Allergy and Immunology

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Thomas Casale, MD

Professor, College Of Medicine Internal Medicine

College Of Medicine Internal Medicine

Professor, Internal Medicine, Morsani College of Medicine, University of South Florida

Contact Info Division of Allergy and Immunology
12901 Bruce B. Downs Blvd., MDC 19
Tampa, FL 33612

Academic Email: tbcasale@health.usf.edu

Academic Phone: (813) 972-7662

View My C.V.

Education

  • MD, Medicine, Rosalind Franklin University, 1977

Memberships

  • American Academy of Allergy, Asthma and Immunology (AAAAI) (Executive Vice President, 2012 - Present)
  • World Allergy Organization (WAO) (Board of Directors, 2008 - 2012)
  • American Board of Allergy and Immunology (Chair, 2005 - 2006)

Recent Publications

  • Casale, TB. Omalizumab for chronic urticaria. The journal of allergy and clinical immunology. In practice. 2(1) : 118-9, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24565785
  • Casale, TB.Stokes, JR. Immunotherapy: What lies beyond. The Journal of allergy and clinical immunology. 133(3) : 612-619, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24581428
  • Weller, K.Groffik, A.Church, MK.Hawro, T.Krause, K.Metz, M.Martus, P.Casale, TB.Staubach, P.Maurer, M. Development and validation of the Urticaria Control Test: A patient-reported outcome instrument for assessing urticaria control. The Journal of allergy and clinical immunology. , 2014. http://www.ncbi.nlm.nih.gov/pubmed/24522090
  • Passalacqua, G.Baena-Cagnani, CE.Bousquet, J.Canonica, GW.Casale, TB.Cox, L.Durham, SR.Larenas-Linnemann, D.Ledford, D.Pawankar, R.Potter, P.Rosario, N.Wallace, D.Lockey, RF. Grading local side effects of sublingual immunotherapy for respiratory allergy: speaking the same language. The Journal of allergy and clinical immunology. 132(1) : 93-8, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23683513
  • Calderon, MA.Casale, TB.Nelson, HS.Demoly, P. An evidence-based analysis of house dust mite allergen immunotherapy: a call for more rigorous clinical studies. The Journal of allergy and clinical immunology. 132(6) : 1322-36, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24139829
  • Ledford, DK.Burks, AW.Ballow, M.Cox, L.Wood, RA.Casale, TB. Statement regarding "The public health benefits of air pollution control". The Journal of allergy and clinical immunology. 130(1) : 24, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22742836
  • Ballow, M.Akdis, CA.Casale, TB.Wardlaw, AJ.Wenzel, SE.Ballas, Z.Lötvall, J. Immune response modifiers in the treatment of asthma: A PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology. The Journal of allergy and clinical immunology. 130(2) : 311-24, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22713596
  • Xie, Y.Jiang, H.Nguyen, H.Jia, S.Berro, A.Panettieri, RA.Wolff, DW.Abel, PW.Casale, TB.Tu, Y. Regulator of G protein signaling 2 is a key modulator of airway hyperresponsiveness. The Journal of allergy and clinical immunology. 130(4) : 968-76.e3, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22704538
  • Lötvall, J.Pawankar, R.Wallace, DV.Akdis, CA.Rosenwasser, LJ.Weber, RW.Wesley Burks, A.Casale, TB.Lockey, RF.Papadopoulus, N.Fineman, SM.Ledford, DK. We Call for iCAALL: International Collaboration in Asthma, Allergy and Immunology. The World Allergy Organization journal. 5(3) : 39-40, 2012. http://www.ncbi.nlm.nih.gov/pubmed/23268470
  • Calderón, MA.Cox, L.Casale, TB.Moingeon, P.Demoly, P. Multiple-allergen and single-allergen immunotherapy strategies in polysensitized patients: looking at the published evidence. The Journal of allergy and clinical immunology. 129(4) : 929-34, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22244595
  • Stokes, JR.Romero, FA.Allan, RJ.Phillips, PG.Hackman, F.Misfeldt, J.Casale, TB. The effects of an H3 receptor antagonist (PF-03654746) with fexofenadine on reducing allergic rhinitis symptoms. The Journal of allergy and clinical immunology. 129(2) : 409-12, 412.e1-2, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22196768
