Lakshmi Galam

Lakshmi Galam, PHD

Assistant Professor, College of Medicine Internal Medicine

Contact Info 12901 Bruce B. Downs Blvd.
MDC 19
Tampa FL 33612

Academic Email: lgalam@health.usf.edu

Academic Phone:(813) 974-5502

Education

  • PhD, Molecular Genetics, Osmania University*, 2005

Interdisciplinary and Emerging Signature Programs

  • Allergy, Immunology & Infectious Disease

Recent Publications

  • Fukumoto J, Cox R, Fukumoto I, Cho Y, Parthasarathy PT, Galam L, Lockey RF, Kolliputi N. Deletion of ASK1 Protects against Hyperoxia-Induced Acute Lung Injury. PloS one. 11(1) : e0147652, 2016. http://www.ncbi.nlm.nih.gov/pubmed/26807721
  • Galam L, Soundararajan R, Breitzig M, Rajan A, Yeruva RR, Czachor A, Harris F, Lockey RF, Kolliputi N. SOCS-1 rescues IL-1β-mediated suppression of epithelial sodium channel in mouse lung epithelial cells via ASK-1. Oncotarget. 7(20) : 29081-91, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27058411
  • Fukumoto J, Soundararajan R, Leung J, Cox R, Mahendrasah S, Muthavarapu N, Herrin T, Czachor A, Tan LC, Hosseinian N, Patel P, Gone J, Breitzig MT, Cho Y, Cooke AJ, Galam L, Narala VR, Pathak Y, Lockey RF, Kolliputi N. The role of club cell phenoconversion and migration in idiopathic pulmonary fibrosis. Aging. 8(11) : 3091-3109, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27899769
  • Galam L, Rajan A, Failla A, Soundararajan R, Lockey RF, Kolliputi N. Deletion of P2X7 attenuates hyperoxia-induced acute lung injury via inflammasome suppression. American journal of physiology. Lung cellular and molecular physiology. 310(6) : L572-81, 2016. http://www.ncbi.nlm.nih.gov/pubmed/26747786
  • Venugopal R, Galam L, Cox R, Fukumoto J, Cho Y, Parthasarathy PT, Lockey RF, Kolliputi N. Inflammasome Inhibition Suppresses Alveolar Cell Permeability Through Retention of Neuregulin-1 (NRG-1). Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 36(5) : 2012-24, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26202361
  • Galam L, Failla A, Soundararajan R, Lockey RF, Kolliputi N. 4-Hydroxynonenal regulates mitochondrial function in human small airway epithelial cells. Oncotarget. , 2015. http://www.ncbi.nlm.nih.gov/pubmed/26484418
  • Galam L, Parthasarathy PT, Cho Y, Cho SH, Lee YC, Lockey RF, Kolliputi N. Adenovirus-mediated transfer of the SOCS-1 gene to mouse lung confers protection against hyperoxic acute lung injury. Free radical biology & medicine. 84: 196-205, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25850028
  • Rajanbabu V, Galam L, Fukumoto J, Enciso J, Tadikonda P, Lane TN, Bandyopadhyay S, Parthasarathy PT, Cho Y, Cho SH, Lee YC, Lockey RF, Kolliputi N. Genipin suppresses NLRP3 inflammasome activation through uncoupling protein-2. Cellular immunology. , 2015. http://www.ncbi.nlm.nih.gov/pubmed/26123077
  • Lagishetty V, Parthasarathy PT, Phillips O, Fukumoto J, Cho Y, Fukumoto I, Bao H, Cox R, Galam L, Lockey RF, Kolliputi N. Dysregulation of CLOCK gene expression in hyperoxia-induced lung injury. American journal of physiology. Cell physiology. 306(11) : C999-C1007, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24696144
  • Bandyopadhyay S, Lane T, Venugopal R, Parthasarathy PT, Cho Y, Galam L, Lockey R, Kolliputi N. MicroRNA-133a-1 regulates inflammasome activation through uncoupling protein-2. Biochemical and biophysical research communications. 439(3) : 407-12, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23988448
  • Desai P, Tamarapu Parthasarathy P, Galam L, Lockey R, Kolliputi N. A new role for inflammasomes: sensing the disturbances in non-alcoholic fatty liver disease. Frontiers in physiology. 4: 156, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23847540
  • Jalali S, Ramanathan GK, Parthasarathy PT, Aljubran S, Galam L, Yunus A, Garcia S, Cox RR, Lockey RF, Kolliputi N. Mir-206 regulates pulmonary artery smooth muscle cell proliferation and differentiation. PloS one. 7(10) : e46808, 2012. http://www.ncbi.nlm.nih.gov/pubmed/23071643
  • Kolliputi N, Galam L, Parthasarathy PT, Tipparaju SM, Lockey RF. NALP-3 inflammasome silencing attenuates ceramide-induced transepithelial permeability. Journal of cellular physiology. 227(9) : 3310-6, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22169929
  • Tamarapu Parthasarathy P, Galam L, Huynh B, Yunus A, Abuelenen T, Castillo A, Kollongod Ramanathan G, Cox R, Kolliputi N. MicroRNA 16 modulates epithelial sodium channel in human alveolar epithelial cells. Biochemical and biophysical research communications. 426(2) : 203-8, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22940131