Thomas B. Casale K-4334-2013

Thomas B. Casale, MD

Professor, Internal Medicine, Morsani College of Medicine

Professor, College of Medicine Internal Medicine

Professor, College of Medicine Pediatrics

Contact Info Division of Allergy and Immunology
12901 Bruce B. Downs Blvd., MDC 19
Tampa FL 33612

Academic Email: tbcasale@health.usf.edu

Academic Phone:(813) 972-7631

View My C.V.

Education

  • MD, Medicine, Rosalind Franklin University, 1977

Interdisciplinary and Emerging Signature Programs

  • Allergy, Immunology & Infectious Disease

Memberships

  • American Academy of Allergy, Asthma and Immunology (AAAAI) (Executive Vice President, 2012 - Present)
  • World Allergy Organization (WAO) (Board of Directors, 2008 - 2012)
  • American Board of Allergy and Immunology (Chair, 2005 - 2006)

Recent Publications

  • Nelson HS, Calderon MA, Bernstein DI, Casale TB, Durham SR, Andersen JS, Esch R, Cox LS, Nolte H. Allergen Immunotherapy Clinical Trial Outcomes and Design: Working Toward Harmonization of Methods and Principles. Current allergy and asthma reports. 17(3) : 18, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28293909
  • Ricketti PA, Alandijani S, Lin CH, Casale TB. Investigational new drugs for allergic rhinitis. Expert opinion on investigational drugs. 26(3) : 279-292, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28141955
  • Demoly P, Makatsori M, Casale TB, Calderon MA. The Potential Role of Allergen Immunotherapy in Stepping Down Asthma Treatment. The journal of allergy and clinical immunology. In practice. 5(3) : 640-648, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28042004
  • Casale TB, Cox LS, Wahn U, Golden DBK, Bons B, Didier A. Safety Review of 5-Grass Pollen Tablet from Pooled Data of Clinical Trials. The journal of allergy and clinical immunology. In practice. , 2017. http://www.ncbi.nlm.nih.gov/pubmed/28734858
  • Casale TB, Onder RF, Berkowitz RB, Korenblat PE. Nasal Carbon Dioxide Used As Needed in the Symptomatic Treatment of Seasonal Allergic Rhinitis. The journal of allergy and clinical immunology. In practice. , 2017. http://www.ncbi.nlm.nih.gov/pubmed/28705451
  • Brożek JL, Bousquet J, Agache I, Agarwal A, Bachert C, Bosnic-Anticevich S, Brignardello-Petersen R, Canonica GW, Casale T, Chavannes NH, Correia de Sousa J, Cruz AA, Cuello-Garcia CA, Demoly P, Dykewicz M, Etxeandia-Ikobaltzeta I, Florez ID, Fokkens W, Fonseca J, Hellings PW, Klimek L, Kowalski S, Kuna P, Laisaar KT, Larenas-Linnemann DE, Lødrup Carlsen KC, Manning PJ, Meltzer E, Mullol J, Muraro A, O'Hehir R, Ohta K, Panzner P, Papadopoulos N, Park HS, Passalacqua G, Pawankar R, Price D, Riva JJ, Roldán Y, Ryan D, Sadeghirad B, Samolinski B, Schmid-Grendelmeier P, Sheikh A, Togias A, Valero A, Valiulis A, Valovirta E, Ventresca M, Wallace D, Waserman S, Wickman M, Wiercioch W, Yepes-Nuñez JJ, Zhang L, Zhang Y, Zidarn M, Zuberbier T, Schünemann HJ. Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines-2016 revision. The Journal of allergy and clinical immunology. , 2017. http://www.ncbi.nlm.nih.gov/pubmed/28602936
  • Casale TB. Biologics and biomarkers for asthma, urticaria, and nasal polyposis. The Journal of allergy and clinical immunology. 139(5) : 1411-1421, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28477720
  • Dixon AE, Castro M, Gerald LB, Holbrook JT, Henderson RJ, Casale TB, Irvin CG, Black K, Wise RA, Sugar EA. Effect of intranasal corticosteroids on allergic airway disease in asthma. The journal of allergy and clinical immunology. In practice. 5(4) : 1125-1128.e3, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28396113
  • Tabatabaian F, Ledford DK, Casale TB. Biologic and New Therapies in Asthma. Immunology and allergy clinics of North America. 37(2) : 329-343, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28366480
  • Tanno LK, Casale T, Papadopoulos NG, Sanchez-Borges M, Thiens F, Pawankar R, Calderon MA, Gómez M, Sisul JC, Ansotegui IJ, Sublett J, Demoly P. A call to arms of specialty societies to review the WHO International Classification of Diseases, Eleventh Revision terms appropriate for the diseases they manage: The example of the Joint Allergy Academies. Allergy and asthma proceedings. 38(4) : 54-55, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28668104
  • Pepper AN, Renz H, Casale TB, Garn H. Biologic Therapy and Novel Molecular Targets of Severe Asthma. The journal of allergy and clinical immunology. In practice. 5(4) : 909-916, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28689841
  • Tanno LK, Calderon MA, Li J, Casale T, Demoly P. Updating Allergy and/or Hypersensitivity Diagnostic Procedures in the WHO ICD-11 Revision. The Journal of Allergy and Clinical Immunology. In practice. 4(4) : 650-7, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27107691
  • Stokes JR, Casale TB. Characterization of asthma endotypes: implications for therapy. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 117(2) : 121-5, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27499539
  • Sarfaty M, Kreslake JM, Casale TB, Maibach EW. Views of AAAAI members on climate change and health. The Journal of Allergy and Clinical Immunology. In practice. 4(2) : 333-335.e26, 2016. http://www.ncbi.nlm.nih.gov/pubmed/26703816
  • Creticos PS, Bernstein DI, Casale TB, Lockey RF, Maloney J, Nolte H. Coseasonal Initiation of Allergen Immunotherapy: A Systematic Review. The Journal of Allergy andClinical immunology. In practice. , 2016. http://www.ncbi.nlm.nih.gov/pubmed/27349175
  • Bulkhi A, Tabatabaian F, Casale TB. Long-Acting Muscarinic Antagonists for Difficult-to-Treat Asthma: Emerging Evidence and Future Directions. Drugs. 76(10) : 999-1013, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27289376