  • Cox, LS.Casale, TB.Nayak, AS.Bernstein, DI.Creticos, PS.Ambroisine, L.Melac, M.Zeldin, RK. Clinical efficacy of 300IR 5-grass pollen sublingual tablet in a US study: the importance of allergen-specific serum IgE. The Journal of allergy and clinical immunology. 130(6) : 1327-34.e1, 2012. http://www.ncbi.nlm.nih.gov/pubmed/23122534
  • Brozek, JL.Kraft, M.Krishnan, JA.Cloutier, MM.Lazarus, SC.Li, JT.Santesso, N.Strunk, RC.Casale, TB. Long-acting β2-agonist step-off in patients with controlled asthma. Archives of internal medicine. 172(18) : 1365-75, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22928176
  • Busse, WW.Ballas, ZK.Casale, TB.Cox, L.Dimov, V.Honsinger, RW.Jones, CA.Tracy, JM. Future of allergy/immunology task force report. The Journal of allergy and clinical immunology. 130(4) : 1009-10, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22921869
  • Jiang, H.Xie, Y.Abel, PW.Toews, ML.Townley, RG.Casale, TB.Tu, Y. Targeting phosphoinositide 3-kinase γ in airway smooth muscle cells to suppress interleukin-13-induced mouse airway hyperresponsiveness. The Journal of pharmacology and experimental therapeutics. 342(2) : 305-11, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22543031
  • Lewis, E.Fernandez, C.Nella, A.Hopp, R.Gallagher, JC.Casale, TB. Relationship of 25-hydroxyvitamin D and asthma control in children. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 108(4) : 281-2, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22469451
  • Lötvall, J.Pawankar, R.Wallace, DV.Akdis, CA.Rosenwasser, LJ.Weber, RW.Burks, AW.Casale, TB.Lockey, RF.Papadopoulos, NG.Fineman, SM.Ledford, DK. We call for iCAALL: International Collaboration for Asthma, Allergy and Immunology. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 108(4) : 215-6, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22469437
  • Lötvall, J.Pawankar, R.Wallace, DV.Akdis, CA.Rosenwasser, LJ.Weber, RW.Burks, AW.Casale, TB.Lockey, RF.Papadopoulos, NG.Fineman, SM.Ledford, DK. We call for iCAALL: International Collaboration in Asthma, Allergy and Immunology. The Journal of allergy and clinical immunology. 129(4) : 904-5, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22365583
  • Casale, TB.Korenblat, PE.Meltzer, EO.Yen, K.Bhatnagar, A. Nasal carbon dioxide for the symptomatic treatment of perennial allergic rhinitis. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 107(4) : 364-70, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21962098
  • Nguyen, TH.Casale, TB. Immune modulation for treatment of allergic disease. Immunological reviews. 242(1) : 258-71, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21682751
  • Calderón, MA.Casale, TB.Togias, A.Bousquet, J.Durham, SR.Demoly, P. Allergen-specific immunotherapy for respiratory allergies: from meta-analysis to registration and beyond. The Journal of allergy and clinical immunology. 127(1) : 30-8, 2011. http://www.ncbi.nlm.nih.gov/pubmed/20965551
  • Casale, TB.Stokes, JR. Future forms of immunotherapy. The Journal of allergy and clinical immunology. 127(1) : 8-15; quiz 16-7, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21094518
  • Lötvall, J.Akdis, CA.Bacharier, LB.Bjermer, L.Casale, TB.Custovic, A.Lemanske, RF.Wardlaw, AJ.Wenzel, SE.Greenberger, PA. Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome. The Journal of allergy and clinical immunology. 127(2) : 355-60, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21281866
  • Nguyen, TH.Stokes, JR.Casale, TB. Future forms of immunotherapy and immunomodulators in allergic disease. Immunology and allergy clinics of North America. 31(2) : 343-65, x-xi, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21530824
  • Stokes, JR.Casale, TB. Allergic rhinitis and asthma: celebrating 100 years of immunotherapy. Current opinion in immunology. 23(6) : 808-13, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21862303
  • Jia, S.Zhang, X.He, DZ.Segal, M.Berro, A.Gerson, T.Wang, Z.Casale, TB. Expression and function of a novel variant of estrogen receptor-α36 in murine airways. American journal of respiratory cell and molecular biology. 45(5) : 1084-9, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21642591
