Doctors of USF Health

Education

• Fellowship, Pediatric Surgery, John Hopkins University Hospital, 2004
• Fellowship, Surgical Oncology, National Cancer Institiute, 2002
• Fellowship, ECMO (Extra-Corporeal Membrane Oxygenation), Babies and Children's Hospital of New York, 1998
• Residency, General Surgery, Columbia Presbyterian Medical Center of New York, 2000
• Internship, General Surgery, Columbia Presbyterian Medical Center of New York, 1995
• MD, Columbia Univ. Col. of Phy. AND Surg., 1994

Clinical Interests

• Newborn surgery;
• Intestinal disorders;
• Conditions of the neck, chest, abdomen and pelvis in children;
• Childhood cancers;
• Melanoma, sarcoma, Wilms' tumor and neuroblastoma;
• Sentinel lymph node biopsy in children.

Research Interests

Professional Societies

• Association for Academic Surgery (Member, 2011 - Present)
• American Pediatric Surgical Association (Member, 2011 - Present)
• Association of Program Directors in Surgery (Member, 2011 - Present)
• International Society of Paediatric Surgical Oncology (Member, 2010 - Present)
• American College of Surgeons (Fellow, 2007 - Present)
• Society of Surgical Oncology (Fellow, 2006 - Present)
• American Academy of Pediatrics (Fellow, 2005 - Present)

Selected Publications

Kayton, ML.He, M.Zakowski, MF.Moreira, AL.Lau, C.Chou, AJ.Merchant, M.Merola, PR.Wexler, LH.La Quaglia, MP.Travis, WD.Ladanyi, M.
Primary lung adenocarcinomas in children and adolescents treated for pediatric malignancies.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 5(11) : 1764-71, 2010.
http://www.ncbi.nlm.nih.gov/pubmed/20975376

Kayton, ML.Garmey, EG.Ishill, NM.Cheung, NK.Kushner, BH.Kramer, K.Modak, S.Rossetto, C.Hennelly, C.Doyle, MP.Rosenberg, S.Santoro, O.La Quaglia, MP.
Preliminary results of a phase I trial of prophylactic ethanol-lock administration to prevent mediport catheter-related bloodstream infections.
Journal of pediatric surgery. 45(10) : 1961-6, 2010.
http://www.ncbi.nlm.nih.gov/pubmed/20920713

Sidebotham, EL.Sepkowitz, K.Price, AP.Steinherz, PG.La Quaglia, MP.Kayton, ML.
Eradication of cryptosporidium from a defunctionalized colon limb by refeeding stoma effluent.
Journal of pediatric surgery. 45(1) : E33-6, 2010.
http://www.ncbi.nlm.nih.gov/pubmed/20105571

Sidebotham, EL.DeLair, D.Comerci, JT.Kayton, ML.Abu-Rustum, NR.
Pediatric radical abdominal trachelectomy for solitary fibrous tumor of the uterine cervix.
Gynecologic oncology. 115(2) : 302-5, 2009.
http://www.ncbi.nlm.nih.gov/pubmed/19674775

Busam, KJ.Murali, R.Pulitzer, M.McCarthy, SW.Thompson, JF.Shaw, HM.Brady, MS.Coit, DG.Dusza, S.Wilmott, J.Kayton, M.Laquaglia, M.Scolyer, RA.
Atypical spitzoid melanocytic tumors with positive sentinel lymph nodes in children and teenagers, and comparison with histologically unambiguous and lethal melanomas.
The American journal of surgical pathology. 33(9) : 1386-95, 2009.
http://www.ncbi.nlm.nih.gov/pubmed/19609204

Magnan, H.Kayton, ML.DiMichele, DM.Araten, DJ.Kernan, NA.Boulad, F.
Splenic infarction and subsequent splenic rupture in a patient with paroxysmal nocturnal hemoglobinuria and heparin-induced thrombocytopenia.
Pediatric blood AND cancer. 53(3) : 472-4, 2009.
http://www.ncbi.nlm.nih.gov/pubmed/19415735

Kayton, ML.Wexler, LH.Lewin, SN.Park, KJ.La Quaglia, MP.Abu-Rustum, NR.
Pediatric radical abdominal trachelectomy for anaplastic embryonal rhabdomyosarcoma of the uterine cervix: an alternative to radical hysterectomy.
Journal of pediatric surgery. 44(4) : 862-7, 2009.
http://www.ncbi.nlm.nih.gov/pubmed/19361657

Kayton, ML.La Quaglia, MP.
Sentinel node biopsy for melanocytic tumors in children.
Seminars in diagnostic pathology. 25(2) : 95-9, 2008.
http://www.ncbi.nlm.nih.gov/pubmed/18697712

Kayton, ML.Delgado, R.Busam, K.Cody, HS.Athanasian, EA.Coit, D.La Quaglia, MP.
Experience with 31 sentinel lymph node biopsies for sarcomas and carcinomas in pediatric patients.
Cancer. 112(9) : 2052-9, 2008.
http://www.ncbi.nlm.nih.gov/pubmed/18338809