  • Bousquet J, Schünemann HJ, Hellings PW, Arnavielhe S, Bachert C, Bedbrook A, Bergmann KC, Bosnic-Anticevich S, Brozek J, Calderon M, Canonica GW, Casale TB, Chavannes NH, Cox L, Chrystyn H, Cruz AA, Dahl R, De Carlo G, Demoly P, Devillier P, Dray G, Fletcher M, Fokkens WJ, Fonseca J, Gonzalez-Diaz SN, Grouse L, Keil T, Kuna P, Larenas-Linnemann D, Lodrup Carlsen KC, Meltzer EO, Mullol J, Muraro A, Naclerio RN, Palkonen S, Papadopoulos NG, Passalacqua G, Price D, Ryan D, Samolinski B, Scadding GK, Sheikh A, Valiulis A, Valovirta E, Walker S, Wickman M, Yorgancioglu A, Zuberbier T. MACVIA clinical decision algorithm in adolescents and adults with allergic rhinitis. The Journal of Allergy and Clinical Immunology. , 2016. http://www.ncbi.nlm.nih.gov/pubmed/27260321
  • Muraro A, Lemanske RF, Hellings PW, Akdis CA, Bieber T, Casale TB, Jutel M, Ong PY, Poulsen LK, Schmid-Grendelmeier P, Simon HU, Seys SF, Agache I. Precision medicine in patients with allergic diseases: Airway diseases and atopic dermatitis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology. The Journal of Allergy and Clinical Immunology. 137(5) : 1347-58, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27155030
  • Pepper AN, Calderón MA, Casale TB. Sublingual Immunotherapy for the Polyallergic Patient. J Allergy Clin Immunol Pract. (16) : 30268-8, 2016.
  • Li JT Bernstein DI Calderon MA Casale TB Cox L Passalacqua G Pfaar O Papadopoulos N. Sublingual grass and ragweed immunotherapy: Clinical considerations-a PRACTALL consensus report. J Allergy Clin Immunol.. 137(2) : 369-76, 2016.
  • Rosén K Maurer M Hsieh H Saini S Grattan C Gimenéz-Arnau A Agarwal S Doyle R Canvin J Kaplan A Casale T. Response to: 'Omalizumab for the treatment of chronic idiopathic or spontaneous urticaria: a critical appraisal'. Br J Dermol. 171(1) : 15-6, 2016.
  • Casale TB, Lemanske RF. In-Flight Medical Emergencies. The New England Journal of Medicine. 374(3) : 291-2, 2016. http://www.ncbi.nlm.nih.gov/pubmed/26789894
  • Xie Y, Jiang H, Zhang Q, Mehrotra S, Abel PW, Toews ML, Wolff DW, Rennard S, Panettieri RA, Casale TB, Tu Y. Upregulation of RGS2: a new mechanism for pirfenidone amelioration of pulmonary fibrosis. Respiratory research. 17(1) : 103, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27549302
  • Pepper AN, Calderón MA, Casale TB. Sublingual Immunotherapy for the Polyallergic Patient. The journal of allergy and clinical immunology. In practice. , 2016. http://www.ncbi.nlm.nih.gov/pubmed/27452888
  • Tanno LK, Calderon M, Sublett JL, Casale T, Demoly P. Smoothing the transition from International Classification of Diseases, Tenth Revision, Clinical Modification to International Classification of Diseases, Eleventh Revision. The journal of allergy and clinical immunology. In practice. , 2016. http://www.ncbi.nlm.nih.gov/pubmed/27546357
  • Nolte H, Casale TB, Lockey RF, Fogh BS, Kaur A, Lu S, Nelson HS. Epinephrine Use in Clinical Trials of Sublingual Immunotherapy Tablets. The journal of allergy and clinical immunology. In practice. , 2016. http://www.ncbi.nlm.nih.gov/pubmed/27838323
  • Zuberbier T, Abelson MB, Akdis CA, Bachert C, Berger U, Bindslev-Jensen C, Boelke G, Bousquet J, Canonica GW, Casale TB, Jutel M, Kowalski ML, Madonini E, Papadopoulos NG, Pfaar O, Sehlinger T, Bergmann KC. Validation of the Global Allergy and Asthma European Network (GA(2)LEN) chamber for trials in allergy: Innovation of a mobile allergen exposure chamber. The Journal of allergy and clinical immunology. , 2016. http://www.ncbi.nlm.nih.gov/pubmed/27697498
  • Tanno LK, Calderon MA, Papadopoulos NG, Sanchez-Borges M, Rosenwasser LJ, Bousquet J, Pawankar R, Sisul JC, Cepeda AM, Li J, Muraro A, Fineman S, Sublett JL, Katelaris CH, Chang YS, Moon HB, Casale T, Demoly P. Revisiting Desensitization and Allergen Immunotherapy Concepts for the International Classification of Diseases (ICD)-11. The Journal of Allergy and Clinical Immunology. In practice. , 2016. http://www.ncbi.nlm.nih.gov/pubmed/26969269
  • Haihong Jiang , Yan Xie , Peter W Abel , Dennis W Wolff , Myron L Toews , Reynold A. Panettieri, Jr. , Thomas B. Casale , and Yaping Tu. RGS2 Repression Exacerbates Airway Hyperresponsiveness and Remodeling in Asthma (meeting abstract) The FASEB Journal. 29(1) : 775.10, 2015.
  • Casale TB, Cole J, Beck E, Vogelmeier CF, Willers J, Lassen C, Hammann-Haenni A, Trokan L, Saudan P, Wechsler ME. CYT003, a TLR9 agonist, in persistent allergic asthma - a randomized placebo-controlled Phase 2b study. Allergy. 70(9) : 1160-8, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26042362
  • Tabatabaian F, Casale TB. Selection of patients for sublingual immunotherapy (SLIT) versus subcutaneous immunotherapy (SCIT). Allergy and asthma proceedings : the official journal of regional and state allergy societies. 36(2) : 100-4, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25715238
  • Kerstjens HA, Casale TB, Bleecker ER, Meltzer EO, Pizzichini E, Schmidt O, Engel M, Bour L, Verkleij CB, Moroni-Zentgraf P, Bateman ED. Tiotropium or salmeterol as add-on therapy to inhaled corticosteroids for patients with moderate symptomatic asthma: two replicate, double-blind, placebo-controlled, parallel-group, active-comparator, randomised trials. The Lancet. Respiratory medicine. 3(5) : 367-76, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25682232
  • Casale TB. COPD: The Not So Good, the Bad, and the Ugly! The Journal of Allergy and Clinical Immunology. In practice. 3(4) : 519-20, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26164575
  • Cooke A, Fergeson J, Bulkhi A, Casale TB. The Electronic Cigarette: The Good, the Bad, and the Ugly. The Journal of Allergy and Clinical Immunology. In practice. 3(4) : 498-505, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26164573
  • Casale TB, Bernstein JA, Maurer M, Saini SS, Trzaskoma B, Chen H, Grattan CE, Gimenéz-Arnau A, Kaplan AP, Rosén K. Similar Efficacy with Omalizumab in Chronic Idiopathic/Spontaneous Urticaria Despite Different Background Therapy. The Journal of Allergy and Clinical Immunology. In practice. 3(5) : 743–750.e1, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26054553