  • Morrow, LE.Kollef, MH.Casale, TB. Probiotic prophylaxis of ventilator-associated pneumonia: a blinded, randomized, controlled trial. American journal of respiratory and critical care medicine. 182(8) : 1058-64, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20522788
  • Sandhu, MS.Casale, TB. The role of vitamin D in asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 105(3) : 191-9; quiz 200-2, 217, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20800785
  • Brozek, JL.Bousquet, J.Baena-Cagnani, CE.Bonini, S.Canonica, GW.Casale, TB.van Wijk, RG.Ohta, K.Zuberbier, T.Schünemann, HJ. Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 revision. The Journal of allergy and clinical immunology. 126(3) : 466-76, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20816182
  • Bousquet, PJ.Bachert, C.Canonica, GW.Casale, TB.Mullol, J.Klossek, JM.Zuberbier, T.Bousquet, J. Uncontrolled allergic rhinitis during treatment and its impact on quality of life: a cluster randomized trial. The Journal of allergy and clinical immunology. 126(3) : 666-8.e1-5, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20816198
  • Dimov, VV.Casale, TB. Immunomodulators for asthma. Allergy, asthma & immunology research. 2(4) : 228-34, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20885907
  • Bousquet, J.Mantzouranis, E.Cruz, AA.Aït-Khaled, N.Baena-Cagnani, CE.Bleecker, ER.Brightling, CE.Burney, P.Bush, A.Busse, WW.Casale, TB.Chan-Yeung, M.Chen, R.Chowdhury, B.Chung, KF.Dahl, R.Drazen, JM.Fabbri, LM.Holgate, ST.Kauffmann, F.Haahtela, T.Khaltaev, N.Kiley, JP.Masjedi, MR.Mohammad, Y.O'Byrne, P.Partridge, MR.Rabe, KF.Togias, A.van Weel, C.Wenzel, S.Zhong, N.Zuberbier, T. Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organization Consultation on Severe Asthma. The Journal of allergy and clinical immunology. 126(5) : 926-38, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20926125
  • Jiang, H.Abel, PW.Toews, ML.Deng, C.Casale, TB.Xie, Y.Tu, Y. Phosphoinositide 3-kinase gamma regulates airway smooth muscle contraction by modulating calcium oscillations. The Journal of pharmacology and experimental therapeutics. 334(3) : 703-9, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20501633
  • Warrier, P.Casale, TB. Omalizumab in idiopathic anaphylaxis. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 102(3) : 257-8, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19354075
  • Reddel, HK.Taylor, DR.Bateman, ED.Boulet, LP.Boushey, HA.Busse, WW.Casale, TB.Chanez, P.Enright, PL.Gibson, PG.de Jongste, JC.Kerstjens, HA.Lazarus, SC.Levy, ML.O'Byrne, PM.Partridge, MR.Pavord, ID.Sears, MR.Sterk, PJ.Stoloff, SW.Sullivan, SD.Szefler, SJ.Thomas, MD.Wenzel, SE. An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. American journal of respiratory and critical care medicine. 180(1) : 59-99, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19535666
  • Bellamkonda, P.Warrier, P.Stokes, JR.Chiang, DT.Clark, JP.Romero, FA.Casale, TB. Limitations of objective measures of asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 102(6) : 530-1, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19558014
  • Bousquet, J.Bachert, C.Canonica, GW.Casale, TB.Cruz, AA.Lockey, RJ.Zuberbier, T. Unmet needs in severe chronic upper airway disease (SCUAD). The Journal of allergy and clinical immunology. 124(3) : 428-33, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19660803
  • Berger, WE.Ratner, PH.Casale, TB.Meltzer, EO.Wall, GM. Safety and efficacy of olopatadine hydrochloride nasal spray 0.6% in pediatric subjects with allergic rhinitis. Allergy and asthma proceedings : the official journal of regional and state allergy societies. 30(6) : 612-23, 2009. http://www.ncbi.nlm.nih.gov/pubmed/20031007
  • Mehta, V.Stokes, JR.Berro, A.Romero, FA.Casale, TB. Time-dependent effects of inhaled corticosteroids on lung function, bronchial hyperresponsiveness, and airway inflammation in asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 103(1) : 31-7, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19663124
