NaokiTajiriK-1230-2012

Naoki Tajiri, P.T., Ph.D.

Assistant Professor, CENTER OF EXCELLENCE FOR AGING & BRAIN REPAIR

Assistant Professor, PHYSICAL THERAPY & REHABILITATION SCIENCES

PHYSICAL THERAPY & REHABILITATION SCIENCES

Contact Info 12901 Bruce B. Downs Blvd., MDC77
Tampa, FL 33612

Academic Email: ntajiri@health.usf.edu

Academic Phone: (813) 974-1666

View My C.V.

Education

  • PhD, Biophysiological Science, Okayama University, 2010
  • MSc, Cytology and Histology, Okayama University, 2006
  • BS, Physical Therapy, Kibi International University, 2004

Interdisciplinary and Emerging Signature Programs

  • Allergy, Immunology & Infectious Disease
  • Biomedical Engineering & Nanomedicine
  • Cellular and Molecular Biology
  • Neurodegenerative Disease
  • Neuroscience

Research Interests

  • Dr. Naoki Tajiri champions translational biomedical research in advancing combined stem cell and rehabilitation therapy for neurological disorders. He pioneered the novel brain repair mechanism of stem cell-paved biobridges as a key substrate in guiding the host cells to reach their destination even across non-neurogenic and injured tissues. His background is in regenerative medicine with specialized training in stem cell biology and rehabilitation therapy.

Memberships

  • The Japan Society of Molecular Neurosurgery (General, 2008 - Present)
  • The Japan Neuroscience Society (JNS) (General, 2007 - Present)
  • Japanese Physical Therapy Association (JPTA) (General, 2007 - Present)
  • Society for Neuroscience (SFN) (General, 2006 - Present)

Recent Publications

  • Kaneko Y, Shojo H, Burns J, Staples M, Tajiri N, Borlongan CV. DJ-1 ameliorates ischemic cell death in vitro possibly via mitochondrial pathway. Neurobiology of disease. 62: 56-61, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24060818
  • Tajiri N, Acosta SA, Shahaduzzaman M, Ishikawa H, Shinozuka K, Pabon M, Hernandez-Ontiveros D, Kim DW, Metcalf C, Staples M, Dailey T, Vasconcellos J, Franyuti G, Gould L, Patel N, Cooper D, Kaneko Y, Borlongan CV, Bickford PC. Intravenous transplants of human adipose-derived stem cell protect the brain from traumatic brain injury-induced neurodegeneration and motor and cognitive impairments: cell graft biodistribution and soluble factors in young and aged rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34(1) : 313-26, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24381292
  • Ishikawa H, Tajiri N, Shinozuka K, Vasconcellos J, Kaneko Y, Lee HJ, Mimura O, Dezawa M, Kim SU, Borlongan CV. Vasculogenesis in experimental stroke after human cerebral endothelial cell transplantation. Stroke; a journal of cerebral circulation. 44(12) : 3473-81, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24130140
  • Franzblau M, Gonzales-Portillo C, Gonzales-Portillo GS, Diamandis T, Borlongan MC, Tajiri N, Borlongan CV. Vascular damage: a persisting pathology common to Alzheimer's disease and traumatic brain injury. Medical hypotheses. 81(5) : 842-5, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24074832
  • Tajiri N, Kellogg SL, Shimizu T, Arendash GW, Borlongan CV. Traumatic brain injury precipitates cognitive impairment and extracellular aβ aggregation in Alzheimer's disease transgenic mice. PloS one. 8(11) : e78851, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24223856
  • Kaneko Y, Tajiri N, Shojo H, Borlongan CV. Oxygen-Glucose-Deprived Rat Primary Neural Cells Exhibit DJ-1 Translocation into Healthy Mitochondria: A Potent Stroke Therapeutic Target. CNS neuroscience & therapeutics. , 2013. http://www.ncbi.nlm.nih.gov/pubmed/24382215
  • Tajiri N, Kaneko Y, Shinozuka K, Ishikawa H, Yankee E, McGrogan M, Case C, Borlongan CV. Stem cell recruitment of newly formed host cells via a successful seduction? Filling the gap between neurogenic niche and injured brain site. PloS one. 8(9) : e74857, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24023965
  • Tajiri N, Dailey T, Metcalf C, Mosley YI, Lau T, Staples M, van Loveren H, Kim SU, Yamashima T, Yasuhara T, Date I, Kaneko Y, Borlongan CV. In vivo animal stroke models: a rationale for rodent and non-human primate models. Translational stroke research. 4(3) : 308-21, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23682299
  • Ishikawa H, Tajiri N, Vasconcellos J, Kaneko Y, Mimura O, Dezawa M, Borlongan CV. Ischemic stroke brain sends indirect cell death signals to the heart. Stroke; a journal of cerebral circulation. 44(11) : 3175-82, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24008571
  • Tajiri N, Acosta S, Glover LE, Bickford PC, Jacotte Simancas A, Yasuhara T, Date I, Solomita MA, Antonucci I, Stuppia L, Kaneko Y, Borlongan CV. Intravenous grafts of amniotic fluid-derived stem cells induce endogenous cell proliferation and attenuate behavioral deficits in ischemic stroke rats. PloS one. 7(8) : e43779, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22912905
  • Tajiri N, Lau T, Glover LE, Shinozuka K, Kaneko Y, van Loveren H, Borlongan CV. Cerebral aneurysm as an exacerbating factor in stroke pathology and a therapeutic target for neuroprotection. Current pharmaceutical design. 18(25) : 3663-9, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22574980
  • Kaneko Y, Hayashi T, Yu S, Tajiri N, Bae EC, Solomita MA, Chheda SH, Weinbren NL, Parolini O, Borlongan CV. Human amniotic epithelial cells express melatonin receptor MT1, but not melatonin receptor MT2: a new perspective to neuroprotection. Journal of pineal research. 50(3) : 272-80, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21269327
  • Borlongan CV, Glover LE, Tajiri N, Kaneko Y, Freeman TB. The great migration of bone marrow-derived stem cells toward the ischemic brain: therapeutic implications for stroke and other neurological disorders. Progress in neurobiology. 95(2) : 213-28, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21903148
  • Tajiri N, Yasuhara T, Shingo T, Kondo A, Yuan W, Kadota T, Wang F, Baba T, Tayra JT, Morimoto T, Jing M, Kikuchi Y, Kuramoto S, Agari T, Miyoshi Y, Fujino H, Obata F, Takeda I, Furuta T, Date I. Exercise exerts neuroprotective effects on Parkinson's disease model of rats. Brain research. 1310: 200-7, 2010. http://www.ncbi.nlm.nih.gov/pubmed/19900418