  • Calderon MA, Cox L, Casale TB, Mösges R, Pfaar O, Malling HJ, Sastre J, Khaitov M, Demoly P. The effect of a new communication template on anticipated willingness to initiate or resume allergen immunotherapy: an internet-based patient survey. Allergy, Asthma, and Clinical Immunology : Official journal of the Canadian Society of Allergy and Clinical Immunology. 11(1) : 17, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26015786
  • Demoly P, Calderon MA, Casale TB, Malling HJ, Wahn U. "The value of pre- and co-seasonal sublingual immunotherapy in pollen-induced allergic rhinoconjunctivitis". Clinical and Translational Allergy. 5: 18, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25941566
  • Cooke A, Bulkhi A, Casale TB. Role of biologics in intractable urticaria. Biologics : Targets & therapy. 9: 25-33, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25926715
  • Stokes JR, Casale TB. The use of anti-IgE therapy beyond allergic asthma. The Journal of Allergy and Clinical Immunology. In practice. 3(2) : 162-6, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25609342
  • Jiang H, Xie Y, Abel PW, Wolff DW, Toews ML, Panettieri RA, Casale TB, Tu Y. Regulator of G-Protein Signaling 2 Repression Exacerbates Airway Hyper-Responsiveness and Remodeling in Asthma. American Journal of Respiratory Cell and Molecular Biology. 53(1) : 42-9, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25368964
  • Li JT, Bernstein DI, Calderon MA, Casale TB, Cox L, Passalacqua G, Pfaar O, Papadopoulos NG. Sublingual grass and ragweed immunotherapy: Clinical considerations-a PRACTALL consensus report. The Journal of Allergy and Clinical Immunology. In practice. : doi:10.1016/j.jaci.2015.06.046, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26371843
  • Dhami S, Nurmatov U, Agache I, Lau S, Muraro A, Jutel M, Roberts G, Akdis C, Bonini M, Calderon M, Casale T, Cavkaytar O, Cox L, Demoly P, Flood B, Hamelmann E, Izuhara K, Kalayci Ö, Kleine-Tebbe J, Nieto A, Papadopoulos N, Pfaar O, Rosenwasser L, Ryan D, Schmidt-Weber C, Szefler S, Wahn U, van Wijk RG, Wilkinson J, Sheikh A. Allergen immunotherapy for allergic asthma: protocol for a systematic review. Clinical and Translational Allergy. 6: 5, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26862389
  • Tanno LK, Calderon MA, Goldberg BJ, Gayraud J, Bircher AJ, Casale T, Li J, Sanchez-Borges M, Rosenwasser LJ, Pawankar R, Papadopoulos NG, Demoly P. Constructing a classification of hypersensitivity/allergic diseases for ICD-11 by crowdsourcing the allergist community. Allergy. 70(6) : 609–615, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25736171
  • Casale TB, Stokes JR. Immunotherapy: What lies beyond. The Journal of allergy and clinical immunology. 133(3) : 612-619, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24581428
  • Casale TB. Omalizumab for chronic urticaria. The Journal of Allergy and Clinical Immunology. In practice. 2(1) : 118-9, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24565785
  • Barnes PJ Casale TB Dahl R Pavord ID Wechsler ME. The Asthma Control Questionnaire as a clinical trial endpoint: past experience and recommendations for future use. Allergy.. 69(9) : 1119-40, 2014.
  • Thomas B. Casale, A. Wesley Burks. Hymenoptera-Sting Hypersensitivity N Engl J Med. 370: 1432-1439, 2014.
  • Casale TB, Burks AW. Clinical practice. Hymenoptera-sting hypersensitivity. The New England Journal of Medicine. 370(15) : 1432-9, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24716682
  • Weller K, Groffik A, Church MK, Hawro T, Krause K, Metz M, Martus P, Casale TB, Staubach P, Maurer M. Development and validation of the Urticaria Control Test: A patient-reported outcome instrument for assessing urticaria control. The Journal of allergy and clinical immunology. 133(5) : 1365–1372.e6, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24522090
  • Calderon MA, Casale TB, Nelson HS, Demoly P. An evidence-based analysis of house dust mite allergen immunotherapy: a call for more rigorous clinical studies. The Journal of allergy and clinical immunology. 132(6) : 1322-36, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24139829
  • Cox L Aaronson D Casale TB Honsinger R Weber R. Allergy Immunotherapy Safety: Location Matters! J Allergy Clinical Immunology: In Practice. 1(5) : 455-457, 2013.
  • Kurtis S. Elward, Thomas B. Casale, Wilson Pace , Michael Schatz, Ryan Walters, Paul Turner. Comparison of Characteristics of Asthma Patients Seeking Care From Specialists Versus Primary Care Physicians Journal of Allergy and Clinical Immunology. 131(2) : AB34, 2013.
  • Thomas B. Casale, Kurt Elward, Wilson Pace, Paul Turner, Ryan Walters, Michael Schatz. Characteristics of Asthma Patients Seeking Specialist Care Journal of Allergy and Clinical Immunology. 131(2) : AB107, 2013.
  • Yan Xie, Haihong Jiang, Peter W. Abel, Thomas B. Casale, Reynold A. Panettieri and Yaping Tu. RGS2 repression increases susceptibility of mice to interleukin- 13-induced airway hyperresponsiveness FASEB Journal. 27: 1095.8, 2013.
  • Stokes J Casale TB. The biology of IgE, Up To Date, Wolters-Kluwer. : http://www.uptodate.com/contents/the-biology-of-ige, 2013.
  • Stokes J Casale TB. The relationship between IgE and allergic disease. Up To Date. : http://www.uptodate.com/contents/anti-ige-therapy, 2013.
  • Burks AW Calderon MA Casale T Cox L Demoly P Jutel M Nelson H Akdis CA. Update on Allergy Immunotherapy: American Academy of Allergy, Asthma and Immunology/European Allergy and Clinical Immunology/PRACTALL Consensus Report. J Allergy Clin Immunol. , 2013.
  • Demoly P Calderon M Casale TB Scadding G Annesi-Maesano I Braun J-J Delaisi B Haddad T Malard O Trébuchon F Serrano E. Assessments of disease control in allergic rhinitis. Clin Translational Allergy.. 3(1) : 7, 2013.
  • Maurer M Rosen K Hsieh HJ Saini S Grattan C Gimenez-Arnau A Agarwal S Doyle R Canvin J Kaplan A Casale TB. Omalizumab for the Treatment of Chronic Idiopathic/Spontaneous Urticaria. New Engl J Med.. 368(10) : 924-35, 2013.
  • Casale TB Olsen J DelasAlas HC. Aquagenic Urticaria. J Allergy Clin Immunol In Practice. 1(3) : 295-296, 2013.