  • Casale, TB.Canonica, GW.Bousquet, J.Cox, L.Lockey, R.Nelson, HS.Passalacqua, G. Recommendations for appropriate sublingual immunotherapy clinical trials. The Journal of allergy and clinical immunology. 124(4) : 665-70, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19766297
  • Rachelefsky, GS.Casale, TB.Blaiss, MS. Introduction. Clinical cornerstone. 9(3) : 6-8, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19781510
  • Casale, TB.Martin, RJ. Clinical importance of identifying immunoglobulin E-mediated disease in patients with asthma. Clinical cornerstone. 9(3) : 20-9, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19781512
  • Quan, M.Casale, TB.Blaiss, MS. Should clinicians routinely determine rhinitis subtype on initial diagnosis and evaluation? A debate among experts. Clinical cornerstone. 9(3) : 54-60, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19781517
  • Dimov, VV.Stokes, JR.Casale, TB. Immunomodulators in asthma therapy. Current allergy and asthma reports. 9(6) : 475-83, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19814921
  • Warrier, PJ.Bellamkonda, P.Stokes, JR.Casale, TB. Utility and limitations of objective measures of asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 102(6) : 518-22, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19558012
  • Casale, TB.Stokes, J. Anti-IgE therapy: clinical utility beyond asthma. The Journal of allergy and clinical immunology. 123(4) : 770-1.e1, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19348915
  • Jones, DH.Romero, FA.Casale, TB. Time-dependent inhibition of histamine-induced cutaneous responses by oral and intramuscular diphenhydramine and oral fexofenadine. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 100(5) : 452-6, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18517077
  • Casale, TB.van Wijk, RG. Guidelines for treatment of pediatric asthma. JAMA : the journal of the American Medical Association. 299(24) : 2855; author reply 2855, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18577728
  • Segal, M.Stokes, JR.Casale, TB. Anti-immunoglobulin e therapy. The World Allergy Organization journal. 1(10) : 174-83, 2008. http://www.ncbi.nlm.nih.gov/pubmed/23282676
  • Waggoner, D.Stokes, J.Casale, TB. Asthma and obesity. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 101(6) : 641-3, 2008. http://www.ncbi.nlm.nih.gov/pubmed/19119710
  • Waggoner, D.Stokes, J.Romero, F.Casale, TB. Dyspnea and obesity in African American women. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 101(6) : 644-5, 2008. http://www.ncbi.nlm.nih.gov/pubmed/19119711
  • Casale, TB.Stokes, JR. Immunomodulators for allergic respiratory disorders. The Journal of allergy and clinical immunology. 121(2) : 288-96; quiz 297-8, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18269921
  • Casale, TB.Romero, FA.Spierings, EL. Intranasal noninhaled carbon dioxide for the symptomatic treatment of seasonal allergic rhinitis. The Journal of allergy and clinical immunology. 121(1) : 105-9, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18028997
  • Klunker, S.Saggar, LR.Seyfert-Margolis, V.Asare, AL.Casale, TB.Durham, SR.Francis, JN. Combination treatment with omalizumab and rush immunotherapy for ragweed-induced allergic rhinitis: Inhibition of IgE-facilitated allergen binding. The Journal of allergy and clinical immunology. 120(3) : 688-95, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17631952
  • Sugiura, H.Liu, X.Duan, F.Kawasaki, S.Togo, S.Kamio, K.Wang, XQ.Mao, L.Ahn, Y.Ertl, RF.Bargar, TW.Berro, A.Casale, TB.Rennard, SI. Cultured lung fibroblasts from ovalbumin-challenged "asthmatic" mice differ functionally from normal. American journal of respiratory cell and molecular biology. 37(4) : 424-30, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17575074
