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Charurut Somboonwit, MD, FACP

Associate Professor of Medicine, Division of Infectious Disease & International Medicine
Director of Communicable Diseases, Hillsborough County Health Department


Contact Information

E-Mail:
Phone: (813) 844-4187
FAX: (813) 844-7605

Education

Fellowship, Infectious Disease, University of South Florida
Residency, Internal Medicine, State University of New York at Brooklyn, Far Rockaway, NY
MD, Srinakharinwirot University, Bangkok, Thailand


  • Biographical Sketch

    Dr. Somboonwit is board certified in Internal Medicine and Infectious Diseases. After completion her fellowship in infectious diseases in 2003, she joined the Polk County Health Department. While she remained active in teaching as a clinical faculty, she was responsible for HIV care in a large rural HIV clinic in central Florida. She joined University of South Florida full time in 2006. In her current position as an Associate Professor of Medicine, she also serves as Communicable Disease Director and Clinical Research Director for the Hillsborough Health Department. (link will open in new window)

    Dr. Somboonwit is active in teaching. She currently serves as faculty of the Florida AIDS Education and Teaching Center; and she co-chairs the Scholarly Concentration in Research for Medical Students. She is a member of the Gold Humanism Society and a lifetime member of Leadership Florida. Most recently Dr. Somboonwit was elected to faculty membership of the Alpha Omega Alpha society.

  • Areas of Expertise
    • Hepatitis
    • HIV/AIDS
  • Current Research

    DAIDS - START. Strategic Timing of Antiretroviral Therapy. CPCRA START. (Principal Investigator) (2009-present)

    A Pilot, Randomized, Controlled Study to Evaluate the Safety and Efficacy of Raltegravir versus NRTIs as a Backbone in HIV-Infected Patients Switched from a Stable Boosted PI Regimen. (Merck-IISP) (Principal Investigator) (2008-present)

    HIV and Cardiovascular Risks in an Urban Setting a retrospective study for cardiovascular risk factors prevalent among HIV positive patients receiving care in an urban Health Department located in Hillsborough County, FL. (Principal Investigator) (2007-present)

    A Phase III, Randomized, Double Blinded Study to Evaluate the Safety and Efficacy of Elvitegravir/Emtricitabine/Tenofovir Disoproxil Fumarate/GS-9350 versus Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naive Adults. Gilead GS-US-236-0102 (2010-present)

    A Phase III, Randomized, Double Blinded Study to Evaluate the Safety and Efficacy of Elvitegravir/Emtricitabine/Tenofovir Disoproxil Fumarate/GS-9350 versus Ritonavir-Boosted Atazanavir plus Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naive Adults. Gilead GS-US-236-0103 (2010-present)

    A Phase III, Randomized, Double Blinded Study to Evaluate the Safety and Efficacy of GS-9350 Boosted Atazanavir versus Ritonavir-Boosted Atazanavir, Each Administered with Emtricitabine/Tenofovir Disoproxil Fumarate HIV-1 Infected, Antiretroviral Treatment-Naive Adults. Gilead GS-US-236-0124 (2010-present)

    A Phase III, Randomized, Double-Blind Study of TMC278 25 mg once daily in Combination with a Fixed Background Regimen Consisting of Tenofovir Disoproxil Fumarate and Emtricitabine in Antiretroviral-Naive HIV-1 Infected Subjects. Tibotec (TMC278-209) (2008-present)

    A Multicenter, Randomized, Double-Blind, Double-Dummy, Phase 3 Study of the Safety and Efficacy of Ritonavir-Boosted Elvitegravir (EVG/r) Versus Raltegravir (RAL) Each Administered With a Background Regimen in HIV-1 Infected, Antiretroviral Treatment-Experienced Adults. Gilead (GS-US-183-0130) (2008 - Present)

    Pilot Study for a Multisite HIV/AIDS Clinical and Resource Use Data. Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Two- Stage Study to Assess the Efficacy and Safety of Crofelemer 125mg, 250mg, and 500mg Orally Twice Daily for the Treatment of HIV-Associated Diarrhea [ADVENT TRIAL] (2006-present)