  • Calderón MA Casale TB Cox L Akdis AC Burks AW Nelson H Jutel M Demoly P. Allergen immunotherapy: a new semantic frameworkfrom the European Academy of Allergy and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL consensus report. Allergy.. 68(7) : 825-8, 2013.
  • Creticos P Maloney J Bernstein DI Casale TB Kaur A Fisher R Liu N Murphy K Nékám K Nolte H. Long-term Efficacy and Tolerability Results of a Novel Ragweed Allergen Immunotherapy Tablet in North American and European Adults. J Allergy Clin Immunol. 131(5) : 1342-1349, 2013.
  • Vashisht P Casale TB. Omalizumab for Treatment of Allergic Rhinitis. Expert Opinion On Biological Therapy.. 13(6) : 933-945, 2013.
  • Burks AW Calderon MA Casale T Cox L Demoly P Jutel M Nelson H Akdis CA. Update on Allergy Immunotherapy: American Academy of Allergy, Asthma and Immunology/European Allergy and Clinical Immunology/PRACTALL Consensus Report. J Allergy Clin Immunol. 131(5) : 1288-1296, 2013.
  • Cruz C Casale TB. Anaphylaxis to cat in a child with exclusive sensitivity to Fel d 1. J Allergy Clin Immunol In Practice.. 1(4) : 416-417, 2013.
  • Passalacqua G, Baena-Cagnani CE, Bousquet J, Canonica GW, Casale TB, Cox L, Durham SR, Larenas-Linnemann D, Ledford D, Pawankar R, Potter P, Rosario N, Wallace D, Lockey RF. Grading local side effects of sublingual immunotherapy for respiratory allergy: speaking the same language. The Journal of allergy and clinical immunology. 132(1) : 93-8, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23683513
  • Lötvall J, Pawankar R, Wallace DV, Akdis CA, Rosenwasser LJ, Weber RW, Wesley Burks A, Casale TB, Lockey RF, Papadopoulus N, Fineman SM, Ledford DK. We Call for iCAALL: International Collaboration in Asthma, Allergy and Immunology. The World Allergy Organization journal. 5(3) : 39-40, 2012. http://www.ncbi.nlm.nih.gov/pubmed/23268470
  • Cox LS, Casale TB, Nayak AS, Bernstein DI, Creticos PS, Ambroisine L, Melac M, Zeldin RK. Clinical efficacy of 300IR 5-grass pollen sublingual tablet in a US study: the importance of allergen-specific serum IgE. The Journal of allergy and clinical immunology. 130(6) : 1327-34.e1, 2012. http://www.ncbi.nlm.nih.gov/pubmed/23122534
  • Brozek JL, Kraft M, Krishnan JA, Cloutier MM, Lazarus SC, Li JT, Santesso N, Strunk RC, Casale TB. Long-acting β2-agonist step-off in patients with controlled asthma. Archives of internal medicine. 172(18) : 1365-75, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22928176
  • Busse WW, Ballas ZK, Casale TB, Cox L, Dimov V, Honsinger RW, Jones CA, Tracy JM. Future of allergy/immunology task force report. The Journal of allergy and clinical immunology. 130(4) : 1009-10, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22921869
  • Ledford DK, Burks AW, Ballow M, Cox L, Wood RA, Casale TB. Statement regarding "The public health benefits of air pollution control". The Journal of allergy and clinical immunology. 130(1) : 24, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22742836
  • Ballow M, Akdis CA, Casale TB, Wardlaw AJ, Wenzel SE, Ballas Z, Lötvall J. Immune response modifiers in the treatment of asthma: A PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology. The Journal of allergy and clinical immunology. 130(2) : 311-24, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22713596
  • Xie Y, Jiang H, Nguyen H, Jia S, Berro A, Panettieri RA, Wolff DW, Abel PW, Casale TB, Tu Y. Regulator of G protein signaling 2 is a key modulator of airway hyperresponsiveness. The Journal of allergy and clinical immunology. 130(4) : 968-76.e3, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22704538
  • Jiang H, Xie Y, Abel PW, Toews ML, Townley RG, Casale TB, Tu Y. Targeting phosphoinositide 3-kinase γ in airway smooth muscle cells to suppress interleukin-13-induced mouse airway hyperresponsiveness. The Journal of pharmacology and experimental therapeutics. 342(2) : 305-11, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22543031
  • Lewis E, Fernandez C, Nella A, Hopp R, Gallagher JC, Casale TB. Relationship of 25-hydroxyvitamin D and asthma control in children. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 108(4) : 281-2, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22469451
  • Lötvall J, Pawankar R, Wallace DV, Akdis CA, Rosenwasser LJ, Weber RW, Burks AW, Casale TB, Lockey RF, Papadopoulos NG, Fineman SM, Ledford DK. We call for iCAALL: International Collaboration for Asthma, Allergy and Immunology. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 108(4) : 215-6, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22469437
  • Lötvall J, Pawankar R, Wallace DV, Akdis CA, Rosenwasser LJ, Weber RW, Burks AW, Casale TB, Lockey RF, Papadopoulos NG, Fineman SM, Ledford DK. We call for iCAALL: International Collaboration in Asthma, Allergy and Immunology. The Journal of allergy and clinical immunology. 129(4) : 904-5, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22365583
  • Calderón MA, Cox L, Casale TB, Moingeon P, Demoly P. Multiple-allergen and single-allergen immunotherapy strategies in polysensitized patients: looking at the published evidence. The Journal of allergy and clinical immunology. 129(4) : 929-34, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22244595
  • Stokes JR, Romero FA, Allan RJ, Phillips PG, Hackman F, Misfeldt J, Casale TB. The effects of an H3 receptor antagonist (PF-03654746) with fexofenadine on reducing allergic rhinitis symptoms. The Journal of allergy and clinical immunology. 129(2) : 409-12, 412.e1-2, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22196768
  • Bousquet J Heinzerling L Bachert C Papadopoulos NG Bousquet PJ Burney PG Canonica W Carlsen KH Cox L Haahtela T Lodrup Carlsen KC Price D Samolinski B Simons FE Wickman M Annesi-Maesano I Baena-Cagnani CE Bergmann KC Bindslev-Jensen C Casale TB et al. Practical guide to skin prick tests in allergy to aeroallergens. Allergy. 67(1) : 18-24, 2012.
  • WHO collaborating Center for Asthma and Rhinitis Bousquet J Anto JM Demoly P Schunemann JH Toaiga A et al. Severe chronic allergy (and related) diseases: a uniform approach– a MedALL-GA(2)LEN –ARIA position paper. Int Arch Allergy Immunol. 158(3) : 216-231, 2012.