  • Greenberger, PA.Ballow, M.Casale, TB.Platts-Mills, TA.Sampson, HA. Sublingual immunotherapy and subcutaneous immunotherapy: issues in the United States. The Journal of allergy and clinical immunology. 120(6) : 1466-8, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17936891
  • Stokes, J.Fenstad, E.Casale, TB. Managing impairment in patients with allergic rhinitis. Allergy and asthma proceedings : the official journal of regional and state allergy societies. 27(1) : 12-6, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16598987
  • Clark, J.Chiang, D.Casale, TB. Omalizumab in the treatment of allergic respiratory disease. The Journal of asthma : official journal of the Association for the Care of Asthma. 43(2) : 87-93, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16517423
  • Casale, TB.Kessler, J.Romero, FA. Safety of the intranasal toll-like receptor 4 agonist CRX-675 in allergic rhinitis. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 97(4) : 454-6, 2006. http://www.ncbi.nlm.nih.gov/pubmed/17069098
  • Parks, KW.Casale, TB. Anti-immunoglobulin E monoclonal antibody administered with immunotherapy. Allergy and asthma proceedings : the official journal of regional and state allergy societies. 27(2 Suppl 1) : S33-6, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16722330
  • Stokes, JR.Casale, TB. Allergy immunotherapy for primary care physicians. The American journal of medicine. 119(10) : 820-3, 2006. http://www.ncbi.nlm.nih.gov/pubmed/17000208
  • Nassef, M.Shapiro, G.Casale, TB. Identifying and managing rhinitis and its subtypes: allergic and nonallergic components--a consensus report and materials from the Respiratory and Allergic Disease Foundation. Current medical research and opinion. 22(12) : 2541-8, 2006. http://www.ncbi.nlm.nih.gov/pubmed/17265594
  • Casale, TB.Busse, WW.Kline, JN.Ballas, ZK.Moss, MH.Townley, RG.Mokhtarani, M.Seyfert-Margolis, V.Asare, A.Bateman, K.Deniz, Y. Omalizumab pretreatment decreases acute reactions after rush immunotherapy for ragweed-induced seasonal allergic rhinitis. The Journal of allergy and clinical immunology. 117(1) : 134-40, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16387596
  • Busse, WW.Casale, TB.Dykewicz, MS.Meltzer, EO.Bird, SR.Hustad, CM.Grant, E.Zeldin, RK.Edelman, JM. Efficacy of montelukast during the allergy season in patients with chronic asthma and seasonal aeroallergen sensitivity. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 96(1) : 60-8, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16440534
  • Brownell, J.Lin, H.Bewtra, A.Townley, R.Casale, TB. Necrotizing pneumonia with a questionable lung mass in a 59-year-old man. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 96(1) : 116-21, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16440543
  • Stokes, J.Kessler, R.Philip, G.Casale, TB. Ragweed skin test responsiveness correlates with specific immunoglobulin E levels. Allergy and asthma proceedings : the official journal of regional and state allergy societies. 26(2) : 103-7, 2005. http://www.ncbi.nlm.nih.gov/pubmed/15971467
  • Chiang, DT.Clark, J.Casale, TB. Omalizumab in asthma: approval and postapproval experience. Clinical reviews in allergy & immunology. 29(1) : 3-16, 2005. http://www.ncbi.nlm.nih.gov/pubmed/16222080
  • Lai, L.Casale, TB.Stokes, J. Pediatric allergic rhinitis: treatment. Immunology and allergy clinics of North America. 25(2) : 283-99, vi, 2005. http://www.ncbi.nlm.nih.gov/pubmed/15878456
  • Casale, TB.Dykewicz, MS. Clinical implications of the allergic rhinitis-asthma link. The American journal of the medical sciences. 327(3) : 127-38, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15090751
  • Lin, H.Boesel, KM.Griffith, DT.Prussin, C.Foster, B.Romero, FA.Townley, R.Casale, TB. Omalizumab rapidly decreases nasal allergic response and FcepsilonRI on basophils. The Journal of allergy and clinical immunology. 113(2) : 297-302, 2004. http://www.ncbi.nlm.nih.gov/pubmed/14767445
  • Casale, TB. Omalizumab: an effective anti-IgE treatment for allergic asthma and rhinitis. Drugs of today (Barcelona, Spain : 1998). 40(4) : 367-76, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15190389
