Naoki Tajiri, P.T., Ph.D.




Contact Info 12901 Bruce B. Downs Blvd., MDC77
Tampa, FL 33612

Academic Email:

Academic Phone: (813) 974-1666

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  • PhD, Biophysiological Science, Okayama University, 2010
  • MSc, Cytology and Histology, Okayama University, 2006
  • BS, Physical Therapy, Kibi International University, 2004

Interdisciplinary and Emerging Signature Programs

  • Allergy, Immunology & Infectious Disease
  • Biomedical Engineering & Nanomedicine
  • Cellular and Molecular Biology
  • Neurodegenerative Disease
  • Neuroscience

Research Interests

  • Dr. Naoki Tajiri champions translational biomedical research in advancing combined stem cell and rehabilitation therapy for neurological disorders. He pioneered the novel brain repair mechanism of stem cell-paved biobridges as a key substrate in guiding the host cells to reach their destination even across non-neurogenic and injured tissues. His background is in regenerative medicine with specialized training in stem cell biology and rehabilitation therapy.


  • The Japan Society of Molecular Neurosurgery (General, 2008 - Present)
  • The Japan Neuroscience Society (JNS) (General, 2007 - Present)
  • Japanese Physical Therapy Association (JPTA) (General, 2007 - Present)
  • Society for Neuroscience (SFN) (General, 2006 - Present)

Recent Publications

  • Kaneko, Y.Shojo, H.Burns, J.Staples, M.Tajiri, N.Borlongan, CV. DJ-1 ameliorates ischemic cell death in vitro possibly via mitochondrial pathway. Neurobiology of disease. 62: 56-61, 2014.
  • Tajiri, N.Acosta, SA.Shahaduzzaman, M.Ishikawa, H.Shinozuka, K.Pabon, M.Hernandez-Ontiveros, D.Kim, DW.Metcalf, C.Staples, M.Dailey, T.Vasconcellos, J.Franyuti, G.Gould, L.Patel, N.Cooper, D.Kaneko, Y.Borlongan, CV.Bickford, PC. Intravenous transplants of human adipose-derived stem cell protect the brain from traumatic brain injury-induced neurodegeneration and motor and cognitive impairments: cell graft biodistribution and soluble factors in young and aged rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34(1) : 313-26, 2014.
  • Ishikawa, H.Tajiri, N.Shinozuka, K.Vasconcellos, J.Kaneko, Y.Lee, HJ.Mimura, O.Dezawa, M.Kim, SU.Borlongan, CV. Vasculogenesis in experimental stroke after human cerebral endothelial cell transplantation. Stroke; a journal of cerebral circulation. 44(12) : 3473-81, 2013.
  • Franzblau, M.Gonzales-Portillo, C.Gonzales-Portillo, GS.Diamandis, T.Borlongan, MC.Tajiri, N.Borlongan, CV. Vascular damage: a persisting pathology common to Alzheimer's disease and traumatic brain injury. Medical hypotheses. 81(5) : 842-5, 2013.
  • Tajiri, N.Kellogg, SL.Shimizu, T.Arendash, GW.Borlongan, CV. Traumatic brain injury precipitates cognitive impairment and extracellular aβ aggregation in Alzheimer's disease transgenic mice. PloS one. 8(11) : e78851, 2013.
  • Kaneko, Y.Tajiri, N.Shojo, H.Borlongan, CV. Oxygen-Glucose-Deprived Rat Primary Neural Cells Exhibit DJ-1 Translocation into Healthy Mitochondria: A Potent Stroke Therapeutic Target. CNS neuroscience & therapeutics. , 2013.
  • Tajiri, N.Kaneko, Y.Shinozuka, K.Ishikawa, H.Yankee, E.McGrogan, M.Case, C.Borlongan, CV. Stem cell recruitment of newly formed host cells via a successful seduction? Filling the gap between neurogenic niche and injured brain site. PloS one. 8(9) : e74857, 2013.
  • Tajiri, N.Dailey, T.Metcalf, C.Mosley, YI.Lau, T.Staples, M.van Loveren, H.Kim, SU.Yamashima, T.Yasuhara, T.Date, I.Kaneko, Y.Borlongan, CV. In vivo animal stroke models: a rationale for rodent and non-human primate models. Translational stroke research. 4(3) : 308-21, 2013.
  • Ishikawa, H.Tajiri, N.Vasconcellos, J.Kaneko, Y.Mimura, O.Dezawa, M.Borlongan, CV. Ischemic stroke brain sends indirect cell death signals to the heart. Stroke; a journal of cerebral circulation. 44(11) : 3175-82, 2013.
  • Tajiri, N.Acosta, S.Glover, LE.Bickford, PC.Jacotte Simancas, A.Yasuhara, T.Date, I.Solomita, MA.Antonucci, I.Stuppia, L.Kaneko, Y.Borlongan, CV. Intravenous grafts of amniotic fluid-derived stem cells induce endogenous cell proliferation and attenuate behavioral deficits in ischemic stroke rats. PloS one. 7(8) : e43779, 2012.
  • Tajiri, N.Lau, T.Glover, LE.Shinozuka, K.Kaneko, Y.van Loveren, H.Borlongan, CV. Cerebral aneurysm as an exacerbating factor in stroke pathology and a therapeutic target for neuroprotection. Current pharmaceutical design. 18(25) : 3663-9, 2012.
  • Kaneko, Y.Hayashi, T.Yu, S.Tajiri, N.Bae, EC.Solomita, MA.Chheda, SH.Weinbren, NL.Parolini, O.Borlongan, CV. Human amniotic epithelial cells express melatonin receptor MT1, but not melatonin receptor MT2: a new perspective to neuroprotection. Journal of pineal research. 50(3) : 272-80, 2011.
  • Borlongan, CV.Glover, LE.Tajiri, N.Kaneko, Y.Freeman, TB. The great migration of bone marrow-derived stem cells toward the ischemic brain: therapeutic implications for stroke and other neurological disorders. Progress in neurobiology. 95(2) : 213-28, 2011.
  • Tajiri, N.Yasuhara, T.Shingo, T.Kondo, A.Yuan, W.Kadota, T.Wang, F.Baba, T.Tayra, JT.Morimoto, T.Jing, M.Kikuchi, Y.Kuramoto, S.Agari, T.Miyoshi, Y.Fujino, H.Obata, F.Takeda, I.Furuta, T.Date, I. Exercise exerts neuroprotective effects on Parkinson's disease model of rats. Brain research. 1310: 200-7, 2010.