  • Polosa R Casale T. Monoclonal antibodies for chronic refractory asthma and pipeline developments. Drug Discov Today.. , 2012.
  • Lötvall J Pawankar R Wallace DV Akdis CA Rosenwasser LJ Weber RW Wesley Burks A Casale TB Lockey RF Papadopoulos NG Fineman SM Ledford DK; on behalf of the American Academy of Allergy Asthma & Immunology (AAAAI) the American College of Allergy Asthma & Immunology (ACAAI) the European Academy of Allergy and Clinical Immunology (EAACI) and the Word Allergy Organisation (WAO). We call for iCAALL: International Collaboration in Asthma, Allergy and Immunology. Allergy.. 67(4) : 449-50, 2012.
  • Lotvall J Pawankar R Wallace DC Ajdus CA Rosenwasser LJ Weber RW Wesley Burks A Casale TB et al. American Academy of Allergy, Asthma & Immunology (AAAA&I) The American College of Allergy, Asthma & Imunoogy (ACAAI), the European Academy of Allergy and Clinical Immunology, and the World Allergy Organization (WAO): We call for iCAALL: International collaboration for asthma, allergy and immunology. Ann Allergy Asthma Immunol. 108(4) : 215-16, 2012.
  • Yorgancıoğlu A Ozdemir C Kalaycu O Kalyocu AF Bachert C Baena-Cagnani CE Casale TB Chen YZ Cruz AA Demoly P Fokkens WJ Lodrup Carlsen KC Mohammad Y Mullol J Ohta K Papadopoulos NG Pawankar R Samolinski B Schünemann HJ Yusuf OM Zuberbier T Bousquet J. [ARIA (Allergic rhinitis and its impact on asthma) Achievements in 10 years and future needs]. Tuberk Toraks. 60(1) : 92-7, 2012.
  • Papadopoulos NG Arakawa H Carlsen KH Custovic A Gern J Lemanske R Souef P Mäkelä M Roberts G Wong G Zar H Akdis CA Bacharier LB Baraldi E van Bever HP de Blic J Boner A Burks W Casale TB Castro-Rodriguez JA Chen YZ El-Gamal YM Everard ML Frischer T Geller M Gereda J Goh DY Guilbert TW Hedlin G Heymann PW Hong SJ Hossny EM Huang JL Jackson DJ de Jongste JC Khaled N Kling S Kuna P Lau S Ledford DK Lee SI Liu AH Lockey RF Lødrup-Carlsen K Lötvall J Morikawa A Nieto A Paramesh H Pawankar R Pohunek P Pongracic J Price D Robertson C Rosario N Rossenwasser LJ Sly PD Stein R Stick S Szefler S Taussig LM Valovirta E Vichyanond P Wallace D Weinberg E Wennergren G Wildhaber J Zeiger RS. International consensus on (ICON) pediatric asthma. Allergy.. 67(8) : 976-997, 2012.
  • Bousquet J Schünemann HJ Baena-Cagnani CE Bachert C Bonini S Boulet LP Bousquet PJBrozek JL Canonica GW Casale TB et al. ARIA (Allergic Rhinitis and its Impact on Asthma) -Achievements in10 years and future needs. J Allergy Clin Immunol. 130(5) : 1049-1062, 2012.
  • Lotvall J Pawankar R Wallace DV Akdis CA Rosenwasser LJ Weber RW Wesley Burks A Casale TB Lockey RF Papadopoulus N Fineman SM Ledford DK; on behalf of the American Academy of Allergy Asthma & Immunology (AAAAI) the AmericanCollege of Allergy Asthma & Immunology (ACAAI) the European Academy of Allergy and Clinical Immunology (EAACI) and the World Allergy Organization (WAO). Göteborg Sweden Tampa and Ft, Lauderdale Florida Tokyo Japan Davos Switzerland Kansas City Missouri Denver Colorado Chapel Hill North Carolina Omaha Nebraska Athens Greece and 51 Atlanta Georgia. We Call for iCAALL: International Collaboration in Asthma, Allergy and Immunology. World Allergy Organ J.. 5(3) : 39-40, 2012.
  • Bousquet J Addis A Adcock I Agache I Agusti A Alonso A Annesi-Maesano I Anto JM Bachert C Baena-Cagnani CE Bai C Baigenzhin A Barbara C Barnes PJ Bateman ED Beck L Bedbrook A Bel EH Benezet O Bennoor KS Benson M Bernabeu-Wittel M Bewick M Bindslev-Jensen C Blain H Blasi F Bonini M Bonini S Boulet LP Bourdin A Bourret R Bousquet PJ Brightling CE Briggs A Brozek J Buhl R Bush A Caimmi D Calderon M Calverley P Camargos PA Camuzat T Canonica GW Carlsen KH Casale TB et al. Integrated care pathways for airway diseases (AIRWAYS-ICPs). Eur Respir J.. 44(2) : 304-23, 2012.
  • Casale TB, Korenblat PE, Meltzer EO, Yen K, Bhatnagar A. Nasal carbon dioxide for the symptomatic treatment of perennial allergic rhinitis. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 107(4) : 364-70, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21962098
  • Brożek JL Bousquet J Baena-Cagnani CE Bonini S Canonica GW Casale TB van Wijk RG Ohta K Zuberbier T Schünemann HJ. Reply. J Allergy Clin Immunol.. , 2011.
  • Nguyen TH, Casale TB. Immune modulation for treatment of allergic disease. Immunological reviews. 242(1) : 258-71, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21682751
  • Jia S, Zhang X, He DZ, Segal M, Berro A, Gerson T, Wang Z, Casale TB. Expression and function of a novel variant of estrogen receptor-α36 in murine airways. American journal of respiratory cell and molecular biology. 45(5) : 1084-9, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21642591
  • Nguyen TH, Stokes JR, Casale TB. Future forms of immunotherapy and immunomodulators in allergic disease. Immunology and allergy clinics of North America. 31(2) : 343-65, x-xi, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21530824
  • Lötvall J, Akdis CA, Bacharier LB, Bjermer L, Casale TB, Custovic A, Lemanske RF, Wardlaw AJ, Wenzel SE, Greenberger PA. Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome. The Journal of allergy and clinical immunology. 127(2) : 355-60, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21281866
  • Casale TB, Stokes JR. Future forms of immunotherapy. The Journal of allergy and clinical immunology. 127(1) : 8-15; quiz 16-7, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21094518
  • Calderón MA, Casale TB, Togias A, Bousquet J, Durham SR, Demoly P. Allergen-specific immunotherapy for respiratory allergies: from meta-analysis to registration and beyond. The Journal of allergy and clinical immunology. 127(1) : 30-8, 2011. http://www.ncbi.nlm.nih.gov/pubmed/20965551
  • Stokes JR, Casale TB. Allergic rhinitis and asthma: celebrating 100 years of immunotherapy. Current opinion in immunology. 23(6) : 808-13, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21862303
  • Lewis E Casale T. Role of Vitamin D In Asthma. Therapy,. 8(3) : 297-306, 2011.