    A Phase IIb, Randomized, Partially Blinded, Dose-Finding Trial of TMC278 in Antiretroviral Naive HIV-1 Infected Subjects. Tibotec TMZ278-C204. (2005-present)

    A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of a Novel CCR5 Antagonist, UK-427,857, in Combination with Optimized Background Therapy Versus Optimized Background Therapy Along for the Treatment of Antiretroviral-Experienced HIV-1 Infected Subjects. Pfizer A4001027. (2005-present)

  • Publications

    Sinnott JT, Somboonwit C, Shapshak P. XMRV 2011, in progress, 2012

    Shapshak P, Alrabaa S, Somboonwit C, Sinnott JT. Zika Virus Review, in progress, 2012

    Alrabaa S, Castillo E, Nguyen P, Somboonwit C, Sriaroon C, Sinnott JT, Shapshak P. West Nile Virus Review, in progress, 2012

    Shapshak P, Duncan R, Kangueane P, Somboonwit C, Sinnott JT, Commins D, Singer E, Levine A. HIV Associated Dementia and HIV Encephalitis II: Genes on Chromosome 22 Expressed in Individually Microdissected Globus Pallidus Neurons (Preliminary analysis). Bioinformation 2011; 6(5): 183-186

    Shapshak P, Somboonwit C, Sinnott JT, Commins D, Singer E, Levine AJ. Gene-Chromosome Locations of Neuropsychiatric Diseases. Bioinformation 2011; 7(7): 366-368

    Mouzakis J, Somboonwit C, Lakshmi S, Rumbak M, Sinnott JT, Cherpelis B, Keshishian J. Levamisole Induced Necrosis of the Skin and Neutropenia Following Intranasal Cocaine Use: A Newly Recognized Syndrome. J Drubs Dermatol 2011 Oct 1; 10(10): 1204-7

    Shapshak P, Duncan R, Duran EM, Farinetti F, Minagar A, Commins D, Rodriguez H, Chiappelli F, Kangueane P, Levine AJ, Singer E, Somboonwit C, Sinnott JT. Gene Expression for HIV-Associated Dementia and HIV Encephalitis in Microdissected Neurons: Preliminary Analysis. Neurobehavioral HIV Medicine 2011; 3:53-78

    Shapshak P, Chiappelli F, Somboonwit C, Sinnott JT. The Influenza Pandemic of 2009: Lessons and Implications. Mol Diagn Ther 2011 Apr 1; 15(2):63-81

    Barkhordarian A, Iyer N, Shapshak P, Somboonwit C, Sinnott JT, Chiappelli F. Influenza 2009 Pandemic: Cellular Immunemediated Surveillance Modulated by TH17 & Tregs. Bioinformation 2011 Mar 2; 6(1):39-40

    Shamini G, Ravishandran M, Sinnott JT, Somboonwit C, Sidhu H, Shapshak P, Kangueane P. Structural Inferences for Cholera Toxin Mutations in Vibrio cholerae.Bioinformation 2011 Mar; 6(1):1-9

    Sinnott JT, Somboonwit C, Oxner A. Clostridium tetani in a Haitian Refugee. Clin Microbiol Newsl 2011 Mar; 33(5):37-39

    Sowmya G, Shamini G, Anita S, Sakharkar M, Mathura V, Rodriguez H, Levine A, Singer E, Commins D, Somboonwit C, Sinnott JT, Sidhu H, et al. HIV-1 Envelope Accessible Surface and Polarity: Clade, Blood and Brain. Bioinformation 2011 March; 6(2):48-56

    Wu A, Shah M, Somboonwit C. Pre-exposure Prophylaxis for the Prevention of HIV Infection in Med Who Have Sex with Men Interim Guidance. Carelink. Vol 12, Issue 5, Apr 25, 2011. Available online.