Paran, TS.Corbally, MT.Gross-Rom, E.Rutigliano, DN.Kayton, ML.La Quaglia, MP.
Experience with aortic grafting during excision of large abdominal neuroblastomas in children.
Journal of pediatric surgery. 43(2) : 335-40, 2008.
http://www.ncbi.nlm.nih.gov/pubmed/18280285

Kayton, ML.
Cancer and pediatric inflammatory bowel disease.
Seminars in pediatric surgery. 16(3) : 205-13, 2007.
http://www.ncbi.nlm.nih.gov/pubmed/17602977

Rutigliano, DN.Kayton, ML.Steinherz, P.Wolden, S.La Quaglia, MP.
The use of preoperative chemotherapy in Wilms' tumor with contained retroperitoneal rupture.
Journal of pediatric surgery. 42(9) : 1595-9, 2007.
http://www.ncbi.nlm.nih.gov/pubmed/17848255

Rutigliano, DN.Meyers, P.Ghossein, RA.Carlson, DL.Kayton, ML.Kraus, D.La Quaglia, MP.
Mucoepidermoid carcinoma as a secondary malignancy in pediatric sarcoma.
Journal of pediatric surgery. 42(7) : E9-13, 2007.
http://www.ncbi.nlm.nih.gov/pubmed/17618873

Rutigliano, DN.Georges, A.Wolden, SL.Kayton, ML.Meyers, P.La Quaglia, MP.
Ureteral reconstruction for retroperitoneal tumors in children.
Journal of pediatric surgery. 42(2) : 355-8, 2007.
http://www.ncbi.nlm.nih.gov/pubmed/17270548

Kayton, ML.
Pulmonary metastasectomy in pediatric patients.
Thoracic surgery clinics. 16(2) : 167-83, vi, 2006.
http://www.ncbi.nlm.nih.gov/pubmed/16805206

Kayton, ML.Huvos, AG.Casher, J.Abramson, SJ.Rosen, NS.Wexler, LH.Meyers, P.LaQuaglia, MP.
Computed tomographic scan of the chest underestimates the number of metastatic lesions in osteosarcoma.
Journal of pediatric surgery. 41(1) : 200-6; discussion 200-6, 2006.
http://www.ncbi.nlm.nih.gov/pubmed/16410133

Kayton, ML.Meyers, P.Wexler, LH.Gerald, WL.LaQuaglia, MP.
Clinical presentation, treatment, and outcome of alveolar soft part sarcoma in children, adolescents, and young adults.
Journal of pediatric surgery. 41(1) : 187-93, 2006.
http://www.ncbi.nlm.nih.gov/pubmed/16410131

Minn, AH.Kayton, M.Lorang, D.Hoffmann, SC.Harlan, DM.Libutti, SK.Shalev, A.
Insulinomas and expression of an insulin splice variant.
Lancet. 363(9406) : 363-7, 2004.
http://www.ncbi.nlm.nih.gov/pubmed/15070567

Miller, WJ.Kayton, ML.Patton, A.O'Connor, S.He, M.Vu, H.Baibakov, G.Lorang, D.Knezevic, V.Kohn, E.Alexander, HR.Stirling, D.Payvandi, F.Muller, GW.Libutti, SK.
A novel technique for quantifying changes in vascular density, endothelial cell proliferation and protein expression in response to modulators of angiogenesis using the chick chorioallantoic membrane (CAM) assay.
Journal of translational medicine. 2(1) : 4, 2004.
http://www.ncbi.nlm.nih.gov/pubmed/14754458

Kayton, ML.Costouros, NG.Lorang, D.Alexander, HR.Hewitt, SM.Cochran, C.Shalev, A.Harlan, D.Skarulis, MC.Gorden, P.Libutti, SK.
Peak stimulated insulin secretion is associated with specific changes in gene expression profiles in sporadic insulinomas.
Surgery. 134(6) : 982-7; discussion 987-8, 2003.
http://www.ncbi.nlm.nih.gov/pubmed/14668731

Kayton, ML.Libutti, SK.
Endothelial monocyte activating polypeptide II (EMAP II) enhances the effect of TNF on tumor-associated vasculature.
Current opinion in investigational drugs (London, England : 2000). 2(1) : 136-8, 2001.
http://www.ncbi.nlm.nih.gov/pubmed/11527006

Rowe, DH.Huang, J.Kayton, ML.Thompson, R.Troxel, A.O'Toole, KM.Yamashiro, D.Stolar, CJ.Kandel, JJ.
Anti-VEGF antibody suppresses primary tumor growth and metastasis in an experimental model of Wilms' tumor.
Journal of pediatric surgery. 35(1) : 30-2; discussion 32-3, 2000.
http://www.ncbi.nlm.nih.gov/pubmed/10646769

Rowe, DH.Kayton, ML.O'Toole, KM.Ingram, M.Stolar, CJ.Kandel, JJ.
Pathological angiogenesis in a murine model of human Wilms' tumor.
Journal of pediatric surgery. 34(5) : 676-9, 1999.
http://www.ncbi.nlm.nih.gov/pubmed/10359162