  • Bousquet PJ Calderón MA Demoly P Larenas D Passalacqua G Bachert C Brozek J Canonica GW Casale T Fonseca J Dahl R Durham SR Merk H Worm MWahn U Zuberbier T Schünemann HJ Bousquet J. The Consolidated Standards of Reporting Trials (CONSORT) Statement applied to allergen-specific immunotherapy with inhalant allergens: Global Allergy, Asthma European Network (GA(2)LEN) article. J Allergy Clin Immunol. 127(1) : 49-56, 2011.
  • Bousquet J, Schünemann HJ, Bousquet PJ, Bachert C, Canonica GW, Casale TB, Demoly P, Durham S, Carlsen KH, Malling HJ, Passalacqua G, Simons FE, Anto J, Baena-Cagnani CE, Bergmann KC, Bieber T, Briggs AH, Brozek J, Calderon MA, Dahl R, Devillier P, Gerth van Wijk R, Howarth P, Larenas D, Papadopoulos NG, Schmid-Grendelmeier P, Zuberbier T. How to design and evaluate randomized controlled trials in immunotherapy for allergic rhinitis: an ARIA-GA(2) LEN statement. Allergy. 66(6) : 765-74, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21496059
  • Sandhu MS, Casale TB. The role of vitamin D in asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 105(3) : 191-9; quiz 200-2, 217, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20800785
  • Morrow LE, Kollef MH, Casale TB. Probiotic prophylaxis of ventilator-associated pneumonia: a blinded, randomized, controlled trial. American journal of respiratory and critical care medicine. 182(8) : 1058-64, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20522788
  • Jiang H, Abel PW, Toews ML, Deng C, Casale TB, Xie Y, Tu Y. Phosphoinositide 3-kinase gamma regulates airway smooth muscle contraction by modulating calcium oscillations. The Journal of pharmacology and experimental therapeutics. 334(3) : 703-9, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20501633
  • Massanari M, Nelson H, Casale T, Busse W, Kianifard F, Geba GP, Zeldin RK. Effect of pretreatment with omalizumab on the tolerability of specific immunotherapy in allergic asthma. The Journal of allergy and clinical immunology. 125(2) : 383-9, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20159249
  • Bousquet J, Mantzouranis E, Cruz AA, Aït-Khaled N, Baena-Cagnani CE, Bleecker ER, Brightling CE, Burney P, Bush A, Busse WW, Casale TB, Chan-Yeung M, Chen R, Chowdhury B, Chung KF, Dahl R, Drazen JM, Fabbri LM, Holgate ST, Kauffmann F, Haahtela T, Khaltaev N, Kiley JP, Masjedi MR, Mohammad Y, O'Byrne P, Partridge MR, Rabe KF, Togias A, van Weel C, Wenzel S, Zhong N, Zuberbier T. Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organization Consultation on Severe Asthma. The Journal of allergy and clinical immunology. 126(5) : 926-38, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20926125
  • Brozek JL, Bousquet J, Baena-Cagnani CE, Bonini S, Canonica GW, Casale TB, van Wijk RG, Ohta K, Zuberbier T, Schünemann HJ. Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 revision. The Journal of allergy and clinical immunology. 126(3) : 466-76, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20816182
  • Bousquet PJ, Bachert C, Canonica GW, Casale TB, Mullol J, Klossek JM, Zuberbier T, Bousquet J. Uncontrolled allergic rhinitis during treatment and its impact on quality of life: a cluster randomized trial. The Journal of allergy and clinical immunology. 126(3) : 666-8.e1-5, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20816198
  • Dimov VV, Casale TB. Immunomodulators for asthma. Allergy, asthma & immunology research. 2(4) : 228-34, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20885907
  • Bousquet J, Kiley J, Bateman ED, Viegi G, Cruz AA, Khaltaev N, Aït Khaled N, Baena-Cagnani CE, Barreto ML, Billo N, Canonica GW, Carlsen KH, Chavannes N, Chuchalin A, Drazen J, Fabbri LM, Gerbase MW, Humbert M, Joos G, Masjedi MR, Makino S, Rabe K, To T, Zhi L. Prioritised research agenda for prevention and control of chronic respiratory diseases. The European respiratory journal. 36(5) : 995-1001, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20223919
  • Quan M, Casale TB, Blaiss MS. Should clinicians routinely determine rhinitis subtype on initial diagnosis and evaluation? A debate among experts. Clinical cornerstone. 9(3) : 54-60, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19781517
  • Dimov VV, Stokes JR, Casale TB. Immunomodulators in asthma therapy. Current allergy and asthma reports. 9(6) : 475-83, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19814921
  • Casale TB, Stokes J. Anti-IgE therapy: clinical utility beyond asthma. The Journal of allergy and clinical immunology. 123(4) : 770-1.e1, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19348915
  • Warrier P, Casale TB. Omalizumab in idiopathic anaphylaxis. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 102(3) : 257-8, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19354075
  • Reddel HK, Taylor DR, Bateman ED, Boulet LP, Boushey HA, Busse WW, Casale TB, Chanez P, Enright PL, Gibson PG, de Jongste JC, Kerstjens HA, Lazarus SC, Levy ML, O'Byrne PM, Partridge MR, Pavord ID, Sears MR, Sterk PJ, Stoloff SW, Sullivan SD, Szefler SJ, Thomas MD, Wenzel SE. An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. American journal of respiratory and critical care medicine. 180(1) : 59-99, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19535666
  • Warrier PJ, Bellamkonda P, Stokes JR, Casale TB. Utility and limitations of objective measures of asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 102(6) : 518-22, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19558012
  • Bellamkonda P, Warrier P, Stokes JR, Chiang DT, Clark JP, Romero FA, Casale TB. Limitations of objective measures of asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 102(6) : 530-1, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19558014
  • Bousquet J, Bachert C, Canonica GW, Casale TB, Cruz AA, Lockey RJ, Zuberbier T. Unmet needs in severe chronic upper airway disease (SCUAD). The Journal of allergy and clinical immunology. 124(3) : 428-33, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19660803