  • Brownell, J.Casale, TB. Anti-IgE therapy. Immunology and allergy clinics of North America. 24(4) : 551-68, v, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15474858
  • Stokes, J.Casale, TB. Rationale for new treatments aimed at IgE immunomodulation. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 93(3) : 212-7; quiz 217-9, 271, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15478378
  • Casale, TB. Status of immunotherapy: current and future. The Journal of allergy and clinical immunology. 113(6) : 1036-9, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15208579
  • Prussin, C.Griffith, DT.Boesel, KM.Lin, H.Foster, B.Casale, TB. Omalizumab treatment downregulates dendritic cell FcepsilonRI expression. The Journal of allergy and clinical immunology. 112(6) : 1147-54, 2003. http://www.ncbi.nlm.nih.gov/pubmed/14657874
  • Meltzer, EO.Casale, TB.Gold, MS.O'Connor, R.Reitberg, D.del Rio, E.Weiler, JM.Weiler, K. Efficacy and safety of clemastine-pseudoephedrine-acetaminophen versus pseudoephedrine-acetaminophen in the treatment of seasonal allergic rhinitis in a 1-day, placebo-controlled park study. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 90(1) : 79-86, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12546342
  • Casale, TB. Small airway inflammation: a new therapeutic target in asthma. Introduction. Postgraduate medicine. 113(2 Suppl) : 5-6, 2003. http://www.ncbi.nlm.nih.gov/pubmed/19667622
  • Casale, TB. The pathophysiology of small airway inflammation in asthma. Postgraduate medicine. 113(2 Suppl) : 7-12, 2003. http://www.ncbi.nlm.nih.gov/pubmed/19667623
  • Casale, TB. Asthma: imaging of the smaller airways. Postgraduate medicine. 113(2 Suppl) : 13-4, 2003. http://www.ncbi.nlm.nih.gov/pubmed/19667624
  • Gottlieb, AB.Casale, TB.Frankel, E.Goffe, B.Lowe, N.Ochs, HD.Roberts, JL.Washenik, K.Vaishnaw, AK.Gordon, KB. CD4+ T-cell-directed antibody responses are maintained in patients with psoriasis receiving alefacept: results of a randomized study. Journal of the American Academy of Dermatology. 49(5) : 816-25, 2003. http://www.ncbi.nlm.nih.gov/pubmed/14576659
  • Casale, TB.Nelson, HS.Kemp, J.Parasuraman, B.Uryniak, T.Liljas, B. Budesonide Turbuhaler delivered once daily improves health-related quality of life and maintains improvements with a stepped-down dose in adults with mild to moderate asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 90(3) : 323-30, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12669896
  • Casale, TB. Small airway asthma therapy, challenges, and the future. Postgraduate medicine. 113(2 Suppl) : 15-20, 2003. http://www.ncbi.nlm.nih.gov/pubmed/19667625
  • Casale, TB.Blaiss, MS.Gelfand, E.Gilmore, T.Harvey, PD.Hindmarch, I.Simons, FE.Spangler, DL.Szefler, SJ.Terndrup, TE.Waldman, SA.Weiler, J.Wong, DF. First do no harm: managing antihistamine impairment in patients with allergic rhinitis. The Journal of allergy and clinical immunology. 111(5) : S835-42, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12743547
  • Lin, H.Casale, TB. Treatment of allergic asthma. The American journal of medicine. 113 Suppl 9A: 8S-16S, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12517577
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Positions Held

  • Chief, Allergy & Immunology (School of Medicine, Creighton University 2001 - 2013)
  • Professor (Internal Medicine, School of Medicine, Creighton University 2000 - 2013)

Awards/Honors

  • Harold Kaiser Lectureship (. - 2012)
  • Board of Directors Service Award (World Allergy Organization - 2011)
  • Scientific Progran Committee Award (World Allergy Organization Vice Chair - 2011)
  • Ira Finegold Lectureship (American College of Allergy Asthma &Immunology - 2011)
  • Gail G. Shapiro Memorial Lecture (2011 Northwest Allergy Forum - 2011)
  • Andrew Grant, MD, Honorary Lectureship (. - 2010)
  • R Jerry Dolovich MD, Memorial Lectureship (27th Annual Symposium Allergy Update 2010 - 2010)
  • The Monroe Coleman Memorial Lecture (New England Society of Allergy - 2009)