulbegovic, B. Bisphosphonates in multiple myeloma. Cochrane database of systematic reviews (Online). (3) : CD003188, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20238320
  • Kumar, A.List, AF.Hozo, I.Komrokji, R.Djulbegovic, B. Decitabine versus 5-azacitidine for the treatment of myelodysplastic syndrome: adjusted indirect meta-analysis. Haematologica. 95(2) : 340-2; author reply 343-4, 2010. http://www.ncbi.nlm.nih.gov/pubmed/19850902
  • Kharfan-Dabaja, MA.Mhaskar, AR.Djulbegovic, B.Cutler, C.Mohty, M.Kumar, A. Efficacy of rituximab in the setting of steroid-refractory chronic graft-versus-host disease: a systematic review and meta-analysis. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 15(9) : 1005-13, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19660713
  • Kumar, A.Kharfan-Dabaja, MA.Glasmacher, A.Djulbegovic, B. Tandem versus single autologous hematopoietic cell transplantation for the treatment of multiple myeloma: a systematic review and meta-analysis. Journal of the National Cancer Institute. 101(2) : 100-6, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19141779
  • Mhaskar, R.Kumar, A.Behera, M.Kharfan-Dabaja, MA.Djulbegovic, B. Role of high-dose chemotherapy and autologous hematopoietic cell transplantation in primary systemic amyloidosis: a systematic review. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 15(8) : 893-902, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19589478
  • Djulbegovic, B.Kumar, A. Multiple myeloma: detecting the effects of new treatments. Lancet. 371(9625) : 1642-4, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18486726
  • Pal, T.Permuth-Wey, J.Kumar, A.Sellers, TA. Systematic review and meta-analysis of ovarian cancers: estimation of microsatellite-high frequency and characterization of mismatch repair deficient tumor histology. Clinical cancer research : an official journal of the American Association for Cancer Research. 14(21) : 6847-54, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18980979
  • Djulbegovic, B.Kumar, A.Soares, HP.Hozo, I.Bepler, G.Clarke, M.Bennett, CL. Treatment success in cancer: new cancer treatment successes identified in phase 3 randomized controlled trials conducted by the National Cancer Institute-sponsored cooperative oncology groups, 1955 to 2006. Archives of internal medicine. 168(6) : 632-42, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18362256
  • Behera, M.Kumar, A.Soares, HP.Sokol, L.Djulbegovic, B. Evidence-based medicine for rare diseases: implications for data interpretation and clinical trial design. Cancer control : journal of the Moffitt Cancer Center. 14(2) : 160-6, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17387301
  • Kumar, A.Soares, HP.Balducci, L.Djulbegovic, B. Treatment tolerance and efficacy in geriatric oncology: a systematic review of phase III randomized trials conducted by five National Cancer Institute-sponsored cooperative groups. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 25(10) : 1272-6, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17401017
  • Kharfan-Dabaja, MA.Kumar, A.Behera, M.Djulbegovic, B. Systematic review of high dose chemotherapy and autologous haematopoietic stem cell transplantation for chronic lymphocytic leukaemia: what is the published evidence? British journal of haematology. 139(2) : 234-42, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17897299
  • Soares, HP.Kumar, A.Djulbegovic, B. Evidence profiles for breast cancer: benefit/harms data based on the totality of randomized evidence. Cancer treatment reviews. 33(1) : 87-9, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17081695
  • Soares, HP.Kumar, A.Djulbegovic, B. Evidence profiles for lung cancer: benefit/harms data based on the totality of randomized evidence. Cancer treatment reviews. 32(8) : 652-5, 2006. http://www.ncbi.nlm.nih.gov/pubmed/17008011
  • Kumar, A.Djulbegovic, B. Myeloma (multiple). Clinical evidence. (15) : 1-29, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16973003
  • Kumar, A.Soares, HP.Djulbegovic, B. Evidence profiles for colo-rectal cancer: benefit/harms data based on the totality of randomized evidence. Cancer treatment reviews. 32(7) : 577-80, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16919883
  • Djulbegovic, B.Soares, HP.Kumar, A. What kind of evidence do patients and practitioners need: evidence profiles based on 5 key evidence-based principles to summarize data on benefits and harms. Cancer treatment reviews. 32(7) : 572-6, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16914268
  • Kumar, A.Soares, HP. Salvage radiotherapy increases survival in people with residual disease after chemotherapy for advance diffuse large cell lymphoma. Cancer treatment reviews. 32(6) : 487-90, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16725265
  • Kumar, A.Soares, H.Serdarevic, F. Totality of evidence: one of the keys to better oncology management. The Journal of oncology management : the official journal of the American College of Oncology Administrators. 14(1) : 12-4, 2005. http://www.ncbi.nlm.nih.gov/pubmed/15773599
  • Kumar, A.Soares, H.Wells, R.Clarke, M.Hozo, I.Bleyer, A.Reaman, G.Chalmers, I.Djulbegovic, B. Are experimental treatments for cancer in children superior to established treatments? Observational study of randomised controlled trials by the Children's Oncology Group. BMJ (Clinical research ed.). 331(7528) : 1295, 2005. http://www.ncbi.nlm.nih.gov/pubmed/16299015
  • Soares, HP.Kumar, A.Daniels, S.Swann, S.Cantor, A.Hozo, I.Clark, M.Serdarevic, F.Gwede, C.Trotti, A.Djulbegovic, B. Evaluation of new treatments in radiation oncology: are they better than standard treatments? JAMA : the journal of the American Medical Association. 293(8) : 970-8, 2005. http://www.ncbi.nlm.nih.gov/pubmed/15728168
  • Soares, HP.Daniels, S.Kumar, A.Clarke, M.Scott, C.Swann, S.Djulbegovic, B. Bad reporting does not mean bad methods for randomised trials: observational study of randomised controlled trials performed by the Radiation Therapy Oncology Group. BMJ (Clinical research ed.). 328(7430) : 22-4, 2004. http://www.ncbi.nlm.nih.gov/pubmed/14703540
  • Kumar, A.Loughran, T.Alsina, M.Durie, BG.Djulbegovic, B. Management of multiple myeloma: a systematic review and critical appraisal of published studies. The lancet oncology. 4(5) : 293-304, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12732167
  • Djulbegovic, B.Seidenfeld, J.Bonnell, C.Kumar, A. Nonmyeloablative allogeneic stem-cell transplantation for hematologic malignancies: a systematic review. Cancer control : journal of the Moffitt Cancer Center. 10(1) : 17-41, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12598853
  • Kumar, A.Djulbegovic, B. Why evidence based oncology management. The Journal of oncology management : the official journal of the American College of Oncology Administrators. 11(6) : 13-6, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12502287