  • Mehta V, Stokes JR, Berro A, Romero FA, Casale TB. Time-dependent effects of inhaled corticosteroids on lung function, bronchial hyperresponsiveness, and airway inflammation in asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 103(1) : 31-7, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19663124
  • Casale TB, Canonica GW, Bousquet J, Cox L, Lockey R, Nelson HS, Passalacqua G. Recommendations for appropriate sublingual immunotherapy clinical trials. The Journal of allergy and clinical immunology. 124(4) : 665-70, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19766297
  • Rachelefsky GS, Casale TB, Blaiss MS. Introduction. Clinical cornerstone. 9(3) : 6-8, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19781510
  • Berger WE, Ratner PH, Casale TB, Meltzer EO, Wall GM. Safety and efficacy of olopatadine hydrochloride nasal spray 0.6% in pediatric subjects with allergic rhinitis. Allergy and asthma proceedings : the official journal of regional and state allergy societies. 30(6) : 612-23, 2009. http://www.ncbi.nlm.nih.gov/pubmed/20031007
  • Casale TB, Martin RJ. Clinical importance of identifying immunoglobulin E-mediated disease in patients with asthma. Clinical cornerstone. 9(3) : 20-9, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19781512
  • Casale TB, Romero FA, Spierings EL. Intranasal noninhaled carbon dioxide for the symptomatic treatment of seasonal allergic rhinitis. The Journal of allergy and clinical immunology. 121(1) : 105-9, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18028997
  • Casale TB, Stokes JR. Immunomodulators for allergic respiratory disorders. The Journal of allergy and clinical immunology. 121(2) : 288-96; quiz 297-8, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18269921
  • Jones DH, Romero FA, Casale TB. Time-dependent inhibition of histamine-induced cutaneous responses by oral and intramuscular diphenhydramine and oral fexofenadine. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 100(5) : 452-6, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18517077
  • Casale TB, van Wijk RG. Guidelines for treatment of pediatric asthma. JAMA : the journal of the American Medical Association. 299(24) : 2855; author reply 2855, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18577728
  • Segal M, Stokes JR, Casale TB. Anti-immunoglobulin e therapy. The World Allergy Organization journal. 1(10) : 174-83, 2008. http://www.ncbi.nlm.nih.gov/pubmed/23282676
  • Waggoner D, Stokes J, Romero F, Casale TB. Dyspnea and obesity in African American women. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 101(6) : 644-5, 2008. http://www.ncbi.nlm.nih.gov/pubmed/19119711
  • Waggoner D, Stokes J, Casale TB. Asthma and obesity. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 101(6) : 641-3, 2008. http://www.ncbi.nlm.nih.gov/pubmed/19119710
  • Greenberger PA, Ballow M, Casale TB, Platts-Mills TA, Sampson HA. Sublingual immunotherapy and subcutaneous immunotherapy: issues in the United States. The Journal of allergy and clinical immunology. 120(6) : 1466-8, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17936891
  • Klunker S, Saggar LR, Seyfert-Margolis V, Asare AL, Casale TB, Durham SR, Francis JN. Combination treatment with omalizumab and rush immunotherapy for ragweed-induced allergic rhinitis: Inhibition of IgE-facilitated allergen binding. The Journal of allergy and clinical immunology. 120(3) : 688-95, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17631952
  • Sugiura H, Liu X, Duan F, Kawasaki S, Togo S, Kamio K, Wang XQ, Mao L, Ahn Y, Ertl RF, Bargar TW, Berro A, Casale TB, Rennard SI. Cultured lung fibroblasts from ovalbumin-challenged "asthmatic" mice differ functionally from normal. American journal of respiratory cell and molecular biology. 37(4) : 424-30, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17575074
  • Stokes JR, Casale TB. Allergy immunotherapy for primary care physicians. The American journal of medicine. 119(10) : 820-3, 2006. http://www.ncbi.nlm.nih.gov/pubmed/17000208
  • Casale TB, Kessler J, Romero FA. Safety of the intranasal toll-like receptor 4 agonist CRX-675 in allergic rhinitis. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 97(4) : 454-6, 2006. http://www.ncbi.nlm.nih.gov/pubmed/17069098
  • Nassef M, Shapiro G, Casale TB. Identifying and managing rhinitis and its subtypes: allergic and nonallergic components--a consensus report and materials from the Respiratory and Allergic Disease Foundation. Current medical research and opinion. 22(12) : 2541-8, 2006. http://www.ncbi.nlm.nih.gov/pubmed/17265594
  • Parks KW, Casale TB. Anti-immunoglobulin E monoclonal antibody administered with immunotherapy. Allergy and asthma proceedings : the official journal of regional and state allergy societies. 27(2 Suppl 1) : S33-6, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16722330
  • Casale TB, Busse WW, Kline JN, Ballas ZK, Moss MH, Townley RG, Mokhtarani M, Seyfert-Margolis V, Asare A, Bateman K, Deniz Y. Omalizumab pretreatment decreases acute reactions after rush immunotherapy for ragweed-induced seasonal allergic rhinitis. The Journal of allergy and clinical immunology. 117(1) : 134-40, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16387596
  • Busse WW, Casale TB, Dykewicz MS, Meltzer EO, Bird SR, Hustad CM, Grant E, Zeldin RK, Edelman JM. Efficacy of montelukast during the allergy season in patients with chronic asthma and seasonal aeroallergen sensitivity. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 96(1) : 60-8, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16440534
  • Brownell J, Lin H, Bewtra A, Townley R, Casale TB. Necrotizing pneumonia with a questionable lung mass in a 59-year-old man. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 96(1) : 116-21, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16440543
  • Clark J, Chiang D, Casale TB. Omalizumab in the treatment of allergic respiratory disease. The Journal of asthma : official journal of the Association for the Care of Asthma. 43(2) : 87-93, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16517423
