Michael Teng, PhD

Assistant Professor, College Of Medicine Molecular Medicine

Assistant Professor, College Of Medicine Pediatrics

Assistant Professor, Cop Dept Of Pharmaceutical Science

Assoc Professor, College Of Medicine Internal Medicine

College Of Medicine Internal Medicine

Assistant Professor, Internal Medicine, College of Medicine, USF

Associate Professor, Internal Medicine, Morsani College of Medicine, USF

Contact Info 12901 Bruce B. Downs Blvd. MDC19
MDC 19
Tampa, FL 33612

Academic Email: mteng@health.usf.edu

Academic Phone: (813) 974-5184

View My C.V.

Education

  • PhD, Immunology, University Of Chicago, 1993
  • Ph.D., Immunology, University of Chicago, 1993
  • B.S., Life Sciences, MIT, 1988

Interdisciplinary and Emerging Signature Programs

  • Allergy, Immunology & Infectious Disease
  • Biomedical Engineering & Nanomedicine

Research Interests

  • We study the role of host-virus interactions in viral pathogenesis. In particular, we are interested in how respiratory syncytial virus affects host signal transduction pathways to enhance viral replication. We use a combination of biochemical, molecular and cell biological, and virological techniques to examine these questions.

Memberships

  • American Society for Virology (Member, 2004 - Present)

Recent Publications

  • Wu, W.Tran, KC.Teng, MN.Heesom, KJ.Matthews, DA.Barr, JN.Hiscox, JA. The Interactome of the Human Respiratory Syncytial Virus NS1 Protein Highlights Multiple Effects on Host Cell Biology. Journal of virology. 86(15) : 7777-89, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22593156
  • Teng, MN. The non-structural proteins of RSV: targeting interferon antagonists for vaccine development. Infectious disorders drug targets. 12(2) : 129-37, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22335499
  • Hanley, LL.McGivern, DR.Teng, MN.Djang, R.Collins, PL.Fearns, R. Roles of the respiratory syncytial virus trailer region: effects of mutations on genome production and stress granule formation. Virology. 406(2) : 241-52, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20701943
  • Ghildyal, R.Ho, A.Dias, M.Soegiyono, L.Bardin, PG.Tran, KC.Teng, MN.Jans, DA. The respiratory syncytial virus matrix protein possesses a Crm1-mediated nuclear export mechanism. Journal of virology. 83(11) : 5353-62, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19297465
  • Ling, Z.Tran, KC.Teng, MN. Human respiratory syncytial virus nonstructural protein NS2 antagonizes the activation of beta interferon transcription by interacting with RIG-I. Journal of virology. 83(8) : 3734-42, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19193793
  • Ling, Z.Tran, KC.Arnold, JJ.Teng, MN. Purification and characterization of recombinant human respiratory syncytial virus nonstructural protein NS1. Protein expression and purification. 57(2) : 261-70, 2008. http://www.ncbi.nlm.nih.gov/pubmed/17997327
  • Sun, M.Fuentes, SM.Timani, K.Sun, D.Murphy, C.Lin, Y.August, A.Teng, MN.He, B. Akt plays a critical role in replication of nonsegmented negative-stranded RNA viruses. Journal of virology. 82(1) : 105-14, 2008. http://www.ncbi.nlm.nih.gov/pubmed/17959676
  • Tran, KC.He, B.Teng, MN. Replacement of the respiratory syncytial virus nonstructural proteins NS1 and NS2 by the V protein of parainfluenza virus 5. Virology. 368(1) : 73-82, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17632199
  • Fuentes, S.Tran, KC.Luthra, P.Teng, MN.He, B. Function of the respiratory syncytial virus small hydrophobic protein. Journal of virology. 81(15) : 8361-6, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17494063
  • Ghildyal, R.Li, D.Peroulis, I.Shields, B.Bardin, PG.Teng, MN.Collins, PL.Meanger, J.Mills, J. Interaction between the respiratory syncytial virus G glycoprotein cytoplasmic domain and the matrix protein. The Journal of general virology. 86(Pt 7) : 1879-84, 2005. http://www.ncbi.nlm.nih.gov/pubmed/15958665
  • Johnson, TR.Teng, MN.Collins, PL.Graham, BS. Respiratory syncytial virus (RSV) G glycoprotein is not necessary for vaccine-enhanced disease induced by immunization with formalin-inactivated RSV. Journal of virology. 78(11) : 6024-32, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15141000
  • Tran, KC.Collins, PL.Teng, MN. Effects of altering the transcription termination signals of respiratory syncytial virus on viral gene expression and growth in vitro and in vivo. Journal of virology. 78(2) : 692-9, 2004. http://www.ncbi.nlm.nih.gov/pubmed/14694100
  • Spann, KM.Collins, PL.Teng, MN. Genetic recombination during coinfection of two mutants of human respiratory syncytial virus. Journal of virology. 77(20) : 11201-11, 2003. http://www.ncbi.nlm.nih.gov/pubmed/14512568
  • Polack, FP.Teng, MN.Collins, PL.Prince, GA.Exner, M.Regele, H.Lirman, DD.Rabold, R.Hoffman, SJ.Karp, CL.Kleeberger, SR.Wills-Karp, M.Karron, RA. A role for immune complexes in enhanced respiratory syncytial virus disease. The Journal of experimental medicine. 196(6) : 859-65, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12235218
  • Teng, MN.Collins, PL. The central conserved cystine noose of the attachment G protein of human respiratory syncytial virus is not required for efficient viral infection in vitro or in vivo. Journal of virology. 76(12) : 6164-71, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12021350

Positions Held

  • Assistant Professor (Biochemistry and Molecular Biology, Eberly College of Science, Pennsylvania State University 2002 - 2010)