Kayton, ML.Rowe, DH.O'Toole, KM.Thompson, RB.Schwarz, MA.Stolar, CJ.Kandel, JJ.
Metastasis correlates with production of vascular endothelial growth factor in a murine model of human Wilms' tumor.
Journal of pediatric surgery. 34(5) : 743-7; discussion 747-8, 1999.
http://www.ncbi.nlm.nih.gov/pubmed/10359175

Marvin, MR.Kayton, ML.O'Toole, KM.Rowe, DH.DeRosa, C.Kindred, A.Trokhan, S.Chabot, J.Kandel, JJ.
A metastasizing model of anaplastic human Wilms tumor in the nude mouse.
European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift für Kinderchirurgie. 8(5) : 295-8, 1998.
http://www.ncbi.nlm.nih.gov/pubmed/9825240

Allendorf, JD.Bessler, M.Huang, J.Kayton, ML.Laird, D.Nowygrod, R.Treat, MR.
Helium-neon laser irradiation at fluences of 1, 2, and 4 J/cm2 failed to accelerate wound healing as assessed by both wound contracture rate and tensile strength.
Lasers in surgery and medicine. 20(3) : 340-5, 1997.
http://www.ncbi.nlm.nih.gov/pubmed/9138263

Kirsch, AJ.Chang, DT.Kayton, ML.Libutti, SK.Connor, JP.Hensle, TW.
Effects of diode laser welding with dye-enhanced glue on tensile strength of sutures commonly used in urology.
Lasers in surgery and medicine. 18(2) : 167-70, 1996.
http://www.ncbi.nlm.nih.gov/pubmed/8833285

Kirsch, AJ.Chang, DT.Kayton, ML.Libutti, SK.Treat, MR.Hensle, TW.
Laser welding with albumin-based solder: experimental full-tubed skin graft urethroplasty.
Lasers in surgery and medicine. 18(3) : 225-30, 1996.
http://www.ncbi.nlm.nih.gov/pubmed/8778516

Marvin, MR.Libutti, SK.Kayton, M.Kao, J.Hayward, J.Grikscheit, T.Fan, Y.Brett, J.Weinberg, A.Nowygrod, R.LoGerfo, P.Feind, C.Hansen, KS.Schwartz, M.Stern, D.Chabot, J.
A novel tumor-derived mediator that sensitizes cytokine-resistant tumors to tumor necrosis factor.
The Journal of surgical research. 63(1) : 248-55, 1996.
http://www.ncbi.nlm.nih.gov/pubmed/8661206

Kirsch, AJ.Chang, DT.Kayton, ML.Newhouse, J.Libutti, SK.Treat, MR.Connor, JP.Hensle, TW.
Sutureless rabbit bladder mucosa patch graft urethroplasty using diode laser and solder.
The Journal of urology. 153(4) : 1303-7, 1995.
http://www.ncbi.nlm.nih.gov/pubmed/7869532

Allendorf, JD.Bessler, M.Kayton, ML.Oesterling, SD.Treat, MR.Nowygrod, R.Whelan, RL.
Increased tumor establishment and growth after laparotomy vs laparoscopy in a murine model.
Archives of surgery (Chicago, Ill. : 1960). 130(6) : 649-53, 1995.
http://www.ncbi.nlm.nih.gov/pubmed/7763175

Allendorf, JD.Bessler, M.Kayton, ML.Whelan, RL.Treat, MR.Nowygrod, R.
Tumor growth after laparotomy or laparoscopy. A preliminary study.
Surgical endoscopy. 9(1) : 49-52, 1995.
http://www.ncbi.nlm.nih.gov/pubmed/7725214

Kao, J.Fan, YG.Haehnel, I.Brett, J.Greenberg, S.Clauss, M.Kayton, M.Houck, K.Kisiel, W.Seljelid, R.
A peptide derived from the amino terminus of endothelial-monocyte-activating polypeptide II modulates mononuclear and polymorphonuclear leukocyte functions, defines an apparently novel cellular interaction site, and induces an acute inflammatory response.
The Journal of biological chemistry. 269(13) : 9774-82, 1994.
http://www.ncbi.nlm.nih.gov/pubmed/7545917

Kao, J.Houck, K.Fan, Y.Haehnel, I.Libutti, SK.Kayton, ML.Grikscheit, T.Chabot, J.Nowygrod, R.Greenberg, S.
Characterization of a novel tumor-derived cytokine. Endothelial-monocyte activating polypeptide II.
The Journal of biological chemistry. 269(40) : 25106-19, 1994.
http://www.ncbi.nlm.nih.gov/pubmed/7929199

Kirsch, AJ.Hensle, TW.Chang, DT.Kayton, ML.Olsson, CA.Sawczuk, IS.
Renal effects of CO2 insufflation: oliguria and acute renal dysfunction in a rat pneumoperitoneum model.
Urology. 43(4) : 453-9, 1994.
http://www.ncbi.nlm.nih.gov/pubmed/8154067