  • Stokes J, Fenstad E, Casale TB. Managing impairment in patients with allergic rhinitis. Allergy and asthma proceedings : the official journal of regional and state allergy societies. 27(1) : 12-6, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16598987
  • Stokes J, Kessler R, Philip G, Casale TB. Ragweed skin test responsiveness correlates with specific immunoglobulin E levels. Allergy and asthma proceedings : the official journal of regional and state allergy societies. 26(2) : 103-7, 2005. http://www.ncbi.nlm.nih.gov/pubmed/15971467
  • Chiang DT, Clark J, Casale TB. Omalizumab in asthma: approval and postapproval experience. Clinical reviews in allergy & immunology. 29(1) : 3-16, 2005. http://www.ncbi.nlm.nih.gov/pubmed/16222080
  • Lai L, Casale TB, Stokes J. Pediatric allergic rhinitis: treatment. Immunology and allergy clinics of North America. 25(2) : 283-99, vi, 2005. http://www.ncbi.nlm.nih.gov/pubmed/15878456
  • Casale TB. Omalizumab: an effective anti-IgE treatment for allergic asthma and rhinitis. Drugs of today (Barcelona, Spain : 1998). 40(4) : 367-76, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15190389
  • Casale TB, Dykewicz MS. Clinical implications of the allergic rhinitis-asthma link. The American journal of the medical sciences. 327(3) : 127-38, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15090751
  • Casale TB. Status of immunotherapy: current and future. The Journal of allergy and clinical immunology. 113(6) : 1036-9, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15208579
  • Lin H, Boesel KM, Griffith DT, Prussin C, Foster B, Romero FA, Townley R, Casale TB. Omalizumab rapidly decreases nasal allergic response and FcepsilonRI on basophils. The Journal of allergy and clinical immunology. 113(2) : 297-302, 2004. http://www.ncbi.nlm.nih.gov/pubmed/14767445
  • Stokes J, Casale TB. Rationale for new treatments aimed at IgE immunomodulation. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 93(3) : 212-7; quiz 217-9, 271, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15478378
  • Brownell J, Casale TB. Anti-IgE therapy. Immunology and allergy clinics of North America. 24(4) : 551-68, v, 2004. http://www.ncbi.nlm.nih.gov/pubmed/15474858
  • Prussin C, Griffith DT, Boesel KM, Lin H, Foster B, Casale TB. Omalizumab treatment downregulates dendritic cell FcepsilonRI expression. The Journal of allergy and clinical immunology. 112(6) : 1147-54, 2003. http://www.ncbi.nlm.nih.gov/pubmed/14657874
  • Gottlieb AB, Casale TB, Frankel E, Goffe B, Lowe N, Ochs HD, Roberts JL, Washenik K, Vaishnaw AK, Gordon KB. CD4+ T-cell-directed antibody responses are maintained in patients with psoriasis receiving alefacept: results of a randomized study. Journal of the American Academy of Dermatology. 49(5) : 816-25, 2003. http://www.ncbi.nlm.nih.gov/pubmed/14576659
  • Casale TB. The pathophysiology of small airway inflammation in asthma. Postgraduate medicine. 113(2 Suppl) : 7-12, 2003. http://www.ncbi.nlm.nih.gov/pubmed/19667623
  • Casale TB. Small airway inflammation: a new therapeutic target in asthma. Introduction. Postgraduate medicine. 113(2 Suppl) : 5-6, 2003. http://www.ncbi.nlm.nih.gov/pubmed/19667622
  • Casale TB, Blaiss MS, Gelfand E, Gilmore T, Harvey PD, Hindmarch I, Simons FE, Spangler DL, Szefler SJ, Terndrup TE, Waldman SA, Weiler J, Wong DF. First do no harm: managing antihistamine impairment in patients with allergic rhinitis. The Journal of allergy and clinical immunology. 111(5) : S835-42, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12743547
  • Casale TB, Nelson HS, Kemp J, Parasuraman B, Uryniak T, Liljas B. Budesonide Turbuhaler delivered once daily improves health-related quality of life and maintains improvements with a stepped-down dose in adults with mild to moderate asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 90(3) : 323-30, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12669896
  • Casale TB. Small airway asthma therapy, challenges, and the future. Postgraduate medicine. 113(2 Suppl) : 15-20, 2003. http://www.ncbi.nlm.nih.gov/pubmed/19667625
  • Casale TB. Asthma: imaging of the smaller airways. Postgraduate medicine. 113(2 Suppl) : 13-4, 2003. http://www.ncbi.nlm.nih.gov/pubmed/19667624
  • Meltzer EO, Casale TB, Gold MS, O'Connor R, Reitberg D, del Rio E, Weiler JM, Weiler K. Efficacy and safety of clemastine-pseudoephedrine-acetaminophen versus pseudoephedrine-acetaminophen in the treatment of seasonal allergic rhinitis in a 1-day, placebo-controlled park study. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 90(1) : 79-86, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12546342
  • Lin H, Casale TB. Treatment of allergic asthma. The American journal of medicine. 113 Suppl 9A: 8S-16S, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12517577
  • Oppenheimer JJ, Casale TB. Next generation antihistamines: therapeutic rationale, accomplishments and advances. Expert opinion on investigational drugs. 11(6) : 807-17, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12036424
  • Nelson HS, Stricker W, Casale TB, Raff H, Fourré JA, Aron DC, Newman KB. A comparison of methods for assessing hypothalamic-pituitary-adrenal (HPA) axis activity in asthma patients treated with inhaled corticosteroids. Journal of clinical pharmacology. 42(3) : 319-26, 2002. http://www.ncbi.nlm.nih.gov/pubmed/11865969

Positions Held

  • Chief, Allergy & Immunology (School of Medicine, Creighton University 2001 - 2013)
  • Professor (Internal Medicine, School of Medicine, Creighton University 2000 - 2013)

Awards/Honors

  • Harold Kaiser Lectureship (. - 2012)
  • Board of Directors Service Award (World Allergy Organization - 2011)
  • Scientific Progran Committee Award (World Allergy Organization Vice Chair - 2011)
  • Ira Finegold Lectureship (American College of Allergy Asthma &Immunology - 2011)
  • Gail G. Shapiro Memorial Lecture (2011 Northwest Allergy Forum - 2011)
  • Andrew Grant, MD, Honorary Lectureship (. - 2010)
  • R Jerry Dolovich MD, Memorial Lectureship (27th Annual Symposium Allergy Update 2010 - 2010)
  • The Monroe Coleman Memorial Lecture (New England Society of Allergy - 2009)