    Somboonwit C, Smith KM. Prevention and Treatment of Opportunistic Infections (OIs) in HIV-Infected Adult and Adolescents Guidelines Summary. CareLink. Vol 12, Issue 4. Mar 22, 2011. Available online.

    Pham T. Alrabaa ST, Hung L, Somboonwit C, Montero JA. The HIV Virologic Outcomes of Different Interventions among HAART Experienced Patients with Two Consecutive Detectable Low-level Viremia. JIAPAC 2011 Jan-Feb; 10(1):54-6

    Soliman EZ, Lundgren JD, Roediger MP, Duprez DA, Temesgen Z, Bickel M, Shlay J, Somboonwit C, Reiss P, Stein JH, Neaton JR, on behalf of the SMART/INSIGHT student group. Association between Ritonavir Boosted Protease Inhibitors with QTc and PR Interval Durations in the Strategies for Management of Antiretroviral Therapy (SMART) Trial. AIDS 2011 Jan 28; 25(3):367-77

    Shapshak P, Pandjassarame K, Fujimura RK, Commins D, Chiappelli F, Singer E, Levine A, Minagar A, Novembre F, Somboonwit C, Nath A, Sinnott JT. NeuroAIDS Review. Editorial. AIDS 2011; 25:123-141

    Somboonwit C, Kurtyka D, Velez AP. Abacanvir and lamivudine combination. Expert Opin Drig Metabl Toxicol 2009 Dec 5(12):1599-606

    Shapshak P, Somboonwit C, Drumright LN, Frost S DW, et al. Molecular and Contextual Markers of HCV and Drug Abuse. Mol Diag and Ther, in press, 2009

  • Book Chapters

    Somboonwit C, Menezes LJ. Kaposi’s Sarcoma (KS). In J Beal, J Orrick, K Alfonso, M Rathore (eds.), HIV/AIDS Primary Care Guide. Norfolk, CT. Crown House Publishing Company LLC, 2006. Pp. 369-375

    Somboonwit C. Infections in Lung Cancer Patients. In Greene JN (ed.), Infections in Cancer Patients. New York: Marcel Dekker, 2004. Pp. 187-197

    Somboonwit C, Poklepovic A, Irvine L, Sinnott JT. Infectious disease aspects of viral hemorrhagic fever. In: Soule BM ed. The American Practitioner in Infection Control. St. Louis: Mosby-Year Book, Inc., 2004

    Somboonwit C. Infections in Lung Cancer Patients. In Greene JN (ed.), Infections in Cancer Patients. New York: Marcel Dekker, 2004. Pp. 187-197

    Somboonwit C. Infections in Head and Neck Cancer Patients. In Greene JN (ed.), Infections in Cancer Patients. New York: Marcel Dekker, 2004. Pp. 177-185

    Somboonwit C. Viral Hemorrhagic Fever. In APIC Text of Infection Control & Epidemiology. Washington, DC: Association for Professionals in Infection Control and Epidemiology, 2005. Pp. 90(1-11)

  • Abstracts

    Pham T, Montero J, Somboonwit C. Comparison of Virologic Outcome in Different Treatment Approaches for HIV Patients with Persistent Low-Level Viremia. Bristol-Myers-Squibb Virology Fellows Program. Philadelphia, PA, 2009

    Menezes L, D’Souza KR, D’Souza KM, Somboonwit C, Amin S, Sinnott J. A socio-historical construction of the AIDS epidemic in India. Abstract: MOPE0724. Presentation at the XVI International AIDS Conference. Toronto, 2006

    Nadler JP, Wills TS, Somboonwit C, et al. Anemia prevalence among HIV patients: antiretroviral therapy and other risk factors: abstract 1151. 2nd IAS Conference on HIV Pathogenesis and Treatment, Paris, 2003

    Somboonwit C, Greene JN, Haight DO. Pulmonary Penicilliosis Marneffei in a Cancer Patient without Endemic Area Exposure: A Case Report. Focus on Fungal Infections. Phoenix, 2002

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    Dr. Somboonwit's CV